OR5D13 Olfactory Receptor
| Gene Symbol | OR5D131 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | D |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | OR11-142, OR11-148, HsOR11.11.25, ORL3446 |
| External Ids | HGNC: 15280 GeneBank: AB065778, BK004333, BK004394, NM_001001967 ORDB: ORL3446 |
| Build #39 labels | OR5D13 |
| Chromosomal location | 11:55,773,438-55,774,379 (+) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks | Segregating Pseudo Gene, a nonsynonymous SNP in a highly conserved amino-acid (rs297118) |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5D15P | 72.96% | 307 |
| OR5D2P | 69.16% | 308 |
| OR5D3P | 72.26% | 310 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5D13P | 81% | 314 |
| Mouse | Or5d3-ps | 70% | 311 |
| Rat | Or5d45-ps | 66% | 306 |
| Cow | OR5D92P | 71% | 311 |
| Orang | OR8D4 | 49% | 306 |
| Horse | OR5D13B | 81% | 313 |
| Chimp | OR5D15P | 73% | 307 |
Sequence information
| Nucleotide sequence |
ATGATGGCATCTGAAAGAAATCAAAGCAGCACACCCACTTTTATTCTCTTGGGTTTTTCA GAATACCCAGAAATCCAGGTTCCACTCTTTCTGGTTTTCTTGTTCGTCTACACAGTCACT GTAGTGGGGAACTTGGGCATGATAATAATCATCAGACTCAATTCAAAACTCCATACAATC ATGTGCTTTTTCCTTAGTCACTTGTCCTTGACAGACTTCTGTTTTTCCACTGTAGTTACA CCTAAACTGTTGGAGAACTTGGTTGTGGAATACAGAACCATCTCTTTCTCTGGTTGCATC ATGCAATTTTGTTTTGCTTGCATTTTTGGAGTGACAGAAACTTTCATGTTAGCAGCGATG GCTTATGACCGTTTTGTGGCAGTTTGTAAACCCTTGCTGTATACCACTATTATGTCTCAG AAGCTCTGTGCTCTTCTGGTGGCTGGGTCCTATACATGGGGGATAGTGTGCTCCCTGATA CTCACATATTTTCTTCTTGACTTATCGTTTTGTGAATCTACCTTCATAAATAATTTTATC TGTGACCACTCTGTAATTGTTTCTGCCTCCTACTCAGACCCCTATATCAGCCAGAGGCTA TGCTTTATTATTGCCATATTCAATGAGGTGAGCAGCCTAATTATCATTCTGACATCATAT ATGCTTATTTTCACTACCATTATGAAGATGCGATCTGCAAGTGGGCGCCAGAAAACTTTC TCCACCTGTGCCTCCCACCTGACAGCCATCACTATCTTCCATGGAACTATCCTTTTCCTT TACTGTGTTCCTAATCCTAAAACTTCTAGCCTCATAGTTACAGTGGCTTCTGTGTTTTAC ACAGTGGCGATTCCAATGCTGAACCCATTGATCTACAGCCTTAGGAACAAAGATATCAAT AACATGTTTGAAAAATTAGTTGTCACCAAATTGATTTACCAC |
| Conceptual translation |
MMASERNQSSTPTFILLGFSEYPEIQVPLFLVFLFVYTVTVVGNLGMIIIIRLNSKLHTI MCFFLSHLSLTDFCFSTVVTPKLLENLVVEYRTISFSGCIMQFCFACIFGVTETFMLAAM AYDRFVAVCKPLLYTTIMSQKLCALLVAGSYTWGIVCSLILTYFLLDLSFCESTFINNFI CDHSVIVSASYSDPYISQRLCFIIAIFNEVSSLIIILTSYMLIFTTIMKMRSASGRQKTF STCASHLTAITIFHGTILFLYCVPNPKTSSLIVTVASVFYTVAIPMLNPLIYSLRNKDIN NMFEKLVVTKLIYH Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 55,541,014 | 55,541,014 | nonsense SNP | A/T | */L | rs11230980 (DbSNP) |
| 11 | 55,541,284 | 55,541,284 | NS | A/G | H/R | rs11230983 (DbSNP) |
| 11 | 55,541,098 | 55,541,098 | NS | G/A | C/Y | rs297118 (DbSNP) |
| 11 | 55,541,620 | 55,541,620 | NS | G/T | R/L | rs7124871 (DbSNP) |
| 11 | 55,541,807 | 55,541,807 | SYN | C/T | D/D | rs17147848 (DbSNP) |
| 11 | 55,773,488 | 55,773,488 | NS | G/T | L/F | 1000GP (CEU) |
