OR56A4 Olfactory Receptor
| Gene Symbol | OR56A41 (View this gene in GeneCards) |
| Family | 56 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.49 (functional) |
| Aliases | OR11-49, HsOR11.3.93, ORL3320 |
| External Ids | HGNC: 14791 GeneBank: AB065818, BK004255, NM_001005179 ORDB: ORL3320 |
| Build #39 labels | OR56A4 |
| Chromosomal location | 11:6,002,054-6,002,992 (-) |
| Cluster | 11@6 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR56A1 | 83.33% | 312 |
| OR56A5 | 87.22% | 313 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR56A4B | 89% | 313 |
| Dog | OR56A4C | 89% | 313 |
| Mouse | Or56a4 | 87% | 309 |
| Rat | Or56a5 | 84% | 312 |
| Cow | OR56A4E | 89% | 313 |
| Cow | OR56A4P | 89% | 313 |
| Cow | OR56A4D | 88% | 313 |
| Orang | OR56A1 | 83% | 312 |
| Horse | OR56A1 | 81% | 312 |
| Chimp | OR56A5 | 88% | 313 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136986 |
Sequence information
| Nucleotide sequence |
ATGGCATCTCCCAGCAATGACTCCACTGCCCCAGTCTCTGAATTCCTCCTCATCTGCTTC CCCAACTTCCAGAGCTGGCAGCACTGGTTGTCTCTGCCCCTCAGCCTTCTCTTCCTCCTG GCCATGGGAGCTAACACCACCCTCCTGATCACCATCCAGCTGGAGGCCTCTCTGCACCAG CCCCTGTACTACCTGCTCAGCCTCCTCTCCCTGCTGGACATCGTGCTCTGCCTCACCGTC ATCCCCAAGGTCCTGGCCATCTTCTGGTTTGACCTCAGGTCGATCAGCTTCCCAGCCTGC TTCCTCCAGATGTTCATCATGAACAGTTTTTTGACCATGGAGTCCTGCACGTTCATGGTC ATGGCCTATGACCGTTATGTGGCCATCTGCCATCCATTGAGATACCCGTCTATCATCACT GACCAGTTTGTGGCTAGGGCCGTGGTCTTTGTTATAGCCCGGAATGCCTTTGTTTCTCTT CCTGTTCCCATGCTTTCTGCCAGGCTCAGATACTGTGCAGGAAACATAATCAAGAACTGC ATCTGCAGTAACCTGTCTGTGTCCAAACTCTCTTGTGATGACATCACTTTCAATCAGCTC TACCAGTTTGTGGCAGGCTGGACTCTGTTGGGCTCTGATCTTATCCTTATTGTTATCTCC TATTCTTTTATATTGAAAGTTGTGCTTAGGATCAAGGCCGAGGGTGCTGTGGCCAAGGCC TTGAGCACGTGTGGTTCCCACTTCATCCTCATCCTCTTCTTCAGCACAGTCCTGCTGGTT CTGGTCATCACTAACCTGGCCAGGAAGAGAATTCCTCCAGATGTCCCCATCCTGCTCAAC ATCCTGCACCACCTCATTCCCCCAGCTCTGAACCCCATTGTTTATGGTGTGAGAACCAAG GAGATCAAGCAGGGAATCCAAAACCTGCTGAAGAGGTTG |
| Conceptual translation |
MASPSNDSTAPVSEFLLICFPNFQSWQHWLSLPLSLLFLLAMGANTTLLITIQLEASLHQ PLYYLLSLLSLLDIVLCLTVIPKVLAIFWFDLRSISFPACFLQMFIMNSFLTMESCTFMV MAYDRYVAICHPLRYPSIITDQFVARAVVFVIARNAFVSLPVPMLSARLRYCAGNIIKNC ICSNLSVSKLSCDDITFNQLYQFVAGWTLLGSDLILIVISYSFILKVVLRIKAEGAVAKA LSTCGSHFILILFFSTVLLVLVITNLARKRIPPDVPILLNILHHLIPPALNPIVYGVRTK EIKQGIQNLLKRL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 6,023,762 | 6,023,762 | NS | C/T | R/Q | rs17809527 (DbSNP) |
| 11 | 6,023,640 | 6,023,640 | NS | C/T | V/I | rs11040249 (DbSNP) |
| 11 | 6,023,581 | 6,023,581 | SYN | A/G | L/L | rs11040248 (DbSNP) |
| 11 | 6,023,818 | 6,023,818 | SYN | A/G | Y/Y | rs10839221 (DbSNP) |
| 11 | 6,002,351 | 6,002,351 | SYN | A/G | L/L | 1000GP (CEU, CHBJPT) |
| 11 | 6,002,410 | 6,002,410 | NS | T/C | I/V | 1000GP (CEU, CHBJPT) |
| 11 | 6,002,588 | 6,002,588 | SYN | G/A | Y/Y | 1000GP (CEU, CHBJPT) |
| 11 | 100 | -100 | SYN | A/G | L/L | 1000GP (YRI, YRI, YRI) |
| 11 | 100 | -100 | NS | T/C | I/V | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 5,505,764 | 6,194,475 | CopyNumber | Variation_34458 (DGV) |
| 11 | 6,021,284 | 6,024,322 | CopyNumber | #64 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| I247V | R206Q | % Freq | CORP | |
|---|---|---|---|---|
| 1 | I | R | 83.33 | 0.939 |
| 2 | V | R | 16.44 | 0.939 |
| 3 | V | Q | 0.23 | 0.939 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR56A4.aApr07-unspliced | main_exon | 3UTR | chr11 | 6,002,051 | 6,002,054 | - |
| CDS | chr11 | 6,002,054 | 6,002,992 | - | ||
| 5UTR | chr11 | 6,002,992 | 6,003,148 | - | ||