OR2J3 Olfactory Receptor
| Gene Symbol | OR2J31 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | J |
| Pseudogene | No |
| CORP pseudogene probability score | 0.62 (pseudogene) |
| Aliases | OR6-6, hs6M1-3, dJ80I19.7, OR6-16, HsOR6.3.6, ORL692, ORL671 |
| External Ids | HGNC: 8261 GeneBank: AF399630, BK004437, HSA302547-HSA302558, NM_001005216 ORDB: ORL692, ORL671 |
| Build #39 labels | OR2J3 |
| Chromosomal location | 6:29,111,891-29,112,823 (+) |
| Cluster | 6@29 |
| Synteny | CLIC#12 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2J1P | 89.54% | 306 |
| OR2J2 | 88.56% | 306 |
| OR2J4P | 89.71% | 311 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2B2 | 62% | 304 |
| Mouse | Or2j3 | 83% | 304 |
| Rat | Or2j3 | 84% | 297 |
| Cow | OR2J3C | 91% | 304 |
| Cow | OR2J3D | 91% | 304 |
| Cow | OR2J3B | 89% | 304 |
| Orang | OR2J4P | 90% | 311 |
| Orang | OR2J1 | 90% | 306 |
| Horse | OR2J1 | 92% | 306 |
| Horse | OR2J3G | 91% | 306 |
| Horse | OR2J1B | 90% | 304 |
| Chimp | OR2J4P | 90% | 311 |
| Chimp | OR2J1 | 90% | 306 |
| Chimp | OR2J2 | 89% | 306 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136975 |
| GNF Atlas2 | 217334_at |
Sequence information
| Nucleotide sequence |
ATGAATGATGATGGAAAAGTCAATGCTAGCTCTGAGGGGTACTTTATTTTAGTTGGATTT TCTAATTGGCCTCATCTGGAAGTAGTTATCTTTGTGGTTGTCTTGATCTTCTACTTGATG ACACTGATAGGAAACCTGTTCATCATCATCCTGTCATACCTGGACTCCCATCTGCACACA CCAATGTACTTCTTCCTTTCAAACCTCTCATTTCTGGATCTCTGCTACACCACCAGCTCT ATCCCTCAGTTGCTGGTCAATCTCTGGGGCCCGGAAAAGACCATCTCTTATGCTGGTTGC ATGATTCAACTTTACTTTGTTCTCGCACTGGGAACCACAGAGTGTGTCCTACTGGTGGTG ATGTCCTATGACCGTTATGCAGCTGTGTGTAGACCTTTGCATTACACTGTCCTCATGCAC CCTCGTTTCTGCCACCTGCTGGCTGTGGCTTCTTGGGTAAGTGGTTTTACCAACTCAGCA CTTCATTCCTCCTTCACCTTCTGGGTACCTCTGTGTGGACACCGCCAAGTAGATCACTTT TTCTGTGAAGTTCCAGCACTTCTGCGATTATCGTGTGTTGATACCCATGTCAATGAGCTG ACCCTCATGATCACAAGCTCCATATTTGTTCTCATACCTCTCATCCTCATTCTCACTTCT TATGGTGCCATCGTCCGAGCTGTACTGAGGATGCAGTCAACCACTGGGCTTCAGAAAGTG TTTGGAACATGTGGAGCTCATCTTATGGCTGTATCTCTCTTTTTCATTCCGGCCATGTGC ATATATCTCCAGCCACCATCAGGAAATTCTCAAGATCAAGGCAAGTTCATTGCCCTCTTT TATACTGTTGTCACACCTAGTCTTAACCCTCTAATCTACACCCTCAGAAACAAAGTTGTA AGAGGGGCAGTGAAGAGACTAATGGGGTGGGAA |
| Conceptual translation |
MNDDGKVNASSEGYFILVGFSNWPHLEVVIFVVVLIFYLMTLIGNLFIIILSYLDSHLHT PMYFFLSNLSFLDLCYTTSSIPQLLVNLWGPEKTISYAGCMIQLYFVLALGTTECVLLVV MSYDRYAAVCRPLHYTVLMHPRFCHLLAVASWVSGFTNSALHSSFTFWVPLCGHRQVDHF FCEVPALLRLSCVDTHVNELTLMITSSIFVLIPLILILTSYGAIVRAVLRMQSTTGLQKV FGTCGAHLMAVSLFFIPAMCIYLQPPSGNSQDQGKFIALFYTVVTPSLNPLIYTLRNKVV RGAVKRLMGWE Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 6 | 29,080,349 | 29,080,349 | NS | A/G | I/V | rs3130764 (DbSNP) |
| 6 | 29,080,004 | 29,080,004 | NS | A/G | T/A | rs28757581 (DbSNP) |
| 6 | 29,080,450 | 29,080,450 | NS | A/G | I/M | rs3130765 (DbSNP) |
| 6 | 29,080,344 | 29,080,344 | NS | G/A | R/Q | rs3749977 (DbSNP) |
| 6 | 29,112,227 | 29,112,227 | NS | A/G | T/A | 1000GP (CEU, CHBJPT) |
| 6 | 29,112,609 | 29,112,609 | NS | T/C | V/A | 1000GP (CEU) |
| 6 | 29,112,673 | 29,112,673 | NS | G/A | M/I | 1000GP (CEU) |
| 6 | 29,112,567 | 29,112,567 | NS | G/A | R/Q | 1000GP (CEU, CHBJPT) |
| 6 | 29,112,572 | 29,112,572 | NS | A/G | I/V | 1000GP (CEU, CHBJPT) |
| 6 | 100 | -100 | NS | A/G | T/A | 1000GP (YRI, YRI, YRI, YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| A109T | T113A | V240A | M261I | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | A | T | V | I | 50.46 | 0.591 |
| 2 | A | T | V | M | 27.57 | 0.591 |
| 3 | A | A | V | I | 17.28 | 0.591 |
| 4 | A | A | A | I | 2.30 | 0.336 |
| 5 | T | T | V | I | 1.92 | 0.591 |
| 6 | A | T | A | I | 0.46 | 0.336 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2J3.aApr07-unspliced | main_exon | 5UTR | chr6 | 29,111,560 | 29,111,891 | + |
| CDS | chr6 | 29,111,891 | 29,112,823 | + | ||
| 3UTR | chr6 | 29,112,823 | 29,112,826 | + | ||