| 11 | 55,773,808 | 55,773,808 | NS | G/A | R/H | 1000GP (CEU, CHBJPT) |
| 11 | 55,774,144 | 55,774,144 | NS | G/T | R/L | 1000GP (CEU) |
| 11 | 55,773,622 | 55,773,622 | NS | G/A | C/Y | 1000GP (CEU, CHBJPT) |
| 11 | 55,773,823 | 55,773,823 | NS | G/T | C/F | 1000GP (CHBJPT) |
| 11 | 55,774,029 | 55,774,029 | nonsense SNP | C/T | Q/* | 1000GP (CHBJPT) |
| 11 | 55,774,331 | 55,774,331 | SYN | T/C | D/D | 1000GP (CHBJPT) |
| 11 | 100 | -100 | NS | G/A | C/Y | 1000GP (YRI, YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 55,153,930 | 55,816,828 | CopyNumber | Variation_0308 (DGV) |
| 11 | 55,475,356 | 55,563,900 | CopyNumber | Variation_1244 (DGV) |
| 11 | 55,446,295 | 55,618,623 | CopyNumber | Variation_2167 (DGV) |
| 11 | 55,339,702 | 55,638,112 | CopyNumber | Variation_2926 (DGV) |
| 11 | 55,222,420 | 55,621,884 | CopyNumber | Variation_3852 (DGV) |
| 11 | 55,382,681 | 55,548,038 | CopyNumber | Variation_4743 (DGV) |
| 11 | 54,835,623 | 55,879,426 | CopyNumber | Variation_8690 (DGV) |
| 11 | 55,445,294 | 55,620,699 | CopyNumber | Variation_9187 (DGV) |
| 11 | 55,377,006 | 55,620,699 | CopyNumber | Variation_9188 (DGV) |
| 11 | 55,422,586 | 55,596,313 | CopyNumber | Variation_10360 (DGV) |
| 11 | 55,422,585 | 55,596,313 | CopyNumber | Variation_29911 (DGV) |
| 11 | 55,460,683 | 55,547,092 | CopyNumber | Variation_38236 (DGV) |
| 11 | 55,463,782 | 55,584,109 | CopyNumber | Variation_48056 (DGV) |
| 11 | 55,437,126 | 55,596,313 | CopyNumber | Variation_48840 (DGV) |
| 11 | 55,442,368 | 55,596,313 | CopyNumber | Variation_48841 (DGV) |
| 11 | 55,444,868 | 55,591,047 | CopyNumber | Variation_48842 (DGV) |
| 11 | 55,444,868 | 55,596,313 | CopyNumber | Variation_48843 (DGV) |
| 11 | 55,447,427 | 55,596,313 | CopyNumber | Variation_53429 (DGV) |
| 11 | 55,422,345 | 55,603,590 | CopyNumber | Variation_65956 (DGV) |
| 11 | 55,523,241 | 55,558,796 | CopyNumber | Variation_85784 (DGV) |
| 11 | 55,540,814 | 55,543,855 | Deletion | #287 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| L17F | V36I | C62Y | A118T | R124H | Q198* | R236L | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | L | V | Y | A | R | Q | R | 82.49 | 0.534 |
| 2 | L | V | Y | A | H | Q | R | 9.68 | 0.953 |
| 3 | L | V | C | A | R | Q | R | 3.23 | 0.946 |
| 4 | L | V | Y | A | R | Q | L | 2.84 | 0.486 |
| 5 | L | V | Y | A | R | * | R | 0.69 | 1.200 |
| 6 | L | I | Y | A | R | Q | R | 0.61 | 0.534 |
| 7 | L | V | Y | T | R | Q | R | 0.15 | 0.534 |
| 8 | L | I | Y | A | H | Q | R | 0.15 | 0.953 |
| 9 | F | V | Y | A | R | Q | R | 0.15 | 0.534 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5D13.aApr07-unspliced | main_exon | CDS | chr11 | 55,773,438 | 55,774,379 | + |
| 3UTR | chr11 | 55,774,379 | 55,774,382 | + | ||