OR5W2 Olfactory Receptor
| Gene Symbol | OR5W21 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | W |
| Pseudogene | No |
| CORP pseudogene probability score | 0.01 (functional) |
| Aliases | OR11-155, HsOR11.11.34 |
| External Ids | HGNC: 15299 GeneBank: AB065520, AF399355, BK004398, NM_001001960 |
| Build #39 labels | OR5W2P, OR5W3P |
| Chromosomal location | 11:55,913,653-55,914,582 (-) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5AP2 | 57.33% | 300 |
| OR5AR1 | 56.68% | 307 |
| OR5C1 | 58.36% | 293 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5W2B | 84% | 310 |
| Mouse | Or5w8 | 80% | 308 |
| Rat | Or8w1 | 80% | 307 |
| Cow | OR5W2D | 83% | 310 |
| Cow | OR5W2B | 80% | 310 |
| Orang | OR8D4 | 53% | 309 |
| Horse | OR5W2F | 80% | 310 |
| Chimp | OR5W1P | 58% | 303 |
Expression evidences
| Source | Accession |
|---|---|
| GNF Atlas2 | gnf1h10904_at |
Sequence information
| Nucleotide sequence |
ATGGACTGGGAAAATTGCTCCTCATTAACTGATTTTTTTCTCTTGGGAATTACCAATAAC CCAGAGATGAAAGTGACCCTATTTGCTGTATTCTTGGCTGTTTATATCATTAATTTCTCA GCAAATCTTGGAATGATAGTTTTAATCAGAATGGATTACCAACTTCACACACCAATGTAT TTCTTCCTCAGTCATCTGTCTTTCTGTGATCTCTGCTATTCTACTGCAACTGGGCCCAAG ATGCTGGTAGATCTACTTGCCAAGAACAAGTCAATACCCTTCTATGGCTGTGCTCTGCAA TTCTTGGTCTTCTGTATCTTTGCAGATTCTGAGTGTCTACTGCTGTCAGTGATGGCCTTT GATCGGTACAAGGCCATCATCAACCCCCTGCTCTATACAGTCAACATGTCTAGCAGAGTG TGCTATCTACTCTTGACTGGGGTTTATCTGGTGGGAATAGCAGATGCTTTGATACATATG ACACTGGCCTTCCGCCTATGCTTCTGTGGGTCTAATGAGATTAATCATTTCTTCTGTGAT ATCCCTCCTCTCTTATTACTCTCTCGCTCAGATACACAGGTCAATGAGTTAGTGTTATTC ACCGTCTTTGGTTTTATTGAACTGAGTACCATTTCAGGAGTTTTCATTTCTTATTGTTAT ATCATCCTATCAGTCTTGGAGATACACTCTGCTGAGGGGAGGTTCAAAGCTCTCTCTACA TGCACTTCCCACTTATCTGCGGTTGCAATTTTCCAGGGAACTCTGCTCTTTATGTATTTC CGGCCAAGTTCTTCCTATTCTCTAGATCAAGATAAAATGACCTCATTGTTTTACACCCTT GTGGTTCCCATGTTGAACCCCCTGATTTATAGCCTGAGGAACAAGGATGTGAAAGAGGCC CTGAAAAAACTGAAAAATAAAATTTTATTT |
| Conceptual translation |
MDWENCSSLTDFFLLGITNNPEMKVTLFAVFLAVYIINFSANLGMIVLIRMDYQLHTPMY FFLSHLSFCDLCYSTATGPKMLVDLLAKNKSIPFYGCALQFLVFCIFADSECLLLSVMAF DRYKAIINPLLYTVNMSSRVCYLLLTGVYLVGIADALIHMTLAFRLCFCGSNEINHFFCD IPPLLLLSRSDTQVNELVLFTVFGFIELSTISGVFISYCYIILSVLEIHSAEGRFKALST CTSHLSAVAIFQGTLLFMYFRPSSSYSLDQDKMTSLFYTLVVPMLNPLIYSLRNKDVKEA LKKLKNKILF Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 55,681,638 | 55,681,638 | NS | A/C | C/G | rs12795560 (DbSNP) |
| 11 | 55,681,416 | 55,681,416 | NS | A/G | F/L | rs17596422 (DbSNP) |
| 11 | 55,681,580 | 55,681,580 | NS | A/G | M/T | rs17596519 (DbSNP) |
| 11 | 55,681,130 | 55,681,130 | NS | A/T | F/Y | rs34573569 (DbSNP) |
| 11 | 55,681,316 | 55,681,316 | NS | C/A | G/V | rs61743020 (DbSNP) |
| 11 | 55,681,149 | 55,681,149 | NS | C/G | V/L | rs62639688 (DbSNP) |
| 11 | 55,681,572 | 55,681,572 | NS | C/G | A/P | rs17148883 (DbSNP) |
| 11 | 55,681,865 | 55,681,865 | NS | C/T | R/H | rs12419022 (DbSNP) |
