OR2J2 Olfactory Receptor
| Gene Symbol | OR2J21 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | J |
| Pseudogene | No |
| CORP pseudogene probability score | 0.81 (pseudogene) |
| Aliases | OR6-19, OR6-8, hs6M1-6, dJ80I19.4, HsOR6.3.8, ORL682, ORL1032, ORL683, ORL684 |
| External Ids | HGNC: 8260 GeneBank: BC069121, BK004438, HSA302571-HSA302582, NM_030905 ORDB: ORL682, ORL1032, ORL683, ORL684 |
| Build #39 labels | OR2J2 |
| Chromosomal location | 6:29,173,636-29,174,571 (+) |
| Cluster | 6@29 |
| Synteny | CLIC#12 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2J1P | 91.59% | 309 |
| OR2J3 | 88.56% | 306 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2B2 | 61% | 305 |
| Mouse | Or2j3 | 81% | 307 |
| Rat | Or2j3 | 81% | 301 |
| Cow | OR2J1 | 88% | 307 |
| Cow | OR2J3 | 87% | 304 |
| Cow | OR2J3C | 86% | 307 |
| Cow | OR2J3B | 86% | 307 |
| Orang | OR2J1 | 89% | 311 |
| Horse | OR2J1B | 87% | 309 |
| Horse | OR2J1 | 87% | 310 |
| Horse | OR2J3 | 87% | 307 |
| Horse | OR2J3G | 85% | 309 |
| Chimp | OR2J1 | 91% | 311 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | BU182611 |
| mRNA | BC108899 |
| GNF Atlas2 | 208508_s_at |
Sequence information
| Nucleotide sequence |
ATGATGATTAAAAAAAATGCAAGTTCGGAAGACTTCTTTATTCTACTTGGATTTTCTAAT TGGCCTCAGCTGGAAGTAGTTCTCTTTGTGGTTATCTTGATCTTCTACCTGATGACACTG ACAGGAAACCTGTTCATCATCATCCTGTCATACGTGGACTCCCATCTCCACACACCAATG TACTTCTTCCTTTCAAACCTCTCATTTCTGGATCTCTGCCACACCACCAGCTCTATCCCT CAGTTGCTGGTGAATCTCCGGGGCCCGGAAAAGACCATCTCGTATGCTGGTTGCATGGTT CAACTTTACTTTGTTCTTGCACTGGGAATCGCAGAGTGTGTCCTACTGGTGGTGATGTCG TATGATCGTTATGTAGCTGTGTGTAGACCTTTGCATTACACTGTCCTCATGCACCCTCGT TTCTGCCACTTGTTGGCTGCGGCTTCTTGGGTAATTGGTTTTACTATCTCAGCACTTCAT TCCTCCTTTACTTTCTGGGTACCCCTTTGTGGACATCGCCTAGTGGATCACTTCTTCTGT GAAGTTCCAGCACTTCTGCGTTTATCATGTGTTGACACCCATGCAAATGAGCTGACCCTC ATGGTCATGAGCTCCATTTTTGTTCTCATACCTCTCATTCTGATTCTCACTGCCTATGGT GCCATTGCCCGGGCTGTACTGAGCATGCAATCAACCACTGGGCTTCAGAAAGTGTTTAGG ACATGTGGAGCCCATCTTATGGTTGTATCTCTCTTTTTCATTCCAGTCATGTGCATGTAT CTCCAGCCACCATCAGAAAATTCTCCTGATCAGGGCAAGTTCATTGCCCTCTTTTATACT GTTGTCACACCGAGTCTTAATCCTCTAATCTACACTCTCAGAAACAAGCATGTAAAAGGG GCAGCGAAGAGACTATTGGGGTGGGAGTGGGGGAAG |
| Conceptual translation |
MMIKKNASSEDFFILLGFSNWPQLEVVLFVVILIFYLMTLTGNLFIIILSYVDSHLHTPM YFFLSNLSFLDLCHTTSSIPQLLVNLRGPEKTISYAGCMVQLYFVLALGIAECVLLVVMS YDRYVAVCRPLHYTVLMHPRFCHLLAAASWVIGFTISALHSSFTFWVPLCGHRLVDHFFC EVPALLRLSCVDTHANELTLMVMSSIFVLIPLILILTAYGAIARAVLSMQSTTGLQKVFR TCGAHLMVVSLFFIPVMCMYLQPPSENSPDQGKFIALFYTVVTPSLNPLIYTLRNKHVKG AAKRLLGWEWGK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 6 | 29,141,449 | 29,141,448 | Ins(1) | -/T | rs72202226 (DbSNP) | |
| 6 | 29,141,743 | 29,141,743 | NS | A/G | T/A | rs3129157 (DbSNP) |
| 6 | 29,142,064 | 29,142,064 | NS | A/G | T/A | rs3130743 (DbSNP) |
| 6 | 29,142,347 | 29,142,347 | NS | A/T | K/M | rs41270632 (DbSNP) |
