OR5H15 Olfactory Receptor
| Gene Symbol | OR5H151 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | H |
| Pseudogene | No |
| CORP pseudogene probability score | 0.03 (functional) |
| Aliases | HsOR3.3.6 |
| External Ids | HGNC: 31287 GeneBank: NM_001005515 |
| Build #39 labels | |
| Chromosomal location | 3:98,168,700-98,169,638 (+) |
| Cluster | 3@98 |
| Synteny | CLIC#9 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5H1 | 94.57% | 313 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5H13 | 76% | 308 |
| Mouse | Or5h26 | 75% | 308 |
| Rat | Or5h26 | 74% | 308 |
| Cow | OR5H13 | 77% | 308 |
| Orang | OR5H8 | 85% | 309 |
| Orang | OR5H8BP | 82% | 257 |
| Horse | OR5H40 | 77% | 309 |
| Chimp | OR5H1 | 93% | 308 |
| Chimp | OR5H1B | 93% | 302 |
Sequence information
| Nucleotide sequence |
ATGGAAGAGGAAAATGCAACATTGCTGACAGAGTTTGTTCTCACAGGATTTTTATATCAA CCACAGTGGAAAATACCCCTGTTCTTGGCATTCTTGGTAATATATCTCATCACCATCATG GGGAATCTTGGTCTGATTGCTGTCATCTGGAAAGACCCTCACCTTCATATCCCAATGTAC TTACTCCTTGGGAATTTAGCTTTTGTGGATGCTTGGATATCATCCACAGTGACCCCAAAG ATGCTGAATAACTTCTTAGCTAAGAGTAAGATGATATCTCTCTCTGAATGCAAGATACAA TTTTTTTCCATTGCAATTGGCGTAACCACAGAATGTTTTCTCTTGGCAACAATGGCATAT GATCGCTATGTAGCCATATGCAAACCTTTACTTTATCCAGCCATTATGACCAATGGACTG TGCATCCGGCTATTAATCTTGTCATATATAGCTGGTATTCTTCATGCTTTAATCCATGAA GGATTTTTATTCAGACTAACCTTCTGTAACTCCAACATAGTACATCACATTTACTGTGAC ACTATCCCATTGTCTAAGATTTCTTGTACTGATTCTTCTATTAATTTTCTAATGGTTTTT ATTTTCTCAGGTTCAATTCAGGTATTCAGCATTGTGACTATTCTTATATCTTACACATTT GTTCTCTTCACAGTCTTAGAAAAGAAATCTGATAAGGGTGTAAGGAAAGCCTTTTCCACC TGTGGAGCCCATCTCTTCTCTGTCTGTTTATACTATGGCCCCCTTCTCTTAATGTATGTG GGCCCTGCATCTCCGCAAGCAGATGGTCAAAATATGGTGGAGCCTCTATTCTACACTGTC ATCATTCCTTTGTTAAATCCTATCATCTACAGTCTGAGAAATAAGCAAGTCATAGTTTCA TTCATAAAAATGTTAAAAAGAAATGTTAAGGTTTCATAC |
| Conceptual translation |
MEEENATLLTEFVLTGFLYQPQWKIPLFLAFLVIYLITIMGNLGLIAVIWKDPHLHIPMY LLLGNLAFVDAWISSTVTPKMLNNFLAKSKMISLSECKIQFFSIAIGVTTECFLLATMAY DRYVAICKPLLYPAIMTNGLCIRLLILSYIAGILHALIHEGFLFRLTFCNSNIVHHIYCD TIPLSKISCTDSSINFLMVFIFSGSIQVFSIVTILISYTFVLFTVLEKKSDKGVRKAFST CGAHLFSVCLYYGPLLLMYVGPASPQADGQNMVEPLFYTVIIPLLNPIIYSLRNKQVIVS FIKMLKRNVKVSY Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 3 | 97,888,422 | 97,888,421 | Ins(1) | -/G | rs34583971 (DbSNP) | |
| 3 | 97,888,324 | 97,888,323 | Ins(1) | -/G | rs35671483 (DbSNP) | |
| 3 | 97,888,323 | 97,888,322 | Ins(1) | -/G | rs11408838 (DbSNP) | |
| 3 | 97,868,973 | 97,868,973 | large insertion | 18856bp insertion | rs72487696 (DbSNP) | |
| 3 | 97,888,000 | 97,888,000 | NS | A/C | I/L | rs62266797 (DbSNP) |
| 3 | 97,887,865 | 97,887,865 | NS | A/G | I/V | rs4133320 (DbSNP) |
| 3 | 97,888,060 | 97,888,060 | NS | A/G | I/V | rs62266798 (DbSNP) |
| 3 | 97,888,216 | 97,888,216 | NS | A/G | I/V | rs62266807 (DbSNP) |
| 3 | 97,887,991 | 97,887,991 | NS | A/G | I/V | rs62269706 (DbSNP) |
| 3 | 97,888,042 | 97,888,042 | NS | A/T | T/S | rs4133322 (DbSNP) |
| 3 | 97,887,985 | 97,887,985 | NS | A/T | T/S | rs4133321 (DbSNP) |
| 3 | 97,887,997 | 97,887,997 | NS | C/G | R/G | rs62266796 (DbSNP) |
