OR10R2 Olfactory Receptor
| Gene Symbol | OR10R21 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | R |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | OR1-8, HsOR1.4.5, ORL3012 |
| External Ids | HGNC: 14820 GeneBank: AB065640, AF399582, BK004191, NM_001004472 ORDB: ORL3012 |
| Build #39 labels | OR10R2 |
| Chromosomal location | 1:158,479,911-158,480,882 (+) |
| Cluster | 1@159a |
| Synteny | CLIC#4 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10R3P | 76.38% | 309 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10R3B | 77% | 309 |
| Mouse | Or10k2 | 56% | 310 |
| Rat | Or10j7 | 55% | 305 |
| Cow | OR10R3 | 76% | 311 |
| Orang | OR10R2B | 96% | 308 |
| Horse | OR10R2C | 87% | 308 |
| Chimp | OR10R3P | 76% | 309 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | DB344720 |
| mRNA | AB529285 |
| GNF Atlas2 | gnf1h08734_at |
Sequence information
| Nucleotide sequence |
ATGTTTTACTTCTTTCCCCCTTTGCAGATCTTGGCAGAAAACCTCACCATGGTCACCGAA TTCCTGTTGCTGGGTTTTTCCAGCCTTGGTGAAATTCAGCTGGCCCTCTTTGTAGTTTTT CTTTTTCTGTATCTAGTCATTCTTAGTGGCAATGTCACCATTATCAGTGTCATCCACCTG GATAAAAGCCTCCACACACCAATGTACTTCTTCCTTGGCATTCTCTCAACATCTGAGACC TTCTACACCTTTGTCATTCTACCCAAGATGCTCATCAATCTACTTTCTGTGGCCAGGACA ATCTCCTTCAACTGTTGTGCTCTTCAAATGTTCTTCTTCCTTGGTTTTGCCATTACCAAC TGCCTGCTATTGGGTGTGATGGGTTATGATCGCTATGCTGCCATTTGTCACCCTCTGCAT TACCCCACTCTTATGAGCTGGCAGGTGTGTGGAAAACTGGCAGCTGCCTGTGCAATTGGT GGCTTCTTGGCCTCTCTTACAGTAGTAAATTTAGTTTTCAGCCTCCCTTTTTGTAGCGCC AACAAAGTCAATCATTACTTCTGTGACATCTCAGCAGTCATTCTTCTGGCTTGTACCAAC ACAGATGTTAACGAATTTGTGATATTCATTTGTGGAGTTCTTGTACTTGTGGTTCCCTTT CTGTTTATCTGTGTTTCTTATCTCTGCATTCTGAGGACTATCCTGAAGATTCCCTCAGCT GAGGGCAGACGGAAAGCGTTTTCCACCTGCGCCTCTCACCTCAGTGTTGTTATTGTTCAT TATGGCTGTGCTTCCTTCATCTACCTGAGGCCTACAGCAAACTATGTGTCCAACAAAGAC AGGCTGGTGACGGTGACATACACGATTGTCACTCCATTACTAAACCCCATGGTTTATAGC CTCAGAAACAAGGATGTCCAACTTGCTATCAGAAAAGTGTTGGGCAAGAAAGGTTCTCTA AAACTATATAAT |
| Conceptual translation |
MFYFFPPLQILAENLTMVTEFLLLGFSSLGEIQLALFVVFLFLYLVILSGNVTIISVIHL DKSLHTPMYFFLGILSTSETFYTFVILPKMLINLLSVARTISFNCCALQMFFFLGFAITN CLLLGVMGYDRYAAICHPLHYPTLMSWQVCGKLAAACAIGGFLASLTVVNLVFSLPFCSA NKVNHYFCDISAVILLACTNTDVNEFVIFICGVLVLVVPFLFICVSYLCILRTILKIPSA EGRRKAFSTCASHLSVVIVHYGCASFIYLRPTANYVSNKDRLVTVTYTIVTPLLNPMVYS LRNKDVQLAIRKVLGKKGSLKLYN Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | A/G | M/V | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 1 | 158,449,749 | 158,449,749 | NS | A/G | M/V | rs61739693 (DbSNP) |
| 1 | 158,449,758 | 158,449,758 | NS | A/G | K/E | rs62621279 (DbSNP) |
