OR2M2 Olfactory Receptor
| Gene Symbol | OR2M21 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | M |
| Pseudogene | No |
| CORP pseudogene probability score | 0.04 (functional) |
| Aliases | OST423, HsOR1.5.30, ORL3817 |
| External Ids | HGNC: 8268 GeneBank: AF399616, NM_001004688 ORDB: ORL3817 |
| Build #39 labels | OR2M2 |
| Chromosomal location | 1:248,179,986-248,181,026 (+) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2M3 | 92.26% | 310 |
| OR2M5 | 91.26% | 309 |
| OR2M7 | 92.26% | 310 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2M10P | 79% | 312 |
| Mouse | Or2m12 | 74% | 310 |
| Rat | Or2m12 | 75% | 307 |
| Cow | OR2M10 | 77% | 310 |
| Orang | OR2M5P | 90% | 312 |
| Orang | OR2M3P | 91% | 307 |
| Horse | OR2M27 | 75% | 323 |
| Chimp | OR2M7 | 93% | 310 |
| Chimp | OR2M3 | 93% | 310 |
| Chimp | OR2M5 | 90% | 308 |
Sequence information
| Nucleotide sequence |
ATGGCATGGGAGAATCAGACCTTCAACTCCGACTTCATCCTCCTTGGAATCTTCAATCAC AGCCCACCACACACGTTCCTCTTCTTTCTGGTCCTGGGCATCTTTTTAGTGGCCTTCATG GGAAACTCTGTCATGGTTCTCCTCATCTACCTGGACACCCAGCTCCACACCCCCATGTAC TTCCTCCTCAGCCAACTGTCCCTCATGGACCTCATGCTCATCTGCACCACCGTACCCAAG ATGGCCTTCAACTACCTGTCTGGCAGCAAGTCCATTTCTATGGCTGGTTGTGTCACACAA ATTTTCTTCTATATATCACTGTCTGGCTCTGAATGTTTTCTTTTGGCTGTTATGGCTTAT GACCGCTATATTGCTATTTGCCACCCTCTAAGATATACCAATCTCATGAATCCTAAAATT TGTGGACTTATGGCTACCTTCTCCTGGATCCTGGGCTCTACAGATGGAATCATTGATGCT GTAGCCACATTTTCCTTCTCCTTTTGTGGGTCTCGGGAAATAGCCCACTTCTTCTGTGAA TTCCCTTCCCTACTAATCCTCTCATGCAATGACACATCAATATTTGAAGAGGTTATTTTC ATCTGCTGTATAGTAATGCTTGTTTTCCCTGTTGCAATCATCATTGCTTCCTATGCTCGA GTTATTCTGGCTGTCATTCACATGGGATCTGGAGAGGGTCGTTGCAAAGCTTTCACGACC TGTTCCTCTCACCTCATGGTGGTGGGAATGTACTATGGAGCAGCTTTGTTCATGTACATA CGGCCCACATCTGATCACTCCCCAACGCAGGACAAGATGGTGTCTGTATTCTACACCATC CTCACTCCCATGCTGAATCCCCTCATCTACAGCCTCCGCAACAAGGAGGTGACTAGAGCA TTCATGAAGATCTTAGGAAAGGGCAAGTCTGAGAGTGAGTTACCTCATAAACTTTATGTT TTGCTGTTTGCTAAATTCTTCTTTCTAATATCCATCTTTTTCTATGATGTCAAAATACTA GCATTGATTATGTACATTGCC |
| Conceptual translation |
MAWENQTFNSDFILLGIFNHSPPHTFLFFLVLGIFLVAFMGNSVMVLLIYLDTQLHTPMY FLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCVTQIFFYISLSGSECFLLAVMAY DRYIAICHPLRYTNLMNPKICGLMATFSWILGSTDGIIDAVATFSFSFCGSREIAHFFCE FPSLLILSCNDTSIFEEVIFICCIVMLVFPVAIIIASYARVILAVIHMGSGEGRCKAFTT CSSHLMVVGMYYGAALFMYIRPTSDHSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRA FMKILGKGKSESELPHKLYVLLFAKFFFLISIFFYDVKILALIMYIA Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 248,340,182 | 248,340,182 | large insertion | 22252bp insertion | rs72482064 (DbSNP) | |
| 1 | 248,343,350 | 248,343,349 | Ins(1) | -/C | rs34678055 (DbSNP) | |
| 1 | 248,343,543 | 248,343,543 | SYN | C/T | L/L | rs9435919 (DbSNP) |
| 1 | 248,343,547 | 248,343,547 | NS | C/G | S/C | rs61156873 (DbSNP) |
| 1 | 248,343,945 | 248,343,945 | NS | C/G | R/G | rs4244171 (DbSNP) |
| 1 | 248,343,990 | 248,343,990 | NS | C/T | R/C | rs4916104 (DbSNP) |
| 1 | 248,343,996 | 248,343,996 | NS | A/G | T/A | rs9435890 (DbSNP) |
| 1 | 248,344,156 | 248,344,156 | NS | A/G | Y/C | rs41311591 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 247,753,207 | 248,376,070 | CopyNumber | Variation_8353 (DGV) |
| 1 | 248,060,959 | 249,167,690 | CopyNumber | Variation_8354 (DGV) |
| 1 | 248,242,528 | 248,817,382 | CopyNumber | Variation_8935 (DGV) |
| 1 | 248,319,780 | 248,490,372 | CopyNumber | Variation_31702 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| R220G | C235R | C235Y | A237T | R293C | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | G | R | C | A | R | 49.77 | 0.103 |
| 2 | R | C | C | A | R | 45.78 | 0.103 |
| 3 | G | C | C | A | R | 2.23 | 0.103 |
| 4 | R | R | C | A | R | 1.38 | 0.103 |
| 5 | G | R | Y | A | R | 0.54 | 0.103 |
| 6 | G | R | C | T | R | 0.23 | 0.248 |
| 7 | G | R | C | A | C | 0.08 | 0.103 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2M2.aApr07-unspliced | main_exon | CDS | chr1 | 248,179,986 | 248,181,026 | + |
| 3UTR | chr1 | 248,181,026 | 248,181,029 | + | ||