| 3 | 97,888,172 | 97,888,172 | NS | C/G | T/S | rs62266803 (DbSNP) |
| 3 | 97,888,438 | 97,888,438 | NS | C/G | L/V | rs72487748 (DbSNP) |
| 3 | 97,887,995 | 97,887,995 | NS | C/G | A/G | rs62269707 (DbSNP) |
| 3 | 97,888,085 | 97,888,085 | NS | C/T | T/I | rs62266800 (DbSNP) |
| 3 | 97,888,337 | 97,888,337 | NS | C/T | P/L | rs13082608 (DbSNP) |
| 3 | 97,888,178 | 97,888,178 | NS | G/T | G/V | rs62266804 (DbSNP) |
| 3 | 97,887,970 | 97,887,970 | SYN | A/C | R/R | rs72933946 (DbSNP) |
| 3 | 97,888,164 | 97,888,164 | SYN | A/G | Q/Q | rs62266801 (DbSNP) |
| 3 | 97,888,167 | 97,888,167 | SYN | A/T | V/V | rs62266802 (DbSNP) |
| 3 | 97,888,212 | 97,888,212 | SYN | C/T | F/F | rs62266806 (DbSNP) |
| 3 | 97,888,197 | 97,888,197 | SYN | C/T | Y/Y | rs7623031 (DbSNP) |
| 3 | 97,888,068 | 97,888,068 | SYN | C/T | H/H | rs62266799 (DbSNP) |
| 3 | 97,888,206 | 97,888,206 | SYN | C/T | V/V | rs62266805 (DbSNP) |
| 3 | 98,169,458 | 98,169,458 | SYN | C/A | G/G | 1000GP (CEU) |
| 3 | 98,169,021 | 98,169,021 | NS | G/A | V/I | 1000GP (CEU, CHBJPT) |
| 3 | 98,169,493 | 98,169,493 | NS | C/T | P/L | 1000GP (CEU, CHBJPT) |
| 3 | 98,169,353 | 98,169,353 | SYN | C/T | Y/Y | 1000GP (CEU, CHBJPT) |
| 3 | 98,169,594 | 98,169,594 | NS | G/C | V/L | 1000GP (CHBJPT) |
| 3 | 100 | -100 | SYN | C/T | G/G | 1000GP (YRI, YRI) |
| 3 | 100 | -100 | NS | G/A | V/I | 1000GP (YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 3 | 97,887,491 | 97,919,363 | CopyNumber | Variation_37833 (DGV) |
| 3 | 97,874,279 | 97,931,369 | CopyNumber | Variation_62080 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| C97Y | I104F | I106T | V108I | N138T | S148T | T167S | P265L | I288V | V299L | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | C | I | I | V | N | S | T | P | I | V | 35.02 | 0.084 |
| 2 | C | I | I | I | N | T | S | L | I | V | 31.34 | 0.084 |
| 3 | C | I | I | I | N | T | S | P | I | V | 24.73 | 0.084 |
| 4 | C | I | I | V | N | S | T | P | I | L | 3.53 | 0.084 |
| 5 | C | F | I | V | N | S | T | P | I | V | 1.69 | 0.084 |
| 6 | C | I | I | I | N | S | T | P | I | V | 1.00 | 0.084 |
| 7 | C | I | I | I | N | T | S | L | V | V | 0.84 | 0.084 |
| 8 | C | I | I | I | T | T | S | P | I | V | 0.31 | 0.084 |
| 9 | C | I | I | V | N | T | S | L | I | V | 0.31 | 0.084 |
| 10 | Y | I | I | V | N | S | T | P | I | V | 0.31 | 0.883 |
| 11 | C | I | I | I | N | S | S | L | I | V | 0.15 | 0.084 |
| 12 | C | F | I | V | N | S | S | P | I | V | 0.15 | 0.084 |
| 13 | Y | I | I | I | N | T | S | L | I | V | 0.15 | 0.883 |
| 14 | C | I | I | I | N | S | S | P | I | V | 0.08 | 0.084 |
| 15 | C | F | I | V | N | T | S | L | I | V | 0.08 | 0.084 |
| 16 | C | I | T | I | N | T | S | P | I | V | 0.08 | 0.084 |
| 17 | C | I | I | V | N | S | S | P | I | V | 0.08 | 0.084 |
| 18 | C | I | I | V | N | S | T | L | I | V | 0.08 | 0.084 |
| 19 | C | I | I | V | N | T | S | P | I | V | 0.08 | 0.084 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5H15.aApr07-unspliced | main_exon | CDS | chr3 | 98,168,700 | 98,169,638 | + |
| 3UTR | chr3 | 98,169,638 | 98,169,641 | + | ||