| 1 | 158,449,835 | 158,449,835 | SYN | A/C | L/L | rs62642483 (DbSNP) |
| 1 | 158,449,854 | 158,449,854 | NS | A/G | I/V | rs62642484 (DbSNP) |
| 1 | 158,450,145 | 158,450,145 | NS | A/G | M/V | rs61741730 (DbSNP) |
| 1 | 158,450,192 | 158,450,192 | SYN | C/T | A/A | rs61741711 (DbSNP) |
| 1 | 158,450,238 | 158,450,238 | NS | A/G | T/A | rs3820678 (DbSNP) |
| 1 | 158,450,314 | 158,450,314 | NS | A/G | E/G | rs6679056 (DbSNP) |
| 1 | 158,450,382 | 158,450,382 | NS | C/T | L/F | rs1418843 (DbSNP) |
| 1 | 158,450,412 | 158,450,412 | NS | C/T | P/S | rs6666585 (DbSNP) |
| 1 | 158,450,451 | 158,450,451 | NS | A/G | T/A | rs62642485 (DbSNP) |
| 1 | 158,450,529 | 158,450,529 | NS | A/T | T/S | rs62621280 (DbSNP) |
| 1 | 158,450,563 | 158,450,563 | NS | C/T | T/M | rs62642486 (DbSNP) |
| 1 | 158,480,352 | 158,480,352 | nonsense SNP | C/T | Q/* | 1000GP (CHBJPT) |
| 1 | 158,480,402 | 158,480,402 | SYN | C/T | A/A | 1000GP (CEU) |
| 1 | 158,480,448 | 158,480,448 | NS | G/A | A/T | 1000GP (CEU, CHBJPT) |
| 1 | 158,480,524 | 158,480,524 | NS | A/G | E/G | 1000GP (CEU, CHBJPT) |
| 1 | 158,480,592 | 158,480,592 | NS | C/T | L/F | 1000GP (CEU, CHBJPT) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| M17V | E20K | V52I | Q148* | A180T | V183D | E205G | L228F | P238S | A251T | S277T | T288M | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | M | E | V | Q | A | V | E | L | P | A | S | T | 42.40 | 0.289 |
| 2 | M | E | V | Q | A | V | G | F | P | A | S | T | 22.81 | 0.289 |
| 3 | M | E | V | Q | T | V | G | F | P | A | S | T | 19.74 | 0.289 |
| 4 | M | E | V | Q | A | V | G | L | P | A | S | T | 4.84 | 0.289 |
| 5 | M | E | V | Q | A | V | G | F | P | T | S | T | 2.92 | 0.289 |
| 6 | V | E | V | Q | A | V | E | L | P | A | S | T | 2.61 | 0.289 |
| 7 | M | E | V | Q | A | V | G | L | P | A | S | M | 1.15 | 0.289 |
| 8 | M | E | V | Q | A | V | G | L | S | A | S | T | 1.08 | 0.289 |
| 9 | M | E | I | Q | A | V | E | L | P | A | S | T | 0.69 | 0.289 |
| 10 | M | E | V | * | A | V | E | L | P | A | S | T | 0.61 | 1.200 |
| 11 | M | K | V | Q | A | V | E | L | P | A | T | T | 0.46 | 0.289 |
| 12 | M | K | V | Q | A | V | E | L | P | A | S | T | 0.31 | 0.289 |
| 13 | M | E | V | Q | T | V | G | L | P | A | S | T | 0.31 | 0.289 |
| 14 | M | E | V | Q | T | D | G | F | P | A | S | T | 0.08 | 0.289 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10R2.aApr07-unspliced | main_exon | 5UTR | chr1 | 158,479,878 | 158,479,911 | + |
| CDS | chr1 | 158,479,911 | 158,480,882 | + | ||
| 3UTR | chr1 | 158,480,882 | 158,480,885 | + | ||