OR2M3 Olfactory Receptor
| Gene Symbol | OR2M31 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | M |
| Pseudogene | No |
| CORP pseudogene probability score | 0.04 (functional) |
| Aliases | OR1-54, OST003, HsOR1.5.31 |
| External Ids | HGNC: 8269 GeneBank: AB065952, AF399483, BK004482, NM_001004689 |
| Build #39 labels | OR2M6, OR2M3P |
| Chromosomal location | 1:248,203,068-248,204,003 (+) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2M2 | 92.26% | 310 |
| OR2M5 | 92.95% | 312 |
| OR2M7 | 91.67% | 312 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2M9 | 79% | 312 |
| Mouse | Or2m12 | 75% | 308 |
| Rat | Or2m12 | 76% | 306 |
| Cow | OR2M10 | 78% | 312 |
| Orang | OR2M5P | 92% | 312 |
| Orang | OR2M3P | 92% | 307 |
| Horse | OR2M24 | 79% | 312 |
| Chimp | OR2M7 | 92% | 312 |
| Chimp | OR2M2 | 92% | 312 |
| Chimp | OR2M5 | 92% | 312 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136971 |
| GNF Atlas2 | gnf1h02158_s_at |
| GNF Atlas2 | gnf1h02159_x_at |
Sequence information
| Nucleotide sequence |
ATGGCAAGGGAGAATTCGACCTTCAACTCCGACTTCATCCTCCTGGGAATCTTCAATCAC AGCCCCACCCACACCTTCCTCTTCTTTCTGGTCCTGGCCATCTTTTCAGTGGCCTTCATG GGAAACTCTGTCATGGTTCTCCTCATCTACCTGGACACCCAGCTCCACACCCCCATGTAC CTCCTCCTCAGCCAACTGTCCCTCATGGACCTCATGCTCATCTGCACCACCGTACCCAAG ATGGCCTTCAACTACCTGTCTGGCAGCAAGTCCATTTCTATGGCTGGTTGTGCCACACAA ATTTTCTTCTATACATCACTGCTTGGCTCTGAGTGCTTTCTTTTGGCTGTTATGGCTTAT GACCGCTACACTGCCATTTGCCACCCTCTAAGATACACCAATCTCATGAGCCCTAAAATT TGTGGACTTATGACTGCCTTTTCCTGGATCCTGGGCTCTACGGATGGAATTATTGATGTT GTAGCAACATTTTCCTTCTCCTACTGTGGGTCTCGGGAAATAGCCCACTTCTTCTGTGAC TTCCCCTCCCTACTAATCCTCTCATGCAGTGACACATCAATATTTGAAAAGATTCTTTTC ATCTGCTGTATAGTAATGATTGTTTTCCCTGTTGCAATCATCATTGCTTCCTATGCTCGA GTTATCCTGGCTGTCATTCACATGGGATCTGGAGAGGGTCGTCGCAAAGCTTTTACTACT TGTTCCTCTCACCTCTTGGTGGTGGGAATGTACTATGGAGCAGCTTTGTTCATGTACATA CGGCCCACATCTGATCGCTCCCCAACACAGGACAAGATGGTGTCTGTATTCTACACCATC CTCACTCCCATGTTGAATCCCCTCATCTACAGCCTCCGCAACAAGGAGGTGACCAGAGCA TTCATGAAGATCTTAGGAAAGGGCAAGTCTGGAGAG |
| Conceptual translation |
MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMY LLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAY DRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCD FPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTT CSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRA FMKILGKGKSGE Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | G/A | D/N | 1000GP (YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | G/A | E/E | 1000GP (YRI, YRI, YRI) |
| 1 | 248,203,400 | 248,203,400 | SYN | G/A | E/E | 1000GP (CEU, CHBJPT) |
| 1 | 248,203,490 | 248,203,490 | SYN | T/C | C/C | 1000GP (CEU, CHBJPT) |
| 1 | 248,366,493 | 248,366,493 | NS | A/T | N/Y | rs12562699 (DbSNP) |
| 1 | 248,366,702 | 248,366,702 | SYN | A/G | E/E | rs4916112 (DbSNP) |
| 1 | 248,366,765 | 248,366,765 | SYN | C/T | Y/Y | rs61736249 (DbSNP) |
| 1 | 248,366,792 | 248,366,792 | SYN | C/T | C/C | rs12562957 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 247,753,207 | 248,376,070 | CopyNumber | Variation_8353 (DGV) |
| 1 | 248,060,959 | 249,167,690 | CopyNumber | Variation_8354 (DGV) |
| 1 | 248,242,528 | 248,817,382 | CopyNumber | Variation_8935 (DGV) |
| 1 | 248,319,780 | 248,490,372 | CopyNumber | Variation_31702 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| D11N | A216T | Y259H | I289N | R293S | M302T | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | D | A | Y | I | R | M | 97.93 | 0.103 |
| 2 | D | A | Y | N | R | M | 0.77 | 0.103 |
| 3 | D | T | Y | I | R | M | 0.38 | 0.103 |
| 4 | D | A | H | I | R | M | 0.31 | 0.103 |
| 5 | N | A | Y | I | R | M | 0.23 | 0.103 |
| 6 | D | A | Y | I | S | M | 0.23 | 0.103 |
| 7 | D | A | Y | I | R | T | 0.15 | 0.103 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2M3.aApr07-unspliced | main_exon | CDS | chr1 | 248,203,068 | 248,204,003 | + |
| 3UTR | chr1 | 248,204,003 | 248,204,006 | + | ||