OR5C1 Olfactory Receptor
| Gene Symbol | OR5C11 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | C |
| Pseudogene | No |
| CORP pseudogene probability score | 0.22 (functional) |
| Aliases | hRPK-465_F_21, OR9-F, OR9-31, HsOR9.6.14, ORL3245 |
| External Ids | HGNC: 8331 GeneBank: AB065725, AF399514, BK004233, NM_001001923 ORDB: ORL3245 |
| Build #39 labels | OR5C2P, OR5C1 |
| Chromosomal location | 9:122,788,933-122,789,892 (+) |
| Cluster | 9@125 |
| Synteny | CLIC#21 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5AR1 | 57.68% | 293 |
| OR5W2 | 58.36% | 293 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5W2B | 59% | 293 |
| Mouse | Or5c1 | 85% | 320 |
| Rat | Or5c1 | 85% | 320 |
| Cow | OR5AR1 | 56% | 311 |
| Orang | OR5C1P | 82% | 306 |
| Horse | OR5W2 | 59% | 293 |
| Chimp | OR5W2 | 59% | 297 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | CV366136 |
| mRNA | BC136701 |
| GNF Atlas2 | gnf1h10870_at |
Sequence information
| Nucleotide sequence |
ATGAACTCAGAGAACCTCACCCGGGCCGCGGTTGCCCCTGCTGAATTCGTCCTCCTGGGC ATCACAAATCGCTGGGACCTGCGTGTGGCCCTCTTCCTGACCTGCCTGCCTGTCTACCTG GTGAGCCTGCTGGGAAACATGGGCATGGCGCTGCTGATCCGCATGGATGCCCGGCTCCAC ACACCTATGTACTTCTTCCTGGCCAACCTCTCCCTGCTGGATGCCTGCTATTCCTCCGCC ATCGGCCCCAAGATGCTAGTGGACCTGCTGCTGCCCCGAGCCACCATCCCTTACACAGCC TGTGCCCTCCAGATGTTTGTCTTTGCAGGTCTGGCTGATACTGAGTGTTGCTTGCTGGCA GCCATGGCCTATGACCGCTACGTGGCCATCAGAAACCCACTTCTCTATACAACAGCTATG TCGCAGCGTCTATGCCTGGCCTTGCTGGGAGCATCAGGCCTGGGTGGGGCAGTGAGTGCC TTTGTTCACACAACCCTCACCTTCCGCCTGAGCTTCTGCCGCTCCCGGAAGATCAATAGC TTCTTCTGCGATATCCCTCCACTGCTGGCCATCTCGTGCAGTGACACCAGTCTCAATGAA CTCCTTCTCTTCGCCATCTGTGGCTTCATCCAGACAGCCACGGTGTTAGCTATCACGGTG TCTTATGGCTTCATCGCTGGGGCTGTGATCCACATGCGCTCGGTCGAGGGCAGTCGGCGA GCAGCCTCCACCGGTGGTTCCCACCTCACAGCCGTGGCCATGATGTACGGGACACTCATT TTCATGTACCTGCGCCCCAGCTCCAGCTATGCCCTGGACACTGACAAGATGGCCTCTGTG TTCTATACCCTGGTCATCCCGTCTCTCAACCCACTCATCTACAGCCTCCGCAATAAGGAG GTCAAGGAGGCCCTCAGGCAGACCTGGAGCCGATTCCACTGTCCAGGGCAGGGGTCCCAG |
| Conceptual translation |
MNSENLTRAAVAPAEFVLLGITNRWDLRVALFLTCLPVYLVSLLGNMGMALLIRMDARLH TPMYFFLANLSLLDACYSSAIGPKMLVDLLLPRATIPYTACALQMFVFAGLADTECCLLA AMAYDRYVAIRNPLLYTTAMSQRLCLALLGASGLGGAVSAFVHTTLTFRLSFCRSRKINS FFCDIPPLLAISCSDTSLNELLLFAICGFIQTATVLAITVSYGFIAGAVIHMRSVEGSRR AASTGGSHLTAVAMMYGTLIFMYLRPSSSYALDTDKMASVFYTLVIPSLNPLIYSLRNKE VKEALRQTWSRFHCPGQGSQ Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 9 | 100 | -100 | NS | C/G | N/K | 1000GP (YRI, YRI) |
| 9 | 100 | -100 | SYN | T/C | C/C | 1000GP (YRI, YRI) |
| 9 | 125,551,407 | 125,551,406 | Ins(1) | -/T | rs34583184 (DbSNP) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| N5K | R93Q | F161I | R174H | V252M | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | N | R | F | R | V | 98.16 | 0.506 |
| 2 | K | R | F | R | V | 0.92 | 0.506 |
| 3 | N | R | F | H | V | 0.38 | 0.506 |
| 4 | N | R | F | R | M | 0.23 | 0.653 |
| 5 | N | Q | F | R | V | 0.23 | 0.506 |
| 6 | N | R | I | R | V | 0.08 | 0.506 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5C1.aApr07-unspliced | main_exon | 5UTR | chr9 | 122,788,671 | 122,788,933 | + |
| CDS | chr9 | 122,788,933 | 122,789,892 | + | ||
| 3UTR | chr9 | 122,789,892 | 122,789,895 | + | ||