OR2M7 Olfactory Receptor
| Gene Symbol | OR2M71 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | M |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | OR1-58, HsOR1.5.35 |
| External Ids | HGNC: 19594 GeneBank: AB065954, BK004486, NM_001004691 |
| Build #39 labels | OR2M7 |
| Chromosomal location | 1:248,323,633-248,324,568 (-) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2M2 | 92.26% | 310 |
| OR2M3 | 91.67% | 312 |
| OR2M5 | 92.63% | 312 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2M9 | 77% | 312 |
| Mouse | Or2m12 | 72% | 309 |
| Rat | Or2m12 | 72% | 307 |
| Cow | OR2M10 | 74% | 312 |
| Orang | OR2M3P | 91% | 307 |
| Orang | OR2M5P | 90% | 309 |
| Horse | OR2M24 | 76% | 312 |
| Chimp | OR2M2 | 92% | 312 |
| Chimp | OR2M3 | 92% | 312 |
| Chimp | OR2M5 | 92% | 312 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136946 |
| GNF Atlas2 | gnf1h10907_x_at |
| GNF Atlas2 | gnf1h10908_at |
Sequence information
| Nucleotide sequence |
ATGGCATGGGAGAATCAGACCTTCAACTCTGACTTCCTCCTCCTGGGAATCTTCAATCAT AGCCCCACCCACACCTTCCTCTTCTTTCTGGTCCTGGCCATCTTTTCAGTGGCCTTCATG GGAAACTCCATCATGGTTCTCCTCATCTACCTGGATACCCAGCTCCACACCCCCATGTAC TTCCTCCTCAGCCAACTGTCCCTCATGGACCTCATGCTCATCTGCACCACTGTACCCAAG ATGGCCTTCAACTACTTGTCTGGCAGCAAGTCCATTTCTATGGCTGGCTGTGCCACACAA ATTTTCTTCTATATATCATTGCTTGGCTCCGAATGCTTTCTGTTGGCTGTTATGTCTTAT GACCGCTACACTGCCATTTGCCACCCTCTAAGATACACCAATCTCATGAGACCCAAAATT TGTGGACTTATGACTGCCTTCTCCTGGATCCTGGGCTCTACAGATGGAATCATTGATGCT GTAGCGACATTTTCCTTCTCCTACTGTGGGTCTCGGGAAATAGCCCACTTCTGCTGTGAC TTCCCTTCCCTACTAATCCTCTCATGCAATGACACATCAATATTTGAAGAGGTTATTTTC ATCTGCTGTATAGTAATGCTTGTTTTCCCTGTTGCAATCATCATCACTTCCTATGCTCGA GTTATTCTGGCTGTCATTCACATGGGATCTGGAGAGGGACGTCGCAAAGCTTTTACTACT TGTTCCTCTCACCTCATGGTGGTGGGAATGTACTATGGAGCAGGTTTGTTCATGTGCATT CAGCCCACATCTCATCATTCTCCTATGCAGGACAAGATGGTGTCTGTATTCTACACCATC GTCACTCCCATGCTGAATCCTCTCATTTATAGCCTCCGCAACAAGGAAGTGACCAGAGCA TTAATGAAAATCTTAGGAAAGGGCAAGTCTGGAGAT |
| Conceptual translation |
MAWENQTFNSDFLLLGIFNHSPTHTFLFFLVLAIFSVAFMGNSIMVLLIYLDTQLHTPMY FLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYISLLGSECFLLAVMSY DRYTAICHPLRYTNLMRPKICGLMTAFSWILGSTDGIIDAVATFSFSYCGSREIAHFCCD FPSLLILSCNDTSIFEEVIFICCIVMLVFPVAIIITSYARVILAVIHMGSGEGRRKAFTT CSSHLMVVGMYYGAGLFMCIQPTSHHSPMQDKMVSVFYTIVTPMLNPLIYSLRNKEVTRA LMKILGKGKSGD Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | G/C | D/E | 1000GP (YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | G/A | I/I | 1000GP (YRI) |
| 1 | 248,323,714 | 248,323,714 | SYN | C/T | L/L | 1000GP (CEU, CHBJPT) |
| 1 | 248,323,932 | 248,323,932 | NS | T/C | I/V | 1000GP (CEU) |
| 1 | 248,324,336 | 248,324,336 | NS | A/G | V/A | 1000GP (CEU, CHBJPT) |
| 1 | 248,465,273 | 248,465,273 | large insertion | 25914bp insertion | rs72482062 (DbSNP) | |
| 1 | 248,486,955 | 248,486,955 | NS | C/T | G/R | rs11589743 (DbSNP) |
