OR14C36 Olfactory Receptor
| Gene Symbol | OR14C361 (View this gene in GeneCards) |
| Family | 14 |
| Subfamily | C |
| Pseudogene | No |
| CORP pseudogene probability score | 0 (functional) |
| Aliases | HsOR1.5.36 |
| External Ids | HGNC: 15026 |
| Build #39 labels | OR5BF1 |
| Chromosomal location | 1:248,348,775-248,349,710 (+) |
| Cluster | 1@248 |
| Synteny | CLIC#0 |
| Remarks | Belongs to OR14- a new family which is expanded in opossum and platypus. Was previously classified into family 5 with the symbol OR5BF1. |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR10A2 | 74.66% | 296 |
| OR14A16 | 50% | 304 |
| OR14I1 | 49.35% | 308 |
| OR14J1 | 46.89% | 305 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR14I2 | 48% | 306 |
| Mouse | Or14c39 | 61% | 305 |
| Rat | Or14c39 | 60% | 309 |
| Cow | OR14P2 | 49% | 304 |
| Orang | OR14C36BP | 92% | 310 |
| Horse | OR14C53 | 64% | 309 |
| Chimp | OR14I1 | 49% | 311 |
Expression evidences
| Source | Accession |
|---|---|
| GNF Atlas2 | gnf1h10659_at |
Sequence information
| Nucleotide sequence |
ATGCCCAATTCAACCACCGTGATGGAATTTCTCCTCATGAGGTTTTCTGATGTGTGGACA CTACAGATTTTACATTCTGCATCCTTCTTTATGTTGTATTTGGTAACTCTAATGGGAAAC ATCCTCATTGTGACCGTCACCACCTGTGACAGCAGCCTTCACATGCCCATGTACTTCTTC CTCAGGAATCTGTCTATCTTGGATGCCTGCTACATTTCTGTTACAGTCCCTACCTCATGT GTCAATTCCCTACTGGACAGCACCACCATTTCTAAGGCGGGATGTGTAGCTCAGGTCTTC CTCGTGGTTTTTTTTGTATATGTGGAGCTTCTGTTTCTCACCATTATGGCTCATGACCGC TATGTGGCTGTCTGCCAGCCACTTCACTACCCTGTGATCGTGAACTCTCGAATCTGCATC CAGATGACACTGGCCTCCCTACTCAGTGGTCTTGTCTATGCAGGCATGCACACTGGCAGC ACATTCCAGCTGCCCTTCTGTCGGTCCAACGTTATTCATCAATTCTTCTGTGACATCCCC TCTCTGCTGAAGCTCTCTTGCTCTGACACCTTCAGCAATGAGGTCATGATTGTTGTCTCT GCTCTGGGGGTAGGTGGCGGCTGTTTCATCTTTATCATCAGGTCTTACATTCACATCTTT TCGACCGTGCTCGGGTTTCCAAGAGGAGCAGACAGAACAAAGGCCTTTTCCACCTGCATC CCTCACATCCTGGTGGTGTCAGTCTTCCTCAGTTCATGCTCTTCTGTGTACCTCAGGCCA CCTGCGATACCTGCAGCCACCCAGGATCTGATCCTTTCTGGTTTTTATTCCATAATGCCT CCCCTCTTTAACCCTATTATTTACAGTCTTAGAAATAAGCAAATAAAGGTGGCCATCAAG AAAATCATGAAGAGAATTTTTTATTCAGAAAATGTG |
| Conceptual translation |
MPNSTTVMEFLLMRFSDVWTLQILHSASFFMLYLVTLMGNILIVTVTTCDSSLHMPMYFF LRNLSILDACYISVTVPTSCVNSLLDSTTISKAGCVAQVFLVVFFVYVELLFLTIMAHDR YVAVCQPLHYPVIVNSRICIQMTLASLLSGLVYAGMHTGSTFQLPFCRSNVIHQFFCDIP SLLKLSCSDTFSNEVMIVVSALGVGGGCFIFIIRSYIHIFSTVLGFPRGADRTKAFSTCI PHILVVSVFLSSCSSVYLRPPAIPAATQDLILSGFYSIMPPLFNPIIYSLRNKQIKVAIK KIMKRIFYSENV Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | A/G | Q/R | 1000GP (YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | C/T | T/T | 1000GP (YRI, YRI, YRI) |
| 1 | 248,348,792 | 248,348,792 | SYN | C/T | T/T | 1000GP (CEU, CHBJPT) |
| 1 | 248,349,196 | 248,349,196 | NS | A/G | Q/R | 1000GP (CEU, CHBJPT) |
| 1 | 248,349,335 | 248,349,335 | SYN | C/T | C/C | 1000GP (CEU, CHBJPT) |
| 1 | 248,349,447 | 248,349,447 | NS | G/A | G/R | 1000GP (CEU, CHBJPT) |
| 1 | 248,349,465 | 248,349,465 | NS | G/T | D/Y | 1000GP (CEU, CHBJPT) |
| 1 | 248,512,094 | 248,512,094 | SNP | C/T | rs28728105 (DbSNP) | |
| 1 | 248,512,498 | 248,512,498 | SNP | A/G | rs28448343 (DbSNP) | |
| 1 | 248,512,637 | 248,512,637 | SNP | T/C | rs2039824 (DbSNP) | |
| 1 | 248,512,684 | 248,512,684 | SNP | C/G | rs62621369 (DbSNP) | |
| 1 | 248,512,749 | 248,512,749 | SNP | A/G | rs28377739 (DbSNP) | |
| 1 | 248,512,767 | 248,512,767 | SNP | G/T | rs28545014 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 248,060,959 | 249,167,690 | CopyNumber | Variation_8354 (DGV) |
| 1 | 248,242,528 | 248,817,382 | CopyNumber | Variation_8935 (DGV) |
| 1 | 248,500,109 | 248,865,374 | CopyNumber | Variation_3340 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| Q141R | G225R | D231Y | R305I | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | Q | R | Y | R | 41.55 | 0.021 |
| 2 | Q | G | D | R | 33.41 | 0.021 |
| 3 | R | G | D | R | 22.81 | 0.021 |
| 4 | Q | R | Y | I | 1.77 | 0.021 |
| 5 | R | G | Y | R | 0.15 | 0.021 |
| 6 | R | R | Y | R | 0.15 | 0.021 |
| 7 | Q | G | D | I | 0.08 | 0.021 |
| 8 | R | R | D | R | 0.08 | 0.021 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5BF1.aApr07-unspliced | main_exon | CDS | chr1 | 248,348,775 | 248,349,710 | + |
| 3UTR | chr1 | 248,349,710 | 248,349,713 | + | ||