OR2T27 Olfactory Receptor
| Gene Symbol | OR2T271 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | T |
| Pseudogene | No |
| CORP pseudogene probability score | 0.04 (functional) |
| Aliases | OR1-67, HsOR1.5.49 |
| External Ids | HGNC: 31252 GeneBank: AB065611, BK004474, NM_001001824 |
| Build #39 labels | |
| Chromosomal location | 1:248,649,934-248,650,884 (-) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2T7 | 98.62% | 290 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2T1 | 70% | 314 |
| Mouse | Or2t1 | 69% | 315 |
| Rat | Or2t1 | 69% | 313 |
| Cow | OR2T1 | 69% | 315 |
| Orang | OR2T27FP | 91% | 313 |
| Horse | OR2T27P | 88% | 317 |
| Horse | OR2T27HP | 87% | 317 |
| Chimp | OR2T27BP | 96% | 313 |
Sequence information
| Nucleotide sequence |
ATGGAGCAGAGCAATTATTCCGTGTATGCCGACTTTATCCTTCTGGGTTTGTTCAGCAAC GCCCGTTTCCCCTGGCTTCTCTTTGCCCTCATTCTCCTGGTCTTTTTGACCTCCATAGCC AGCAACGTGGTCAAGATCATTCTCATCCACATAGACTCCCGCCTCCACACCCCCATGTAC TTCCTGCTCAGCCAGCTCTCCCTCAGGGACATCCTGTATATTTCCACCATTGTGCCCAAA ATGCTGGTCGACCAGGTGATGAGCCAGAGAGCCATTTCCTTTGCTGGATGCACTGCCCAA CACTTCCTCTACTTGACCTTAGCAGGGGCTGAGTTCTTCCTCCTAGGACTCATGTCCTAT GATCGCTACGTAGCCATCTGCAACCCTCTGCACTATCCTGTCCTCATGAGCCGCAAGATC TGCTGGTTGATTGTGGCGGCAGCCTGGCTGGGAGGGTCTATCGATGGTTTCTTGCTCACC CCCGTCACCATGCAGTTCCCCTTCTGTGCCTCTCGGGAGATCAACCACTTCTTCTGCGAG GTGCCTGCCCTTCTGAAGCTCTCCTGCACGGACACATCAGCCTACGAGACAGCCATGTAT GTCTGCTGTATTATGATGCTCCTCATCCCTTTCTCTGTCATCTCGGGCTCTTACACAAGA ATTCTCATTACTGTTTATAGGATGAGCGAGGCAGAGGGGAGGGGAAAGGCTGTGGCCACC TGCTCCTCACACATGGTGGTTGTCAGCCTCTTCTATGGGGCTGCCATGTACACATACGTG CTGCCTCATTCTTACCACACCCCTGAGCAGGACAAAGCTGTATCTGCCTTCTACACCATC CTTACTCCCATGCTCAATCCACTCATTTACAGCCTTAGGAACAAGGATGTCACAGGGGCC CTACAGAAGGTTGTGGGGAGGTGTGTGTCCTCAGGAAAGGTAACCACTTTC |
| Conceptual translation |
MEQSNYSVYADFILLGLFSNARFPWLLFALILLVFLTSIASNVVKIILIHIDSRLHTPMY FLLSQLSLRDILYISTIVPKMLVDQVMSQRAISFAGCTAQHFLYLTLAGAEFFLLGLMSY DRYVAICNPLHYPVLMSRKICWLIVAAAWLGGSIDGFLLTPVTMQFPFCASREINHFFCE VPALLKLSCTDTSAYETAMYVCCIMMLLIPFSVISGSYTRILITVYRMSEAEGRGKAVAT CSSHMVVVSLFYGAAMYTYVLPHSYHTPEQDKAVSAFYTILTPMLNPLIYSLRNKDVTGA LQKVVGRCVSSGKVTTF Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | A/C | L/V | 1000GP (YRI) |
| 1 | 100 | -100 | SYN | A/G | L/L | 1000GP (YRI, YRI) |
| 1 | 248,649,970 | 248,649,970 | SYN | C/A | V/V | 1000GP (CEU) |
| 1 | 248,649,979 | 248,649,979 | SYN | C/T | Q/Q | 1000GP (CEU, CHBJPT) |