| 1 | 248,487,016 | 248,487,016 | SYN | C/T | L/L | rs4451579 (DbSNP) |
| 1 | 248,487,031 | 248,487,031 | SYN | G/A | I/I | rs62000404 (DbSNP) |
| 1 | 248,487,044 | 248,487,044 | NS | G/A | A/V | rs62000401 (DbSNP) |
| 1 | 248,487,168 | 248,487,168 | NS | A/G | C/R | rs55956377 (DbSNP) |
| 1 | 248,487,186 | 248,487,186 | NS | C/G | G/R | rs74153159 (DbSNP) |
| 1 | 248,487,300 | 248,487,300 | NS | C/T | D/N | rs4916129 (DbSNP) |
| 1 | 248,487,338 | 248,487,338 | NS | A/C | F/C | rs4916130 (DbSNP) |
| 1 | 248,487,560 | 248,487,560 | NS | C/T | C/Y | rs41304034 (DbSNP) |
| 1 | 248,487,638 | 248,487,638 | NS | A/G | V/A | rs7555310 (DbSNP) |
| 1 | 248,487,701 | 248,487,701 | NS | A/G | I/T | rs41304036 (DbSNP) |
| 1 | 248,487,764 | 248,487,764 | NS | G/A | S/L | rs61999307 (DbSNP) |
| 1 | 248,487,768 | 248,487,768 | NS | A/G | F/L | rs7555424 (DbSNP) |
| 1 | 248,487,834 | 248,487,834 | NS | T/G | I/L | rs62000388 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 248,060,959 | 249,167,690 | CopyNumber | Variation_8354 (DGV) |
| 1 | 248,242,528 | 248,817,382 | CopyNumber | Variation_8935 (DGV) |
| 1 | 248,319,780 | 248,490,372 | CopyNumber | Variation_31702 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| D271E | R235C | G229R | V211F | D191N | C169Y | L143R | V78A | T57I | S36L | F35L | L13I | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | D | R | G | V | N | C | L | A | T | S | L | L | 36.87 | 0.285 |
| 2 | D | R | G | V | D | C | L | A | T | S | L | L | 33.33 | 0.285 |
| 3 | D | R | G | V | D | C | L | V | T | S | F | L | 22.12 | 0.103 |
| 4 | D | R | G | V | D | C | L | V | T | L | F | I | 2.61 | 0.103 |
| 5 | E | R | G | V | D | C | L | A | T | S | L | L | 1.46 | 0.285 |
| 6 | D | R | G | V | D | C | L | A | T | S | F | L | 0.69 | 0.103 |
| 7 | D | R | R | V | N | C | L | A | T | S | L | L | 0.61 | 0.285 |
| 8 | D | R | G | V | D | Y | L | A | T | S | L | L | 0.38 | 0.285 |
| 9 | D | R | G | V | N | C | L | V | T | S | L | L | 0.38 | 0.285 |
| 10 | D | R | G | V | D | C | L | V | T | S | L | I | 0.31 | 0.285 |
| 11 | D | R | G | F | D | C | L | A | T | S | L | L | 0.23 | 0.285 |
| 12 | D | R | G | V | D | C | L | V | T | S | L | L | 0.23 | 0.285 |
| 13 | D | R | G | V | N | C | R | A | T | S | L | L | 0.15 | 0.285 |
| 14 | D | R | G | V | D | C | L | A | I | S | L | L | 0.15 | 0.285 |
| 15 | D | R | G | V | D | C | R | A | T | S | L | L | 0.15 | 0.285 |
| 16 | D | R | G | V | N | C | L | A | I | S | L | L | 0.08 | 0.285 |
| 17 | D | C | G | V | D | C | L | V | T | S | F | L | 0.08 | 0.103 |
| 18 | D | R | G | V | N | C | L | V | T | S | F | L | 0.08 | 0.103 |
| 19 | D | R | G | V | D | Y | L | V | T | S | F | L | 0.08 | 0.103 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2M7.aApr07-unspliced | main_exon | 3UTR | chr1 | 248,323,630 | 248,323,633 | - |
| CDS | chr1 | 248,323,633 | 248,324,568 | - | ||