OR4K13 Olfactory Receptor
| Gene Symbol | OR4K131 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | K |
| Pseudogene | No |
| CORP pseudogene probability score | 0.08 (functional) |
| Aliases | OR14-27, HsOR14.1.18, ORL3689 |
| External Ids | HGNC: 15351 GeneBank: AB065559, BK004449, NM_001004714 ORDB: ORL3689 |
| Build #39 labels | OR4K13 |
| Chromosomal location | 14:20,033,847-20,034,758 (-) |
| Cluster | 14@20b |
| Synteny | CLIC#32 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4K14 | 67.77% | 301 |
| OR4K15 | 68% | 300 |
| OR4K3P | 64.33% | 300 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4K13BP | 91% | 300 |
| Mouse | Or4k15 | 67% | 300 |
| Rat | Or4k15 | 67% | 300 |
| Cow | OR4L17 | 69% | 296 |
| Orang | OR4K15 | 68% | 300 |
| Horse | OR4K65 | 70% | 300 |
| Chimp | OR4K15 | 69% | 300 |
Sequence information
| Nucleotide sequence |
ATGGAAAGAGCAAACCATTCAGTGGTATCGGAATTTATTTTGTTGGGACTTTCCAAATCT CAAAATCTTCAGATTTTATTCTTCTTGGGATTCTCTGTGGTCTTCGTGGGGATTGTGTTA GGAAACCTGCTCATCTTGGTGACTGTGACCTTTGATTCGCTCCTTCACACACCAATGTAT TTTCTGCTTAGCAACCTCTCCTGCATTGATATGATCCTGGCTTCTTTTGCTACCCCTAAG ATGATTGTAGATTTCCTCCGAGAACGTAAGACCATCTCATGGTGGGGATGTTATTCCCAG ATGTTCTTTATGCACCTCCTGGGTGGGAGTGAGATGATGTTGCTTGTAGCCATGGCAATA GACAGGTATGTTGCCATATGCAAACCCCTCCATTACATGACCATCATGAGCCCACGGGTG CTCACTGGGCTACTGTTATCCTCCTATGCAGTTGGATTTGTGCACTCATCTAGTCAAATG GCTTTCATGTTGACTTTGCCCTTCTGTGGTCCCAATGTTATAGACAGCTTTTTCTGTGAC CTTCCCCTTGTGATTAAACTTGCCTGCAAGGACACCTACATCCTACAGCTCCTGGTCATT GCTGACAGTGGGCTCCTGTCACTGGTCTGCTTCCTCCTCTTGCTTGTCTCCTATGGAGTC ATAATATTCTCAGTTAGGTACCGTGCTGCTAGTCGATCCTCTAAGGCTTTCTCCACTCTC TCAGCTCACATCACAGTTGTGACTCTGTTCTTTGCTCCGTGTGTCTTTATCTACGTCTGG CCCTTCAGCAGATACTCGGTAGATAAAATTCTTTCTGTGTTTTACACAATTTTCACACCT CTCTTAAATCCTATTATTTATACATTAAGAAATCAAGAGGTAAAAGCAGCCATTAAAAAA AGACTCTGCATA |
| Conceptual translation |
MERANHSVVSEFILLGLSKSQNLQILFFLGFSVVFVGIVLGNLLILVTVTFDSLLHTPMY FLLSNLSCIDMILASFATPKMIVDFLRERKTISWWGCYSQMFFMHLLGGSEMMLLVAMAI DRYVAICKPLHYMTIMSPRVLTGLLLSSYAVGFVHSSSQMAFMLTLPFCGPNVIDSFFCD LPLVIKLACKDTYILQLLVIADSGLLSLVCFLLLLVSYGVIIFSVRYRAASRSSKAFSTL SAHITVVTLFFAPCVFIYVWPFSRYSVDKILSVFYTIFTPLLNPIIYTLRNQEVKAAIKK RLCI Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 14 | 20,502,044 | 20,502,044 | NS | G/T | Q/K | rs17277025 (DbSNP) |
| 14 | 20,502,120 | 20,502,120 | SYN | C/T | S/S | rs17277032 (DbSNP) |
| 14 | 20,033,885 | 20,033,885 | NS | G/T | Q/K | 1000GP (CEU, CHBJPT) |
| 14 | 20,033,961 | 20,033,961 | SYN | C/T | S/S | 1000GP (CEU, CHBJPT) |
| 14 | 20,034,443 | 20,034,443 | NS | G/A | L/F | 1000GP (CHBJPT) |
| 14 | 100 | -100 | NS | G/T | Q/K | 1000GP (YRI, YRI) |
| 14 | 100 | -100 | SYN | C/T | P/P | 1000GP (YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 14 | 20,371,142 | 20,505,020 | CopyNumber | Variation_2175 (DGV) |
| 14 | 20,203,125 | 20,539,108 | CopyNumber | Variation_3036 (DGV) |
| 14 | 19,662,531 | 20,556,187 | CopyNumber | Variation_3929 (DGV) |
| 14 | 20,362,952 | 20,525,999 | CopyNumber | Variation_4827 (DGV) |
| 14 | 20,203,125 | 20,626,160 | CopyNumber | Variation_8763 (DGV) |
| 14 | 20,203,125 | 20,716,841 | CopyNumber | Variation_8765 (DGV) |
| 14 | 20,239,479 | 20,511,107 | CopyNumber | Variation_9235 (DGV) |
| 14 | 20,203,125 | 20,525,833 | CopyNumber | Variation_34547 (DGV) |
| 14 | 20,203,125 | 20,655,466 | CopyNumber | Variation_34656 (DGV) |
| 14 | 20,203,125 | 20,550,348 | CopyNumber | Variation_34660 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| Q292K | P253L | P138A | L106F | F102I | V47M | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | Q | P | P | L | F | V | 91.01 | 0.219 |
| 2 | K | P | P | L | F | V | 5.91 | 0.219 |
| 3 | Q | P | P | L | F | M | 1.23 | 0.219 |
| 4 | Q | P | P | F | F | V | 0.92 | 0.219 |
| 5 | Q | P | A | L | F | V | 0.61 | 0.219 |
| 6 | Q | P | P | L | I | V | 0.23 | 0.219 |
| 7 | Q | L | P | L | F | V | 0.08 | 0.302 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR4K13.aApr07-unspliced | main_exon | 3UTR | chr14 | 20,033,844 | 20,033,847 | - |
| CDS | chr14 | 20,033,847 | 20,034,758 | - | ||