OR2B2 Olfactory Receptor
Gene Symbol | OR2B21 (View this gene in GeneCards) |
Family | 2 |
Subfamily | B |
Pseudogene | No |
CORP pseudogene probability score | |
Aliases | OR6-2, OR6-1, dJ193B12.4, HsOR6.2.1, ORL681, ORL680, ORL1019 |
External Ids | HGNC: 13966 GeneBank: BK004361, HSA302584-HSA302593, NM_033057 ORDB: ORL681, ORL680, ORL1019 |
Build #39 labels | OR2B2 |
Chromosomal location | 6:27,911,249-27,912,319 (-) |
Cluster | 6@28a |
Synteny | CLIC#12 |
Remarks |
Most Similar ORs in Humans (Paralogs)
Symbol | Percent | Length |
---|---|---|
OR2B6 | 81.61% | 310 |
Most Similar ORs in other species (Orthologs)
Specie | Symbol | Percent | Length |
---|---|---|---|
Dog | OR2B10P | 72% | 303 |
Mouse | Or2b2 | 86% | 313 |
Mouse | Or2b2b | 86% | 313 |
Rat | Or2b2 | 84% | 310 |
Cow | OR2B2D | 85% | 314 |
Orang | OR2B6 | 81% | 313 |
Horse | OR2B6 | 82% | 313 |
Chimp | OR2B2P | 96% | 313 |
Expression evidences
Source | Accession |
---|---|
ESTs | N68399 |
mRNA | BC136901 |
GNF Atlas2 | 216408_at |
Sequence information
Nucleotide sequence |
ATGAATTGGGTAAATAAGAGTGTCCCACAGGAGTTCATTCTGTTAGTTTTCTCAGATCAA CCATGGCTAGAGATTCCACCCTTTGTGATGTTTCTGTTTTCCTATATCTTGACAATCTTT GGCAATCTGACAATAATTCTTGTGTCACATGTGGATTTCAAACTCCACACCCCTATGTAC TTTTTTCTTAGCAATCTCTCACTCCTGGACCTTTGCTATACCACAAGTACAGTTCCACAA ATGCTGGTAAACATATGCAACACCAGGAAAGTAATCAGTTATGGTGGCTGTGTGGCCCAG CTTTTCATTTTCCTGGCCTTGGGTTCCACAGAATGTCTTCTCCTGGCCGTCATGTGCTTT GATAGGTTTGTAGCTATTTGTCGGCCTCTCCATTACTCAATTATCATGCACCAGAGGCTC TGCTTCCAGTTGGCAGCTGCATCCTGGATTAGTGGCTTTAGCAATTCAGTATTACAGTCC ACCTGGACACTTAAGATGCCACTGTGTGGTCACAAAGAAGTGGATCACTTCTTCTGTGAA GTCCCTGCTCTGCTCAAGTTGTCCTGTGTTGACACAACAGCAAATGAGGCTGAACTATTC TTCATCAGTGTGCTATTCCTTCTAATACCCGTGACACTCATCCTTATATCGTATGCTTTT ATTGTCCAAGCAGTGTTGAGAATCCAGTCTGCTGAAGGTCAACGAAAGGCATTTGGGACA TGTGGCTCCCATCTAATTGTGGTGTCACTTTTTTATGGTACAGCTATCTCCATGTACCTG CAACCACCTTCACCCAGCTCCAAAGACCGGGGAAAGATGGTTTCTCTCTTCTGTGGAATC ATTGCACCCATGCTGAATCCCCTTATATATACACTTAGGAACAAAGAGGTAAAGGAAGCC TTTAAAAGGTTGGTTGCAAAGAGTCTTCTTAATCAAGAAATAAGAAATATGCAAATGATA AGCTTTGCTAAAGACACAGTGCTTACTTACCTTACTAACTTCTCCGCAAGTTGTCCTATT TTTGTCATTACTATAGAAAACTATTGTAATCTCCCTCAAAGAAAATTTCCT |
Conceptual translation |
