OR10A5 Olfactory Receptor
| Gene Symbol | OR10A51 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.03 (functional) |
| Aliases | OR11-403, OR11-85, HsOR11.4.4, ORL484 |
| External Ids | HGNC: 15131 GeneBank: AF324499, AF399623, BK004296, NM_178168 ORDB: ORL484 |
| Build #39 labels | OR10A5, OR10A1 |
| Chromosomal location | 11:6,845,683-6,846,633 (+) |
| Cluster | 11@7 |
| Synteny | CLIC#24 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10A2 | 95.71% | 303 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10A5F | 93% | 317 |
| Dog | OR10A5D | 92% | 317 |
| Dog | OR10A5E | 91% | 317 |
| Mouse | Or10a5 | 92% | 316 |
| Rat | Or10a5 | 91% | 316 |
| Rat | Or10a5b | 91% | 316 |
| Rat | Or10a2 | 88% | 316 |
| Cow | OR10A5I | 91% | 316 |
| Cow | OR10A5G | 90% | 315 |
| Cow | OR10A5H | 91% | 313 |
| Orang | OR10A5J | 95% | 317 |
| Horse | OR10A5K | 93% | 317 |
| Chimp | OR10A5GP | 94% | 317 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AF324499 |
| GNF Atlas2 | gnf1h07002_at |
Sequence information
| Nucleotide sequence |
ATGGCTATAGGAAACTGGACAGAAATAAGTGAATTTATCCTCATGAGCTTCTCTTCCCTA CCTACTGAAATACAGTCATTGCTCTTCCTGACATTTCTAACTATCTATTTGGTTACTCTG AAGGGAAACAGCCTCATCATTCTGGTTACCCTAGCTGACCCCATGCTACACAGCCCCATG TACTTCTTCCTCAGAAACTTATCTTTCCTGGAGATTGGCTTCAACCTAGTCATTGTGCCC AAAATGCTGGGGACCCTGCTTGCCCAGGACACAACCATCTCCTTCCTTGGCTGTGCCACT CAGATGTATTTCTTCTTCTTCTTTGGGGTAGCTGAATGCTTCCTCCTGGCTACCATGGCA TATGACCGCTATGTGGCCATCTGCAGTCCCTTGCACTACCCAGTCATCATGAACCAAAGG ACACGGGCCAAACTGGCTGCTGCTTCCTGGTTCCCAGGCTTTCCTGTAGCTACTGTGCAG ACCACATGGCTCTTCAGTTTTCCATTCTGTGGCACCAACAAGGTGAACCACTTCTTCTGT GACAGCCCGCCTGTGCTGAAGCTGGTCTGTGCAGACACAGCACTGTTTGAGATCTACGCC ATCGTCGGAACCATTCTGGTGGTCATGATCCCCTGCTTGCTGATCTTGTGTTCCTATACT CGCATTGCTGCTGCTATCCTCAAGATCCCATCAGCTAAAGGGAAGCATAAAGCCTTCTCT ACGTGCTCCTCACACCTCCTTGTTGTCTCTCTTTTCTATATATCTTCTAGCCTCACCTAC TTCTGGCCTAAATCAAATAATTCTCCTGAGAGCAAGAAGTTGTTATCATTATCCTACACT GTTGTGACTCCCATGTTGAACCCCATTATCTACAGCTTGAGAAATAGCGAGGTGAAGAAT GCCCTCAGCAGGACCTTCCACAAGGTCCTAGCCCTCAGAAACTGTATCCCA |
| Conceptual translation |
MAIGNWTEISEFILMSFSSLPTEIQSLLFLTFLTIYLVTLKGNSLIILVTLADPMLHSPM YFFLRNLSFLEIGFNLVIVPKMLGTLLAQDTTISFLGCATQMYFFFFFGVAECFLLATMA YDRYVAICSPLHYPVIMNQRTRAKLAAASWFPGFPVATVQTTWLFSFPFCGTNKVNHFFC DSPPVLKLVCADTALFEIYAIVGTILVVMIPCLLILCSYTRIAAAILKIPSAKGKHKAFS TCSSHLLVVSLFYISSSLTYFWPKSNNSPESKKLLSLSYTVVTPMLNPIIYSLRNSEVKN ALSRTFHKVLALRNCIP Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 6,867,035 | 6,867,035 | NS | A/T | K/M | rs7949377 (DbSNP) |
| 11 | 6,867,199 | 6,867,199 | NS | C/T | L/F | rs7934823 (DbSNP) |
| 11 | 6,867,635 | 6,867,635 | NS | C/T | T/M | rs60000441 (DbSNP) |
| 11 | 6,867,510 | 6,867,510 | SYN | C/T | Y/Y | rs56403411 (DbSNP) |
| 11 | 6,867,015 | 6,867,015 | SYN | C/T | T/T | rs7952340 (DbSNP) |
| 11 | 100 | -100 | SYN | T/C | T/T | 1000GP (YRI) |
| 11 | 100 | -100 | NS | A/T | K/M | 1000GP (YRI, YRI, YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| F29S | K41M | L96F | R142W | P230L | A232G | T241M | Y253C | W262R | V282M | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | F | K | L | R | P | A | T | Y | W | V | 93.39 | 0.116 |
| 2 | F | K | L | R | P | A | M | Y | W | V | 1.54 | 0.327 |
| 3 | F | K | F | R | P | A | T | Y | W | V | 1.46 | 0.116 |
| 4 | F | K | L | R | L | A | T | Y | W | V | 1.46 | 0.116 |
| 5 | F | M | L | R | P | A | T | Y | W | V | 0.77 | 0.116 |
| 6 | F | K | L | R | P | A | T | C | W | V | 0.61 | 0.034 |
| 7 | S | M | L | R | P | A | T | Y | W | V | 0.38 | 0.116 |
| 8 | F | M | L | W | P | G | T | Y | R | M | 0.38 | 0.116 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10A5.aApr07-unspliced | main_exon | 5UTR | chr11 | 6,845,652 | 6,845,683 | + |
| CDS | chr11 | 6,845,683 | 6,846,633 | + | ||
| 3UTR | chr11 | 6,846,633 | 6,846,705 | + | ||