OR10T2 Olfactory Receptor
| Gene Symbol | OR10T21 (View this gene in GeneCards) |
| Family | 10 |
| Subfamily | T |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | OR1-3, HsOR1.4.1, ORL3011 |
| External Ids | HGNC: 14816 GeneBank: AB065643, BK004364, NM_001004475 ORDB: ORL3011 |
| Build #39 labels | OR10T2 |
| Chromosomal location | 1:158,398,525-158,399,466 (-) |
| Cluster | 1@159a |
| Synteny | CLIC#4 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10R2 | 59.93% | 307 |
| OR10R3P | 59.4% | 298 |
| OR10T1P | 63.07% | 306 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR10T1 | 66% | 307 |
| Mouse | Or10b1-ps | 57% | 303 |
| Rat | Or10j2 | 56% | 300 |
| Cow | OR10T1 | 63% | 313 |
| Orang | OR10T2P | 93% | 314 |
| Horse | OR10R2C | 61% | 307 |
| Chimp | OR10T1P | 62% | 313 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB528820 |
Sequence information
| Nucleotide sequence |
ATGCGAGGTTTCAACAAAACCACTGTGGTTACACAGTTCATCCTGGTGGGTTTCTCCAGC CTGGGGGAGCTCCAGCTGCTGCTTTTTGTCATCTTTCTTCTCCTATACTTGACAATCCTG GTGGCCAATGTGACCATCATGGCCGTTATTCGCTTCAGCTGGACTCTCCACACTCCCATG TATGGCTTTCTATTCATCCTTTCATTTTCTGAGTCCTGCTACACTTTTGTCATCATCCCT CAGCTGCTGGTCCACCTGCTCTCAGACACCAAGACCATCTCCTTCATGGCCTGTGCCACC CAGCTGTTCTTTTTCCTTGGCTTTGCTTGCACCAACTGCCTCCTCATTGCTGTGATGGGA TATGATCGCTATGTAGCAATTTGTCACCCTCTGAGGTACACACTCATCATAAACAAAAGG CTGGGGTTGGAGTTGATTTCTCTCTCAGGAGCCACAGGTTTCTTTATTGCTTTGGTGGCC ACCAACCTCATTTGTGACATGCGTTTTTGTGGCCCCAACAGGGTTAACCACTATTTCTGT GACATGGCACCTGTTATCAAGTTAGCCTGCACTGACACCCATGTGAAAGAGCTGGCTTTA TTTAGCCTCAGCATCCTGGTAATTATGGTGCCTTTTCTGTTAATTCTCATATCCTATGGC TTCATAGTTAACACCATCCTGAAGATCCCCTCAGCTGAGGGCAAGAAGGCCTTTGTCACC TGTGCCTCACATCTCACTGTGGTCTTTGTCCACTATGGCTGTGCCTCTATCATCTATCTG CGGCCCAAGTCCAAGTCTGCCTCAGACAAGGATCAGTTGGTGGCAGTGACCTACACAGTG GTTACTCCCTTACTTAATCCTCTTGTCTACAGTCTGAGGAACAAAGAGGTAAAAACTGCA TTGAAAAGAGTTCTTGGAATGCCTGTGGCAACCAAGATGAGC |
| Conceptual translation |
MRGFNKTTVVTQFILVGFSSLGELQLLLFVIFLLLYLTILVANVTIMAVIRFSWTLHTPM YGFLFILSFSESCYTFVIIPQLLVHLLSDTKTISFMACATQLFFFLGFACTNCLLIAVMG YDRYVAICHPLRYTLIINKRLGLELISLSGATGFFIALVATNLICDMRFCGPNRVNHYFC DMAPVIKLACTDTHVKELALFSLSILVIMVPFLLILISYGFIVNTILKIPSAEGKKAFVT CASHLTVVFVHYGCASIIYLRPKSKSASDKDQLVAVTYTVVTPLLNPLVYSLRNKEVKTA LKRVLGMPVATKMS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | A/G | V/A | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | G/A | S/S | 1000GP (YRI, YRI) |
| 1 | 158,368,321 | 158,368,321 | NS | C/G | K/N | rs6692949 (DbSNP) |
| 1 | 158,368,392 | 158,368,392 | NS | C/T | V/I | rs61818748 (DbSNP) |
| 1 | 158,368,541 | 158,368,541 | NS | A/G | V/A | rs34465440 (DbSNP) |
| 1 | 158,368,794 | 158,368,794 | NS | A/G | F/L | rs12062580 (DbSNP) |