MNWVNKSVPQEFILLVFSDQPWLEIPPFVMFLFSYILTIFGNLTIILVSHVDFKLHTPMY FFLSNLSLLDLCYTTSTVPQMLVNICNTRKVISYGGCVAQLFIFLALGSTECLLLAVMCF DRFVAICRPLHYSIIMHQRLCFQLAAASWISGFSNSVLQSTWTLKMPLCGHKEVDHFFCE VPALLKLSCVDTTANEAELFFISVLFLLIPVTLILISYAFIVQAVLRIQSAEGQRKAFGT CGSHLIVVSLFYGTAISMYLQPPSPSSKDRGKMVSLFCGIIAPMLNPLIYTLRNKEVKEA FKRLVAKSLLNQEIRNMQMISFAKDTVLTYLTNFSASCPIFVITIENYCNLPQRKFP Protein domains and features |
Variations - SNPs
Chr | Start | End | Type | Variation | AA Change | SNP IDs |
---|---|---|---|---|---|---|
6 | 27,879,200 | 27,879,200 | NS | A/C | S/A | rs34788973 (DbSNP) |
6 | 27,879,982 | 27,879,982 | NS | A/G | I/T | rs61742093 (DbSNP) |
6 | 27,879,551 | 27,879,551 | NS | C/G | A/P | rs9368537 (DbSNP) |
6 | 27,879,397 | 27,879,397 | NS | C/T | R/Q | rs34957169 (DbSNP) |
6 | 27,879,869 | 27,879,869 | NS | G/T | P/T | rs35712782 (DbSNP) |
6 | 27,879,093 | 27,879,093 | SYN | A/G | S/S | rs73392698 (DbSNP) |
6 | 27,911,773 | 27,911,773 | NS | C/G | A/P | 1000GP (CEU, CHBJPT) |
6 | 27,911,619 | 27,911,619 | NS | T/C | Q/R | 1000GP (CEU) |
6 | 27,911,422 | 27,911,422 | NS | C/A | A/S | 1000GP (CEU) |
6 | 27,912,204 | 27,912,204 | NS | A/G | I/T | 1000GP (CEU) |
6 | 27,911,670 | 27,911,670 | NS | G/A | S/L | 1000GP (CHBJPT) |
6 | 100 | -100 | SYN | G/A | S/S | 1000GP (YRI) |
6 | 100 | -100 | NS | T/C | Q/R | 1000GP (YRI, YRI) |
Variations - CNVs
Chr | Start | End | Type | Sources |
---|---|---|---|---|
CopyNumber | 68 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
Y348F | A300S | R270Q | Q234R | S217L | A183P | T77P | S76G | I39T | % Freq | CORP | |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | Y | A | R | Q | S | A | T | S | I | 87.17 | 0.449 |
2 | Y | A | R | Q | S | P | T | S | I | 4.61 | 0.449 |
3 | Y | S | R | Q | S | A | T | S | T | 3.61 | 0.449 |
4 | Y | A | R | R | S | A | T | S | I | 3.07 | 0.449 |
5 | Y | A | R | Q | L | P | T | S | I | 0.38 | 0.707 |
6 | Y | A | R | Q | S | A | P | S | I | 0.38 | 0.449 |
7 | F | A | R | Q | S | A | T | S | I | 0.31 | 0.449 |
8 | Y | A | Q | Q | S | A | T | S | I | 0.23 | 0.449 |
9 | Y | S | R | Q | S | A | T | S | I | 0.15 | 0.449 |
10 | Y | A | R | Q | S | A | T | G | I | 0.08 | 0.449 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
Accession | Type | Chr | Start | End | Strand | |
---|---|---|---|---|---|---|
OR2B2.aApr07-unspliced | main_exon | 3UTR | chr6 | 27,911,246 | 27,911,249 | - |
CDS | chr6 | 27,911,249 | 27,912,319 | - | ||
5UTR | chr6 | 27,912,319 | 27,912,558 | - |