OR5M3 Olfactory Receptor
| Gene Symbol | OR5M31 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | M |
| Pseudogene | No |
| CORP pseudogene probability score | 0.07 (functional) |
| Aliases | OR11-191, HsOR11.11.70, ORL3316, ORL3314 |
| External Ids | HGNC: 14806 GeneBank: AB065746, AF399518, BK004498, NM_001004742 ORDB: ORL3316, ORL3314 |
| Build #39 labels | OR5M3 |
| Chromosomal location | 11:56,469,577-56,470,497 (-) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5M4P | 94.81% | 308 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5M3C | 83% | 306 |
| Dog | OR5M9 | 80% | 306 |
| Mouse | Or5m3 | 92% | 306 |
| Mouse | Or5m3b | 90% | 306 |
| Rat | Or5m3 | 92% | 306 |
| Cow | OR5M3DP | 87% | 305 |
| Orang | OR5E1P | 51% | 302 |
| Horse | OR5M3E | 89% | 307 |
| Chimp | OR5M3P | 95% | 307 |
| Chimp | OR5M3DP | 93% | 307 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136983 |
Sequence information
| Nucleotide sequence |
ATGCTCAATTTCACCGATGTGACAGAGTTCATTCTTTTGGGGCTAACGAGCCGTCGAGAA TGGCAAGTTCTCTTCTTCATCATCTTTCTTGTGGTCTACATCATCACCATGGTGGGCAAT ATCGGCATGATGGTGTTAATCAAGGTCAGTCCTCAGCTTAACAACCCCATGTACTTTTTC CTCAGTCACTTGTCATTTGTTGATGTGTGGTTTTCTTCCAATGTCACCCCTAAAATGTTG GAAAACCTGTTATCAGATAAAAAAACAATTACTTATGCTGGTTGTTTAGTACAGTGTTTC TTCTTCATTGCTCTTGTCCATGTGGAAATTTTTATTCTTGCTGCGATGGCCTTTGATAGA TACATGGCAATTGGGAATCCTCTGCTTTATGGCAGTAAAATGTCAAGGGTTGTCTGTATT CGACTGATTACTTTCCCTTACATTTATGGTTTTCTGACGAGTCTGGCAGCAACATTATGG ACTTACGGCTTGTACTTCTGTGGAAAAATTGAGATCAACCATTTCTACTGTGCAGATCCA CCTCTCATCAAAATGGCCTGTGCTGGGACCTTTGTAAAAGAATATACAATGATCATACTT GCCGGCATTAACTTCACATATTCCCTGACTGTAATTATCATCTCTTACTTATTCATCCTC ATTGCCATTCTGCGAATGCGCTCAGCAGAAGGAAGGCAGAAGGCCTTTTCCACATGTGGG TCCCATCTGACAGCTGTCATTATATTCTATGGTACTCTGATCTTCATGTATCTCAGACGT CCCACAGAGGAGTCTGTGGAGCAGGGGAAGATGGTGGCTGTGTTCTATACCACAGTGATC CCCATGTTGAATCCCATGATCTACAGTCTGAGGAACAAGGATGTGAAAAAGGCCATGATG AAAGTGATCAGCAGATCATGT |
| Conceptual translation |
MLNFTDVTEFILLGLTSRREWQVLFFIIFLVVYIITMVGNIGMMVLIKVSPQLNNPMYFF LSHLSFVDVWFSSNVTPKMLENLLSDKKTITYAGCLVQCFFFIALVHVEIFILAAMAFDR YMAIGNPLLYGSKMSRVVCIRLITFPYIYGFLTSLAATLWTYGLYFCGKIEINHFYCADP PLIKMACAGTFVKEYTMIILAGINFTYSLTVIIISYLFILIAILRMRSAEGRQKAFSTCG SHLTAVIIFYGTLIFMYLRRPTEESVEQGKMVAVFYTTVIPMLNPMIYSLRNKDVKKAMM KVISRSC Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 56,237,553 | 56,237,553 | nonsense SNP | A/G | */R | rs72911641 (DbSNP) |
| 11 | 56,237,722 | 56,237,722 | NS | A/T | F/L | rs605734 (DbSNP) |
| 11 | 56,237,564 | 56,237,564 | NS | A/T | V/D | rs61902880 (DbSNP) |
| 11 | 56,237,487 | 56,237,487 | NS | C/T | G/S | rs17150664 (DbSNP) |
| 11 | 56,237,578 | 56,237,578 | SYN | A/G | S/S | rs61902881 (DbSNP) |
| 11 | 56,237,410 | 56,237,410 | SYN | G/A | A/A | rs617315 (DbSNP) |
| 11 | 56,469,934 | 56,469,934 | SYN | A/G | A/A | 1000GP (CEU) |
| 11 | 56,470,246 | 56,470,246 | NS | T/A | L/F | 1000GP (CEU, CHBJPT) |
| 11 | 56,470,252 | 56,470,252 | SYN | G/A | N/N | 1000GP (CEU) |
| 11 | 56,470,011 | 56,470,011 | NS | C/T | G/S | 1000GP (CHBJPT) |
| 11 | 100 | -100 | NS | T/A | L/F | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 30 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| G163S | T158S | L84F | V32A | N3S | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | G | T | L | V | N | 77.80 | 0.033 |
| 2 | G | T | F | V | N | 15.36 | 0.033 |
| 3 | G | T | L | V | S | 4.69 | 0.033 |
| 4 | S | T | L | V | N | 1.92 | 0.033 |
| 5 | G | T | L | A | N | 0.15 | 0.033 |
| 6 | G | S | L | V | N | 0.08 | 0.033 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5M3.aApr07-unspliced | main_exon | 3UTR | chr11 | 56,469,574 | 56,469,577 | - |
| CDS | chr11 | 56,469,577 | 56,470,497 | - | ||