OR10A2 Olfactory Receptor
| Gene Symbol | OR10A21 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.03 (functional) |
| Aliases | OR11-86, OST363, HsOR11.4.5 |
| External Ids | HGNC: 8161 GeneBank: AF399490, BK004293, NM_001004460 |
| Build #39 labels | OR10A2P |
| Chromosomal location | 11:6,869,755-6,870,663 (+) |
| Cluster | 11@7 |
| Synteny | CLIC#24 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10A5 | 95.71% | 303 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10A5F | 94% | 303 |
| Dog | OR10A5 | 94% | 302 |
| Dog | OR10A5D | 93% | 303 |
| Dog | OR10A5E | 93% | 303 |
| Mouse | Or10a5 | 92% | 302 |
| Mouse | Or10a2 | 90% | 302 |
| Rat | Or10a5 | 91% | 302 |
| Rat | Or10a5b | 91% | 302 |
| Rat | Or10a2 | 88% | 302 |
| Cow | OR10A5 | 92% | 303 |
| Cow | OR10A5I | 91% | 302 |
| Cow | OR10A5G | 90% | 301 |
| Cow | OR10A5H | 91% | 299 |
| Orang | OR10A5J | 98% | 303 |
| Orang | OR10A5 | 95% | 303 |
| Horse | OR10A5 | 94% | 303 |
| Horse | OR10A5K | 93% | 303 |
| Chimp | OR10A5GP | 98% | 303 |
| Chimp | OR10A5 | 96% | 303 |
Sequence information
| Nucleotide sequence |
ATGAGCTTCTCTTCCCTGCCTACTGAAATACAGTCATTACTCTTTCTGACATTTCTAACC ATCTACCTGGTCACCCTGATGGGAAACTGCCTCATCATTCTGGTTACCCTAGCTGACCCC ATGCTACACAGCCCCATGTACTTCTTCCTCAGAAACTTATCTTTCCTGGAGATTGGCTTC AACCTAGTCATTGTGCCCAAAATGCTGGGGACCCTGCTTGCCCAGGACACAACCATCTCC TTCCTTGGCTGTGCCACTCAGATGTATTTCTTCTTCTTCTTTGGAGTGGCTGAATGCTTC CTCCTGGCTACCATGGCATATGACCGCTATGTGGCCATCTGCAGTCCCTTGCACTACCCA GTCATCATGAACCAAAGGACTCGTGCCAAACTGGCTGCTGCCTCCTGGTTCCCAGGCTTT CCTGTAGCTACTGTGCAGACCACATGGCTCTTCAGTTTTCCATTCTGTGGCACCAACAAG GTGAACCACTTCTTCTGTGACAGCCCACCTGTGCTGAGGCTGGTCTGTGCAGACACAGCA CTCTTTGAGATCTACGCCATCGTCGGAACCATTCTGGTGGTCATGATCCCCTGCTTGCTG ATCTTGTGTTCCTATACTCACATTGCTGCTGCCATCCTCAAGATCCCATCAGCTAAAGGG AAGAATAAAGCCTTTTCTACATGTTCCTCACACCTCCTTGTTGTCTCTCTTTTCTATATA TCATTAAGCCTCACCTACTTCCGGCCTAAATCAAATAATTCACCTGAGGGCAAGAAGCTG CTATCATTGTCCTACACTGTTATGACTCCCATGTTGAACCCCATTATCTACAGCCTGAGA AATAACGAGGTGAAGAATGCCCTCAGCAGGACGGTCTCTAAGGCCCTAGCCCTCAGAAAC TGTATCCCA |
| Conceptual translation |
MSFSSLPTEIQSLLFLTFLTIYLVTLMGNCLIILVTLADPMLHSPMYFFLRNLSFLEIGF NLVIVPKMLGTLLAQDTTISFLGCATQMYFFFFFGVAECFLLATMAYDRYVAICSPLHYP VIMNQRTRAKLAAASWFPGFPVATVQTTWLFSFPFCGTNKVNHFFCDSPPVLRLVCADTA LFEIYAIVGTILVVMIPCLLILCSYTHIAAAILKIPSAKGKNKAFSTCSSHLLVVSLFYI SLSLTYFRPKSNNSPEGKKLLSLSYTVMTPMLNPIIYSLRNNEVKNALSRTVSKALALRN CIP Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 6,891,758 | 6,891,758 | NS | A/C | K/T | rs7926083 (DbSNP) |
| 11 | 6,891,113 | 6,891,113 | NS | A/G | H/R | rs3930075 (DbSNP) |
| 11 | 6,891,605 | 6,891,605 | NS | A/G | H/R | rs10839631 (DbSNP) |
| 11 | 6,891,704 | 6,891,704 | NS | C/T | T/I | rs10839632 (DbSNP) |
| 11 | 6,891,385 | 6,891,385 | NS | G/A | A/T | rs2741764 (DbSNP) |
| 11 | 6,891,419 | 6,891,419 | NS | G/T | G/V | rs11603197 (DbSNP) |
| 11 | 6,891,528 | 6,891,528 | SYN | C/G | L/L | rs7117739 (DbSNP) |
| 11 | 6,891,540 | 6,891,540 | SYN | C/T | Y/Y | rs7117744 (DbSNP) |
| 11 | 6,891,618 | 6,891,618 | SYN | C/T | A/A | rs61737577 (DbSNP) |
| 11 | 6,870,297 | 6,870,297 | SYN | C/G | L/L | 1000GP (CEU, CHBJPT) |
| 11 | 6,870,374 | 6,870,374 | NS | A/G | H/R | 1000GP (CEU, CHBJPT) |
| 11 | 6,870,154 | 6,870,154 | NS | G/A | A/T | 1000GP (CEU, CHBJPT) |
| 11 | 6,870,473 | 6,870,473 | NS | T/C | I/T | 1000GP (CEU, CHBJPT) |
| 11 | 6,870,527 | 6,870,527 | NS | A/C | K/T | 1000GP (CEU, CHBJPT) |
| 11 | 100 | -100 | NS | G/A | A/T | 1000GP (YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | C/G | L/L | 1000GP (YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10A2.aApr07-unspliced | main_exon | CDS | chr11 | 6,869,755 | 6,870,663 | + |
| 3UTR | chr11 | 6,870,663 | 6,870,666 | + | ||