OR11H6 Olfactory Receptor
| Gene Symbol | OR11H61 (View this gene in GeneCards) |
| Family | 11 |
| Subfamily | H |
| Pseudogene | No |
| CORP pseudogene probability score | 0.08 (functional) |
| Aliases | OR14-35, HsOR14.1.27, ORL3699 |
| External Ids | HGNC: 15349 GeneBank: AB065889, BK004454, NM_001004480 ORDB: ORL3699 |
| Build #39 labels | OR11H6 |
| Chromosomal location | 14:20,223,779-20,224,699 (+) |
| Cluster | 14@20b |
| Synteny | CLIC#32 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR11H2 | 66.89% | 299 |
| OR11H4 | 68.4% | 307 |
| OR11H5P | 68.35% | 297 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR11H4 | 70% | 308 |
| Mouse | Or11h6 | 84% | 307 |
| Rat | Or11h6 | 86% | 290 |
| Cow | OR11H4 | 72% | 307 |
| Orang | OR11H4 | 69% | 307 |
| Horse | OR11H29P | 74% | 308 |
| Chimp | OR11H4 | 69% | 307 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB529290 |
| GNF Atlas2 | gnf1h02182_at |
Sequence information
| Nucleotide sequence |
ATGCATTTTGTGACTGAGTTTGTCCTCCTGGGTTTCCATGGTCAAAGGGAGATGCAGAGC TGCTTCTTCTCATTCATCCTGGTTCTCTATCTCCTGACACTGCTAGGGAATGGAGCTATT GTCTGTGCAGTGAAATTGGACAGGCGGCTCCACACACCCATGTACATCCTTCTGGGAAAC TTTGCCTTTCTAGAGATCTGGTACATTTCCTCCACTGTCCCAAACATGCTAGTCAATATC CTCTCTGAGATTAAAACCATCTCCTTCTCTGGTTGCTTCCTGCAATTCTATTTCTTTTTT TCACTGGGTACAACAGAGTGTTTCTTTTTATCAGTTATGGCTTATGATCGGTACCTGGCC ATCTGTCGTCCATTACACTACCCCTCCATCATGACTGGGAAGTTCTGTATAATTCTGGTC TGTGTATGCTGGGTAGGCGGATTTCTCTGCTATCCAGTCCCTATTGTTCTTATCTCCCAA CTTCCCTTCTGTGGGCCCAACATCATTGACCACTTGGTGTGTGACCCAGGCCCATTGTTT GCACTGGCCTGCATCTCTGCTCCTTCCACTGAGCTTATCTGTTACACCTTCAACTCGATG ATTATCTTTGGGCCCTTCCTCTCCATCTTGGGATCTTACACTCTGGTCATCAGAGCTGTG CTTTGTATTCCCTCTGGTGCTGGTCGAACTAAAGCTTTCTCCACATGTGGGTCCCACCTA ATGGTGGTGTCTCTATTCTATGGAACCCTTATGGTGATGTATGTGAGCCCAACATCAGGG AACCCAGCAGGAATGCAGAAGATCATCACTCTGGTATACACAGCAATGACTCCATTCTTA AATCCCCTTATCTATAGTCTTCGAAACAAAGACATGAAAGATGCTCTAAAGAGAGTCCTG GGGTTAACAGTTAGCCAAAAC |
| Conceptual translation |
MHFVTEFVLLGFHGQREMQSCFFSFILVLYLLTLLGNGAIVCAVKLDRRLHTPMYILLGN FAFLEIWYISSTVPNMLVNILSEIKTISFSGCFLQFYFFFSLGTTECFFLSVMAYDRYLA ICRPLHYPSIMTGKFCIILVCVCWVGGFLCYPVPIVLISQLPFCGPNIIDHLVCDPGPLF ALACISAPSTELICYTFNSMIIFGPFLSILGSYTLVIRAVLCIPSGAGRTKAFSTCGSHL MVVSLFYGTLMVMYVSPTSGNPAGMQKIITLVYTAMTPFLNPLIYSLRNKDMKDALKRVL GLTVSQN Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 14 | 20,692,305 | 20,692,305 | NS | A/G | H/R | rs17106351 (DbSNP) |
| 14 | 20,692,595 | 20,692,595 | NS | C/G | L/V | rs61993884 (DbSNP) |