| 11 | 55,681,643 | 55,681,643 | NS | C/T | R/K | rs12786096 (DbSNP) |
| 11 | 55,681,566 | 55,681,566 | NS | G/A | R/C | rs61749302 (DbSNP) |
| 11 | 55,681,494 | 55,681,494 | NS | G/A | R/C | rs2457239 (DbSNP) |
| 11 | 55,681,942 | 55,681,942 | NS | G/T | F/L | rs17511797 (DbSNP) |
| 11 | 55,681,140 | 55,681,140 | NS | T/C | K/E | rs2457240 (DbSNP) |
| 11 | 55,681,336 | 55,681,336 | SYN | A/G | C/C | rs11231529 (DbSNP) |
| 11 | 55,681,375 | 55,681,375 | SYN | G/T | I/I | rs17511601 (DbSNP) |
| 11 | 55,913,860 | 55,913,860 | SYN | G/A | C/C | 1000GP (CEU, CHBJPT) |
| 11 | 55,914,018 | 55,914,018 | NS | G/A | R/C | 1000GP (CEU, CHBJPT) |
| 11 | 55,914,090 | 55,914,090 | NS | G/A | R/C | 1000GP (CEU, CHBJPT) |
| 11 | 55,913,899 | 55,913,899 | SYN | T/G | I/I | 1000GP (CEU) |
| 11 | 55,913,940 | 55,913,940 | NS | A/G | F/L | 1000GP (CEU) |
| 11 | 55,914,466 | 55,914,466 | NS | G/T | F/L | 1000GP (CEU) |
| 11 | 55,914,389 | 55,914,389 | NS | T/C | H/R | 1000GP (CEU, CHBJPT) |
| 11 | 55,914,104 | 55,914,104 | NS | A/G | M/T | 1000GP (CEU) |
| 11 | 55,913,673 | 55,913,673 | NS | G/C | L/V | 1000GP (CEU) |
| 11 | 55,913,654 | 55,913,654 | NS | A/T | F/Y | 1000GP (CEU, CHBJPT) |
| 11 | 55,913,722 | 55,913,722 | SYN | G/A | P/P | 1000GP (CHBJPT) |
| 11 | 55,914,178 | 55,914,178 | NS | G/T | N/K | 1000GP (CHBJPT) |
| 11 | 55,914,523 | 55,914,523 | SYN | G/A | N/N | 1000GP (CHBJPT) |
| 11 | 100 | -100 | NS | A/T | F/Y | 1000GP (YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | G/A | P/P | 1000GP (YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 55,153,930 | 55,816,828 | CopyNumber | Variation_0308 (DGV) |
| 11 | 54,835,623 | 55,879,426 | CopyNumber | Variation_8690 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| F310Y | L304V | F215L | R189C | R165C | M160T | Y132S | H65R | F39L | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | F | L | F | C | R | M | Y | H | F | 74.04 | 0.022 |
| 2 | Y | L | F | C | C | M | Y | H | F | 10.45 | 0.022 |
| 3 | F | L | F | C | R | M | Y | R | F | 9.75 | 0.022 |
| 4 | F | V | L | C | R | T | Y | H | L | 3.99 | 0.022 |
| 5 | F | L | F | C | R | M | S | H | F | 0.54 | 1.000 |
| 6 | F | L | F | C | C | M | Y | H | F | 0.31 | 0.022 |
| 7 | Y | L | F | C | R | M | Y | H | F | 0.15 | 0.022 |
| 8 | F | V | L | C | R | M | Y | H | L | 0.15 | 0.022 |
| 9 | F | L | F | R | C | M | Y | H | F | 0.15 | 0.023 |
| 10 | F | V | L | C | R | T | Y | H | F | 0.15 | 0.022 |
| 11 | F | L | L | C | R | M | Y | H | F | 0.08 | 0.022 |
| 12 | F | V | L | C | R | T | Y | R | L | 0.08 | 0.022 |
| 13 | F | L | F | C | R | M | Y | H | L | 0.08 | 0.022 |
| 14 | F | V | F | C | R | T | Y | H | L | 0.08 | 0.022 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5W2.aApr07-unspliced | main_exon | 3UTR | chr11 | 55,913,650 | 55,913,653 | - |
| CDS | chr11 | 55,913,653 | 55,914,582 | - | ||