| 6 | 29,141,632 | 29,141,632 | NS | C/T | H/Y | rs3116855 (DbSNP) |
| 6 | 29,141,849 | 29,141,849 | NS | C/T | A/V | rs3116856 (DbSNP) |
| 6 | 29,142,020 | 29,142,020 | NS | C/T | T/M | rs62405964 (DbSNP) |
| 6 | 29,142,317 | 29,142,317 | NS | C/T | A/V | rs41270628 (DbSNP) |
| 6 | 29,141,772 | 29,141,772 | SYN | A/C/G | S/S | rs3129158 (DbSNP) |
| 6 | 29,142,030 | 29,142,030 | SYN | A/T | I/I | rs61733733 (DbSNP) |
| 6 | 29,142,054 | 29,142,054 | SYN | C/G | L/L | rs3129159 (DbSNP) |
| 6 | 29,173,966 | 29,173,966 | NS | A/G | T/A | 1000GP (CEU, CHBJPT) |
| 6 | 29,174,287 | 29,174,287 | NS | A/G | T/A | 1000GP (CEU, CHBJPT) |
| 6 | 29,174,072 | 29,174,072 | NS | T/C | V/A | 1000GP (CEU, CHBJPT) |
| 6 | 29,174,277 | 29,174,277 | SYN | C/G | L/L | 1000GP (CEU, CHBJPT) |
| 6 | 29,174,570 | 29,174,570 | NS | A/T | K/M | 1000GP (CEU, CHBJPT) |
| 6 | 29,173,995 | 29,173,995 | SYN | A/G | S/S | 1000GP (CEU, CHBJPT) |
| 6 | 29,174,540 | 29,174,540 | NS | C/T | A/V | 1000GP (CEU) |
| 6 | 100 | -100 | NS | C/A | A/E | 1000GP (YRI, YRI, YRI) |
| 6 | 100 | -100 | SYN | A/G | S/S | 1000GP (YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 6 | 29,099,579 | 29,149,561 | CopyNumber | Variation_51868 (DGV) |
| 6 | 29,091,539 | 29,163,849 | CopyNumber | Variation_64459 (DGV) |
| 6 | 29,141,313 | 29,144,348 | Deletion | #191 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| V52M | Y74H | R87Q | A107E | E112K | V146A | A195G | M203T | T218A | A302V | K312M | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | V | Y | R | A | E | V | A | M | T | A | K | 56.07 | 0.789 |
| 2 | V | H | R | A | E | A | A | M | A | A | K | 33.87 | 0.789 |
| 3 | V | Y | R | A | E | A | A | M | T | A | K | 3.76 | 0.789 |
| 4 | V | Y | R | A | E | V | A | M | T | A | M | 3.23 | 0.789 |
| 5 | V | Y | R | E | E | V | A | M | T | A | K | 0.84 | 0.789 |
| 6 | V | H | R | A | E | A | A | M | T | A | K | 0.38 | 0.789 |
| 7 | V | Y | R | A | E | V | A | M | T | V | K | 0.38 | 0.789 |
| 8 | V | H | R | A | E | V | A | M | A | A | K | 0.38 | 0.789 |
| 9 | V | H | R | A | E | V | A | M | T | A | K | 0.31 | 0.789 |
| 10 | V | Y | R | A | E | V | A | T | T | A | K | 0.23 | 0.789 |
| 11 | V | Y | R | A | K | V | A | M | T | A | K | 0.15 | 0.822 |
| 12 | V | Y | Q | A | E | V | A | M | T | A | K | 0.08 | 0.789 |
| 13 | V | Y | R | A | E | V | A | M | A | V | K | 0.08 | 0.789 |
| 14 | V | H | R | A | E | A | G | M | A | A | K | 0.08 | 0.789 |
| 15 | V | Y | R | A | E | A | A | M | A | A | K | 0.08 | 0.789 |
| 16 | M | Y | R | A | E | V | A | M | T | A | M | 0.08 | 0.789 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2J2.aApr07-unspliced | main_exon | 5UTR | chr6 | 29,173,303 | 29,173,636 | + |
| CDS | chr6 | 29,173,636 | 29,174,571 | + | ||
| 3UTR | chr6 | 29,174,571 | 29,174,574 | + | ||