OR11A1 Olfactory Receptor
| Gene Symbol | OR11A11 (View this gene in GeneCards) |
| Family | 11 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.04 (functional) |
| Aliases | hs6M1-18, AC004174-A, dJ994E9.6, OR6-30, HsOR6.3.21, ORL524 |
| External Ids | HGNC: 8176 GeneBank: BK004208, HSA302614-HSA302623 ORDB: ORL524 |
| Build #39 labels | OR11A1 |
| Chromosomal location | 6:29,426,697-29,427,641 (-) |
| Cluster | 6@29 |
| Synteny | CLIC#12 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10U1P | 45.33% | 300 |
| OR11I1P | 47.73% | 308 |
| OR6B2 | 45.7% | 302 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR11I1 | 52% | 311 |
| Mouse | Or11a4 | 75% | 312 |
| Rat | Or11a4 | 74% | 312 |
| Cow | OR11A12 | 79% | 315 |
| Orang | OR11I1P | 46% | 314 |
| Horse | OR11E1P | 58% | 316 |
| Chimp | OR11I1P | 48% | 308 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | AA936177 |
| mRNA | BC131608 |
| GNF Atlas2 | 221343_at |
Sequence information
| Nucleotide sequence |
ATGGAAATTGTCTCCACAGGAAACGAAACTATTACTGAATTTGTCCTCCTTGGCTTCTAT GACATCCCTGAACTGCATTTCTTGTTTTTTATTGTATTCACTGCTGTCTATGTCTTCATC ATCATAGGGAATATGCTGATTATTGTAGCAGTGGTTAGCTCCCAGAGGCTCCACAAACCC ATGTATATTTTCTTGGCGAATCTGTCCTTCCTGGATATTCTCTACACCTCCGCAGTGATG CCAAAAATGCTGGAGGGCTTCCTGCAAGAAGCAACTATCTCTGTGGCTGGTTGCTTGCTC CAGTTCTTTATCTTCGGCTCTCTAGCCACAGCTGAATGCTTACTGCTGGCTGTCATGGCA TATGACCGCTACCTGGCAATTTGCTACCCACTCCACTACCCACTCCTGATGGGGCCCAGA CGGTACATGGGGCTGGTGGTCACAACCTGGCTCTCTGGATTTGTGGTAGATGGACTGGTT GTGGCCCTGGTGGCCCAGCTGAGGTTCTGTGGCCCCAACCACATTGACCAGTTTTACTGT GACTTTATGCTTTTCGTGGGCCTGGCTTGCTCGGATCCCAGAGTGGCTCAGGTGACAACT CTCATTCTGTCTGTGTTCTGCCTCACTATTCCTTTTGGACTGATTCTGACATCTTATGCC AGAATTGTGGTGGCAGTGCTGAGAGTTCCTGCTGGGGCAAGCAGGAGAAGGGCTTTCTCC ACATGCTCCTCCCACCTAGCTGTAGTGACCACATTCTATGGAACGCTCATGATCTTTTAT GTTGCACCCTCTGCTGTCCATTCCCAGCTCCTCTCCAAGGTCTTCTCCCTGCTCTACACT GTGGTCACCCCTCTCTTCAATCCTGTGATCTATACCATGAGGAACAAGGAGGTGCATCAG GCACTTCGGAAGATTCTCTGTATCAAACAAACTGAAACACTTGAT |
| Conceptual translation |
MEIVSTGNETITEFVLLGFYDIPELHFLFFIVFTAVYVFIIIGNMLIIVAVVSSQRLHKP MYIFLANLSFLDILYTSAVMPKMLEGFLQEATISVAGCLLQFFIFGSLATAECLLLAVMA YDRYLAICYPLHYPLLMGPRRYMGLVVTTWLSGFVVDGLVVALVAQLRFCGPNHIDQFYC DFMLFVGLACSDPRVAQVTTLILSVFCLTIPFGLILTSYARIVVAVLRVPAGASRRRAFS TCSSHLAVVTTFYGTLMIFYVAPSAVHSQLLSKVFSLLYTVVTPLFNPVIYTMRNKEVHQ ALRKILCIKQTETLD Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 6 | 29,395,057 | 29,395,057 | NS | C/T | C/Y | rs16894898 (DbSNP) |
| 6 | 29,394,926 | 29,394,926 | NS | C/T | A/T | rs9257857 (DbSNP) |
| 6 | 29,395,180 | 29,395,180 | NS | G/A | T/M | rs61978565 (DbSNP) |
| 6 | 29,394,889 | 29,394,889 | NS | T/C | Q/R | rs61742822 (DbSNP) |
| 6 | 29,395,104 | 29,395,104 | SYN | A/G | F/F | rs16894899 (DbSNP) |
| 6 | 29,395,044 | 29,395,044 | SYN | C/T | L/L | rs62408574 (DbSNP) |
| 6 | 29,427,149 | 29,427,149 | NS | C/T | A/T | 1000GP (CEU, CHBJPT) |
| 6 | 29,427,280 | 29,427,280 | NS | T/C | Y/C | 1000GP (CHBJPT) |
| 6 | 100 | -100 | NS | C/T | A/T | 1000GP (YRI, YRI, YRI) |
| 6 | 100 | -100 | SYN | G/A | F/F | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 4 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| A165T | D157A | Y121C | M80T | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | A | D | Y | M | 81.64 | 0.096 |
| 2 | T | D | Y | M | 10.06 | 0.096 |
| 3 | A | D | Y | T | 4.76 | 0.096 |
| 4 | A | D | C | M | 3.46 | 0.096 |
| 5 | A | A | Y | M | 0.08 | 0.096 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR11A1andOR5V1.aApr07 | main_exon | 3UTR | chr6 | 29,425,504 | 29,426,697 | - |
| CDS | chr6 | 29,426,697 | 29,427,641 | - | ||
| 5UTR | chr6 | 29,427,641 | 29,427,732 | - | ||
| exon_5UTR | chr6 | 29,428,913 | 29,428,960 | - | ||
| exon_5UTR | chr6 | 29,430,301 | 29,430,425 | - | ||
| exon_5UTR | chr6 | 29,431,864 | 29,431,987 | - | ||
| exon_5UTR | chr6 | 29,456,987 | 29,457,071 | - | ||