| 1 | 248,650,526 | 248,650,526 | NS | T/C | Y/C | 1000GP (CEU) |
| 1 | 248,650,779 | 248,650,779 | NS | A/C | L/V | 1000GP (CEU, CHBJPT) |
| 1 | 248,813,271 | 248,813,271 | SYN | C/A | V/V | rs2802081 (DbSNP) |
| 1 | 248,813,280 | 248,813,280 | SYN | C/T | Q/Q | rs72769026 (DbSNP) |
| 1 | 248,813,292 | 248,813,292 | SYN | C/T | T/T | rs71199329 (DbSNP) |
| 1 | 248,813,343 | 248,813,343 | SYN | A/G | L/L | rs1938148 (DbSNP) |
| 1 | 248,813,827 | 248,813,827 | NS | C/T | C/Y | rs1782241 (DbSNP) |
| 1 | 248,813,901 | 248,813,901 | SYN | A/T | A/A | rs71523294 (DbSNP) |
| 1 | 248,814,052 | 248,814,052 | NS | A/T | M/K | rs28533004 (DbSNP) |
| 1 | 248,814,080 | 248,814,080 | NS | A/C | L/V | rs1782242 (DbSNP) |
| 1 | 248,814,126 | 248,814,126 | SYN | A/G | N/N | rs28418327 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 248,060,959 | 249,167,690 | CopyNumber | Variation_8354 (DGV) |
| 1 | 248,242,528 | 248,817,382 | CopyNumber | Variation_8935 (DGV) |
| 1 | 248,500,109 | 248,865,374 | CopyNumber | Variation_3340 (DGV) |
| 1 | 248,522,680 | 249,158,239 | CopyNumber | Variation_8355 (DGV) |
| 1 | 248,595,681 | 248,817,382 | CopyNumber | Variation_2359 (DGV) |
| 1 | 248,626,918 | 248,830,541 | Inversion | Variation_37092 (DGV) |
| 1 | 248,687,510 | 248,865,377 | CopyNumber | Variation_0017 (DGV) |
| 1 | 248,701,948 | 248,877,423 | CopyNumber | Variation_2056 (DGV) |
| 1 | 248,811,235 | 248,814,285 | Deletion, CopyNumber | #306 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| Y226H | Y218H | V134D | Y120C | L36V | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | Y | Y | V | Y | V | 64.21 | 0.094 |
| 2 | Y | Y | V | C | V | 20.58 | 0.094 |
| 3 | Y | Y | D | C | V | 6.45 | 0.094 |
| 4 | Y | Y | V | Y | L | 3.15 | 0.094 |
| 5 | Y | Y | D | Y | V | 1.84 | 0.094 |
| 6 | H | Y | V | Y | V | 1.15 | 0.094 |
| 7 | Y | H | V | Y | V | 1.00 | 1.000 |
| 8 | H | Y | V | Y | L | 0.92 | 0.094 |
| 9 | Y | Y | D | Y | L | 0.23 | 0.094 |
| 10 | Y | H | V | C | V | 0.15 | 1.000 |
| 11 | Y | Y | V | C | L | 0.08 | 0.094 |
| 12 | Y | Y | D | C | L | 0.08 | 0.094 |
| 13 | Y | H | V | C | L | 0.08 | 1.000 |
| 14 | Y | H | D | Y | V | 0.08 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2T27.aApr07-unspliced | main_exon | 3UTR | chr1 | 248,649,931 | 248,649,934 | - |
| CDS | chr1 | 248,649,934 | 248,650,884 | - | ||