| 1 | 158,368,846 | 158,368,846 | NS | C/T | M/I | rs6662382 (DbSNP) |
| 1 | 158,368,915 | 158,368,915 | SYN | G/T | L/L | rs56704148 (DbSNP) |
| 1 | 158,368,964 | 158,368,964 | NS | C/T | C/Y | rs61818749 (DbSNP) |
| 1 | 158,368,974 | 158,368,974 | NS | A/G | F/L | rs61818750 (DbSNP) |
| 1 | 158,369,025 | 158,369,025 | NS | C/T | V/I | rs6662597 (DbSNP) |
| 1 | 158,369,064 | 158,369,064 | NS | A/G | F/L | rs41488350 (DbSNP) |
| 1 | 158,369,210 | 158,369,210 | NS | A/G | V/A | rs6660222 (DbSNP) |
| 1 | 158,398,525 | 158,398,525 | SYN | G/A | S/S | 1000GP (CEU, CHBJPT) |
| 1 | 158,398,566 | 158,398,566 | SYN | A/G | L/L | 1000GP (CEU) |
| 1 | 158,398,602 | 158,398,602 | NS | C/T | V/I | 1000GP (CEU) |
| 1 | 158,398,751 | 158,398,751 | NS | A/G | V/A | 1000GP (CEU, CHBJPT) |
| 1 | 158,399,056 | 158,399,056 | NS | T/C | I/M | 1000GP (CEU, CHBJPT) |
| 1 | 158,399,174 | 158,399,174 | NS | C/T | C/Y | 1000GP (CEU, CHBJPT) |
| 1 | 158,399,184 | 158,399,184 | NS | A/G | F/L | 1000GP (CEU, CHBJPT) |
| 1 | 158,399,274 | 158,399,274 | NS | A/G | F/L | 1000GP (CEU, CHBJPT) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| K312N | V289I | V239A | D181H | R168H | F155L | I137M | C98Y | F95L | I78V | F65L | N43S | V16A | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | K | V | V | D | R | F | I | C | F | I | F | N | V | 62.29 | 0.474 |
| 2 | K | V | A | D | R | F | M | C | F | I | F | N | V | 19.97 | 0.389 |
| 3 | K | V | A | D | R | F | M | Y | L | I | L | N | V | 9.45 | 0.981 |
| 4 | K | I | V | D | R | F | I | C | F | I | F | N | V | 2.15 | 0.474 |
| 5 | K | V | V | D | R | L | I | C | F | I | F | N | V | 1.84 | 0.474 |
| 6 | K | V | A | D | R | F | M | C | F | V | F | N | A | 0.69 | 0.389 |
| 7 | K | V | A | D | R | F | M | C | F | I | F | N | A | 0.69 | 0.389 |
| 8 | K | V | A | D | R | F | M | C | L | I | L | N | V | 0.54 | 0.389 |
| 9 | N | V | A | D | R | F | M | C | F | I | F | N | V | 0.54 | 0.389 |
| 10 | K | V | A | D | R | F | M | C | F | I | F | S | V | 0.46 | 1.000 |
| 11 | K | V | A | D | R | F | M | C | F | I | L | N | V | 0.38 | 0.389 |
| 12 | K | V | A | H | R | F | M | C | F | I | F | N | V | 0.31 | 0.389 |
| 13 | K | V | V | D | R | F | M | C | F | I | F | N | V | 0.23 | 0.389 |
| 14 | K | V | A | D | R | F | M | Y | L | I | F | N | V | 0.23 | 0.981 |
| 15 | K | V | V | D | H | F | I | C | F | I | F | N | V | 0.08 | 0.474 |
| 16 | K | I | V | D | R | L | I | C | F | I | F | N | V | 0.08 | 0.474 |
| 17 | K | V | V | D | R | F | I | C | F | I | L | N | V | 0.08 | 0.474 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR10T2.aApr07-unspliced | main_exon | 3UTR | chr1 | 158,398,522 | 158,398,525 | - |
| CDS | chr1 | 158,398,525 | 158,399,466 | - | ||