| 14 | 20,691,962 | 20,691,962 | NS | C/G | L/V | rs9323693 (DbSNP) |
| 14 | 20,692,188 | 20,692,188 | NS | C/T | T/I | rs12891553 (DbSNP) |
| 14 | 20,692,643 | 20,692,643 | NS | C/T | R/C | rs17277228 (DbSNP) |
| 14 | 20,692,574 | 20,692,574 | NS | C/T | H/Y | rs17277221 (DbSNP) |
| 14 | 20,692,453 | 20,692,453 | NS | G/T | L/F | rs17211285 (DbSNP) |
| 14 | 20,692,291 | 20,692,291 | SYN | C/T | Y/Y | rs34693535 (DbSNP) |
| 14 | 20,224,294 | 20,224,294 | NS | G/T | L/F | 1000GP (CEU, CHBJPT) |
| 14 | 20,224,415 | 20,224,415 | NS | T/C | Y/H | 1000GP (CEU, CHBJPT) |
| 14 | 20,224,436 | 20,224,436 | NS | G/C | V/L | 1000GP (CEU) |
| 14 | 20,224,484 | 20,224,484 | NS | T/C | C/R | 1000GP (CEU, CHBJPT) |
| 14 | 20,224,029 | 20,224,029 | NS | T/C | I/T | 1000GP (CEU, CHBJPT) |
| 14 | 20,223,803 | 20,223,803 | NS | C/G | L/V | 1000GP (CEU, CHBJPT) |
| 14 | 20,224,132 | 20,224,132 | SYN | C/T | Y/Y | 1000GP (CEU, CHBJPT) |
| 14 | 100 | -100 | NS | C/G | L/V | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
| 14 | 100 | -100 | SYN | C/T | Y/Y | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 14 | 20,203,125 | 20,716,841 | CopyNumber | Variation_8765 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| L32V | G59E | I107T | R146H | G156R | L195F | Y236H | V243L | C259R | T297R | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | L | G | I | R | G | L | Y | V | C | T | 41.32 | 0.424 |
| 2 | L | G | T | R | G | F | H | V | R | T | 33.49 | 0.424 |
| 3 | V | G | I | R | G | L | Y | V | C | T | 10.29 | 0.424 |
| 4 | L | G | I | H | G | L | Y | V | C | T | 8.91 | 0.424 |
| 5 | L | G | T | R | G | F | H | L | R | T | 4.76 | 0.574 |
| 6 | L | G | T | R | G | F | H | V | C | T | 0.23 | 0.424 |
| 7 | L | E | T | R | G | F | H | V | R | T | 0.15 | 0.424 |
| 8 | L | G | I | R | G | F | H | V | R | T | 0.15 | 0.424 |
| 9 | L | G | T | R | G | L | H | V | R | T | 0.15 | 0.424 |
| 10 | L | G | T | R | G | F | H | V | R | R | 0.15 | 0.424 |
| 11 | L | G | T | R | R | F | H | V | R | T | 0.08 | 0.424 |
| 12 | L | G | I | R | G | F | Y | V | C | T | 0.08 | 0.424 |
| 13 | L | G | T | R | G | F | Y | V | R | T | 0.08 | 0.424 |
| 14 | L | G | T | R | G | F | Y | V | C | T | 0.08 | 0.424 |
| 15 | L | G | I | R | G | L | Y | L | R | T | 0.08 | 0.574 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR11H6.aApr07-unspliced | main_exon | 5UTR | chr14 | 20,223,710 | 20,223,779 | + |
| CDS | chr14 | 20,223,779 | 20,224,699 | + | ||
| 3UTR | chr14 | 20,224,699 | 20,224,702 | + | ||