OR5M10 Olfactory Receptor
| Gene Symbol | OR5M101 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | M |
| Pseudogene | No |
| CORP pseudogene probability score | 0.13 (functional) |
| Aliases | OR11-207, HsOR11.11.77, ORL3295 |
| External Ids | HGNC: 15290 GeneBank: BK004515, NM_001004741 ORDB: ORL3295 |
| Build #39 labels | OR5M10 |
| Chromosomal location | 11:56,576,777-56,577,721 (-) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5M1 | 95.56% | 315 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5M10C | 86% | 315 |
| Mouse | Or5m10 | 85% | 304 |
| Mouse | Or5m10b | 82% | 312 |
| Rat | Or5m10b | 83% | 312 |
| Rat | Or5m10 | 85% | 304 |
| Cow | OR5M10C | 85% | 306 |
| Orang | OR5G1 | 52% | 312 |
| Horse | OR5M10E | 86% | 315 |
| Chimp | OR5M1 | 95% | 315 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC140733 |
Sequence information
| Nucleotide sequence |
ATGTTGTCCCCAAACCACACCATAGTGACAGAATTCATTCTCTTAGGACTGACAGACGAC CCAGTGCTAGAGAAGATCCTGTTTGGGGTGTTCCTGGCGATCTACCTAATCACACTGGCA GGCAACCTGTGCATGATCCTGCTGATCAGGACCAATTCCCAACTGCAAACACCCATGTAT TTCTTCCTTGGTCACCTCTCCTTTGTAGACATTTGCTATTCTTCCAATGTTACTCCAAAT ATGCTGCACAATTTCCTCTCAGAACAGAAGACCATCTCCTACGCTGGATGCTTCACACAG TGTCTTCTCTTCATCGCCCTAGTGATCACTGAGTTTTACTTCCTTGCTTCAATGGCATTG GATCGCTATGTAGCCATTTGCAGCCCTTTACATTACAGTTCCAGGATGTCCAAGAACATT TGCATCTCTCTGGTCACTGTGCCTTACATGTATGGCTTCCTTAATGGGCTCTCTCAGACA CTGCTGACCTTTCACTTATCCTTCTGTGGCTCCCTTGAAATCAATCATTTCTACTGCGCT GATCCTCCTCTTATCATGCTGGCCTGCTCTGACACCCGTGTCAAAAAGATGGCAATGTTT GTAGTTGCAGGCTTTACTCTCTCAAGCTCTCTCTTCATCATTCTTCTGTCCTATCTTTTC ATTTTTGCAGCGATCTTCAGGATCCGTTCTGCTGAAGGCAGGCACAAAGCCTTTTCTACG TGTGCTTCCCACCTGACAATAGTCACTTTGTTTTATGGAACCCTCTTCTGCATGTACGTA AGGCCTCCATCAGAGAAGTCTGTAGAGGAGTCCAAAATAATTGCAGTCTTTTATACTTTT TTGAGCCCAATGCTGAACCCATTGATCTATAGCCTACGGAACAGAGATGTAATCCTTGCC ATACAACAAATGATTAGGGGAAAATCCTTTTGTAAAATTGCAGTT |
| Conceptual translation |
MLSPNHTIVTEFILLGLTDDPVLEKILFGVFLAIYLITLAGNLCMILLIRTNSQLQTPMY FFLGHLSFVDICYSSNVTPNMLHNFLSEQKTISYAGCFTQCLLFIALVITEFYFLASMAL DRYVAICSPLHYSSRMSKNICISLVTVPYMYGFLNGLSQTLLTFHLSFCGSLEINHFYCA DPPLIMLACSDTRVKKMAMFVVAGFTLSSSLFIILLSYLFIFAAIFRIRSAEGRHKAFST CASHLTIVTLFYGTLFCMYVRPPSEKSVEESKIIAVFYTFLSPMLNPLIYSLRNRDVILA IQQMIRGKSFCKIAV Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 56,344,993 | 56,344,993 | NS | A/C | L/V | rs10792043 (DbSNP) |
| 11 | 56,344,260 | 56,344,260 | NS | A/G | I/T | rs10896488 (DbSNP) |
| 11 | 56,344,377 | 56,344,377 | NS | A/G | I/T | rs2852415 (DbSNP) |
| 11 | 56,344,314 | 56,344,314 | NS | C/G | R/T | rs2852414 (DbSNP) |
| 11 | 56,344,915 | 56,344,915 | NS | C/T | A/T | rs59116342 (DbSNP) |
| 11 | 56,344,295 | 56,344,295 | NS | C/T | M/I | rs2852413 (DbSNP) |
| 11 | 56,344,581 | 56,344,581 | NS | G/T | T/N | rs2852416 (DbSNP) |
| 11 | 56,576,784 | 56,576,784 | NS | A/G | I/T | 1000GP (CEU, CHBJPT) |
| 11 | 100 | -100 | NS | A/G | I/T | 1000GP (YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 56,315,297 | 56,347,636 | CopyNumber | Variation_48849 (DGV) |
| 11 | 56,323,407 | 56,347,636 | CopyNumber | Variation_48850 (DGV) |
| 11 | 56,324,576 | 56,347,636 | CopyNumber | Variation_48851 (DGV) |
| CopyNumber | 134 (Hasin) | |||
| 11 | 56,342,253 | 56,345,297 | Deletion | #222 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| I313T | L162Q | T110S | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | I | L | T | 81.95 | 0.228 |
| 2 | T | L | T | 15.13 | 0.228 |
| 3 | I | L | S | 2.84 | 0.228 |
| 4 | I | Q | T | 0.08 | 0.228 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5M10.aApr07-unspliced | main_exon | 3UTR | chr11 | 56,576,774 | 56,576,777 | - |
| CDS | chr11 | 56,576,777 | 56,577,721 | - | ||