OR5AP2 Olfactory Receptor
| Gene Symbol | OR5AP21 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | AP |
| Pseudogene | No |
| CORP pseudogene probability score | 0.41 (functional) |
| Aliases | OR11-146, HsOR11.11.84, ORL3401 |
| External Ids | HGNC: 15258 GeneBank: AB065854, BK004594, NM_001002925 ORDB: ORL3401 |
| Build #39 labels | OR5AP2 |
| Chromosomal location | 11:56,641,492-56,642,442 (-) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5AP1P | 64.9% | 302 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5AP1 | 69% | 300 |
| Mouse | Or5ap2 | 86% | 317 |
| Rat | Or5ap2 | 84% | 317 |
| Rat | Or5ap2b | 81% | 317 |
| Cow | OR5AP2P | 82% | 313 |
| Orang | OR9S18 | 55% | 303 |
| Horse | OR5AP2C | 88% | 317 |
| Chimp | OR5W2 | 58% | 304 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | BX279705 |
| mRNA | BC136990 |
| GNF Atlas2 | gnf1h05766_at |
Sequence information
| Nucleotide sequence |
ATGATGAGACTTATGAAAGAGGTTCGAGGCAGAAATCAAACAGAAGTAACAGAATTTCTC CTCTTAGGACTTTCCGACAATCCAGATCTACAAGGAGTCCTCTTTGCATTGTTTCTGTTG ATCTATATGGCAAACATGGTGGGCAATTTGGGGATGATTGTATTGATTAAGATTGATCTC TGTCTCCACACCCCCATGTATTTCTTTCTCAGTAGCCTCTCTTTTGTAGATGCCTCTTAC TCTTCTTCCGTCACTCCCAAGATGCTGGTGAACCTCATGGCTGAGAATAAGGCCATTTCT TTTCATGGATGTGCTGCCCAGTTCTACTTCTTTGGCTCCTTCCTGGGGACTGAGTGCTTC CTGTTGGCCATGATGGCATATGACCGCTATGCAGCCATTTGGAACCCCCTGCTCTACCCA GTTCTCGTGTCTGGGAGAATTTGCTTTTTGCTAATAGCTACCTCCTTCTTAGCAGGTTGT GGAAATGCAGCCATACATACAGGGATGACTTTTAGGTTGTCCTTTTGTGGTTCTAATAGG ATCAACCATTTCTACTGTGACACCCCGCCACTGCTCAAACTCTCTTGCTCTGATACCCAC TTCAATGGCATTGTGATCATGGCATTCTCAAGTTTTATTGTCATCAGCTGTGTTATGATT GTCCTCATTTCCTACCTGTGTATCTTCATTGCCGTCTTGAAGATGCCTTCGTTAGAGGGC AGGCACAAAGCCTTCTCCACCTGTGCCTCTTACCTCATGGCTGTCACCATATTCTTTGGA ACAATCCTCTTCATGTACTTGCGCCCTACATCTAGCTACTCAATGGAGCAAGACAAGGTT GTCTCTGTCTTTTATACAGTAATAATCCCTGTGCTAAATCCCCTCATCTATAGTTTAAAA AATAAGGATGTAAAAAAGGCCCTAAAGAAGATCTTATGGAAACACATCTTG |
| Conceptual translation |
MMRLMKEVRGRNQTEVTEFLLLGLSDNPDLQGVLFALFLLIYMANMVGNLGMIVLIKIDL CLHTPMYFFLSSLSFVDASYSSSVTPKMLVNLMAENKAISFHGCAAQFYFFGSFLGTECF LLAMMAYDRYAAIWNPLLYPVLVSGRICFLLIATSFLAGCGNAAIHTGMTFRLSFCGSNR INHFYCDTPPLLKLSCSDTHFNGIVIMAFSSFIVISCVMIVLISYLCIFIAVLKMPSLEG RHKAFSTCASYLMAVTIFFGTILFMYLRPTSSYSMEQDKVVSVFYTVIIPVLNPLIYSLK NKDVKKALKKILWKHIL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 56,409,010 | 56,409,010 | NS | A/T | D/E | rs61747872 (DbSNP) |
| 11 | 56,409,603 | 56,409,603 | NS | C/T | A/T | rs11606499 (DbSNP) |
| 11 | 56,409,599 | 56,409,599 | NS | T/C | Q/R | rs61732328 (DbSNP) |
| 11 | 56,409,533 | 56,409,533 | NS | T/C | H/R | rs61743175 (DbSNP) |
| 11 | 56,409,039 | 56,409,039 | NS | T/G | T/P | rs61742762 (DbSNP) |
| 11 | 56,641,534 | 56,641,534 | NS | A/T | D/E | 1000GP (CEU) |
| 11 | 56,642,127 | 56,642,127 | NS | C/T | A/T | 1000GP (CEU) |
| 11 | 100 | -100 | NS | C/T | R/H | 1000GP (YRI, YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| D302E | R128H | Q106R | A105T | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | D | R | Q | A | 82.49 | 1.000 |
| 2 | D | R | Q | T | 13.44 | 1.000 |
| 3 | E | R | Q | A | 3.00 | 1.000 |
| 4 | D | R | R | A | 0.61 | 1.000 |
| 5 | D | H | Q | A | 0.46 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5AP2.aApr07-unspliced | main_exon | 3UTR | chr11 | 56,641,489 | 56,641,492 | - |
| CDS_partial | chr11 | 56,641,492 | 56,642,439 | - | ||