OR5M9 Olfactory Receptor
| Gene Symbol | OR5M91 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | M |
| Pseudogene | No |
| CORP pseudogene probability score | 0.51 (pseudogene) |
| Aliases | OR11-190, HsOR11.11.69, ORL3384 |
| External Ids | HGNC: 15294 GeneBank: AB065747, AF399519, BK004497, NM_001004743 ORDB: ORL3384 |
| Build #39 labels | OR5M9 |
| Chromosomal location | 11:56,462,472-56,463,401 (-) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5M3 | 76.8% | 306 |
| OR5M4P | 75.24% | 307 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5M3 | 80% | 306 |
| Mouse | Or5m9 | 90% | 310 |
| Mouse | Or5m9b | 89% | 310 |
| Rat | Or5m9 | 90% | 310 |
| Cow | OR5M9DP | 87% | 305 |
| Cow | OR5M9CP | 85% | 310 |
| Orang | OR5AU1 | 51% | 297 |
| Horse | OR5M9l | 90% | 310 |
| Horse | OR5M9M | 88% | 310 |
| Chimp | OR5M3P | 74% | 306 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC140458 |
Sequence information
| Nucleotide sequence |
ATGCCTAATTTCACGGATGTGACAGAATTTACTCTCCTGGGGCTGACCTGTCGTCAGGAG CTACAGGTTCTCTTTTTTGTGGTGTTCCTAGCGGTTTACATGATCACTCTGTTGGGAAAT ATTGGTATGATCATTTTGATTAGCATCAGTCCTCAGCTTCAGAGTCCCATGTACTTTTTC CTGAGTCATCTGTCTTTTGCGGACGTGTGCTTCTCCTCCAACGTTACCCCCAAAATGCTG GAAAACTTATTATCAGAGACAAAAACCATTTCCTATGTGGGATGCTTGGTGCAGTGCTAC TTTTTCATTGCCGTTGTCCACGTGGAGGTCTATATCCTGGCTGTGATGGCCTTTGACAGG TACATGGCCGGCTGCAACCCTCTGCTTTATGGCAGTAAAATGTCTAGGACTGTGTGTGTT CGGCTCATCTCTGTGCCTTATGTCTATGGATTCTCTGTCAGCCTAATATGCACACTATGG ACTTATGGCTTATACTTCTGTGGAAACTTTGAAATCAATCACTTCTATTGTGCAGATCCC CCTCTCATCCAGATTGCCTGTGGGAGAGTGCACATCAAAGAAATCACAATGATTGTTATT GCTGGAATTAACTTCACATATTCCCTCTCGGTGGTCCTCATCTCCTACACTCTCATTGTA GTAGCTGTGCTACGCATGCGCTCTGCCGATGGCAGGAGGAAGGCGTTCTCCACCTGTGGG TCCCACTTGACGGCTGTTTCTATGTTTTATGGGACCCCCATCTTCATGTATCTCAGGAGA CCCACTGAGGAATCCGTAGAGCAGGGCAAAATGGTGGCTGTGTTTTACACCACAGTAATT CCTATGTTGAATCCCATGATCTACAGTCTGAGAAATAAGGATGTAAAAGAAGCAGTCAAC AAAGCAATCACCAAGACATATGTGAGGCAG |
| Conceptual translation |
MPNFTDVTEFTLLGLTCRQELQVLFFVVFLAVYMITLLGNIGMIILISISPQLQSPMYFF LSHLSFADVCFSSNVTPKMLENLLSETKTISYVGCLVQCYFFIAVVHVEVYILAVMAFDR YMAGCNPLLYGSKMSRTVCVRLISVPYVYGFSVSLICTLWTYGLYFCGNFEINHFYCADP PLIQIACGRVHIKEITMIVIAGINFTYSLSVVLISYTLIVVAVLRMRSADGRRKAFSTCG SHLTAVSMFYGTPIFMYLRRPTEESVEQGKMVAVFYTTVIPMLNPMIYSLRNKDVKEAVN KAITKTYVRQ Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 56,230,120 | 56,230,120 | NS | A/G | L/P | rs61902868 (DbSNP) |
| 11 | 56,230,678 | 56,230,678 | NS | A/G | V/A | rs61902871 (DbSNP) |
| 11 | 56,230,328 | 56,230,328 | NS | G/T | Q/K | rs61902869 (DbSNP) |
| 11 | 56,230,069 | 56,230,069 | NS | T/C | K/R | rs1945237 (DbSNP) |
| 11 | 56,230,473 | 56,230,473 | SYN | A/G | S/S | rs61902870 (DbSNP) |
| 11 | 56,462,852 | 56,462,852 | NS | G/T | Q/K | 1000GP (CEU) |
| 11 | 56,462,644 | 56,462,644 | NS | G/A | P/L | 1000GP (CEU) |
| 11 | 56,462,593 | 56,462,593 | NS | T/C | K/R | 1000GP (CEU) |
| 11 | 56,462,997 | 56,462,997 | SYN | A/G | S/S | 1000GP (CEU) |
| 11 | 56,463,135 | 56,463,135 | SYN | G/T | T/T | 1000GP (CEU) |
| 11 | 56,463,202 | 56,463,202 | NS | G/A | A/V | 1000GP (CEU) |
| 11 | 56,462,769 | 56,462,769 | SYN | C/T | V/V | 1000GP (CEU) |
| 11 | 100 | -100 | NS | G/A | P/L | 1000GP (YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | A/G | S/S | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 121 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| L290M | K270R | T262S | P253L | L209V | N204D | C187Y | Q184K | S154C | G124D | V97M | A67V | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | L | K | T | P | L | N | C | Q | S | G | V | A | 86.18 | 0.250 |
| 2 | L | R | T | L | L | N | C | K | S | G | V | V | 4.53 | 0.250 |
| 3 | L | K | T | L | L | N | C | K | S | G | V | V | 3.92 | 0.250 |
| 4 | L | K | T | P | L | N | C | Q | S | G | V | V | 3.07 | 0.250 |
| 5 | L | K | T | P | L | D | C | Q | S | G | V | V | 0.54 | 0.250 |
| 6 | M | K | T | P | L | N | C | Q | S | G | V | A | 0.31 | 0.250 |
| 7 | L | K | T | P | L | N | Y | Q | S | G | V | V | 0.31 | 0.257 |
| 8 | L | K | T | P | L | N | C | Q | C | G | V | A | 0.15 | 0.250 |
| 9 | L | K | T | L | L | N | C | K | S | G | V | A | 0.15 | 0.250 |
| 10 | L | K | T | P | L | N | C | Q | S | G | M | A | 0.15 | 0.250 |
| 11 | L | K | T | P | V | N | C | Q | S | G | V | A | 0.15 | 0.250 |
| 12 | L | R | T | L | L | N | C | K | S | G | V | A | 0.15 | 0.250 |
| 13 | L | K | T | P | L | D | C | Q | S | G | V | A | 0.08 | 0.250 |
| 14 | L | R | T | P | L | N | C | Q | S | D | V | A | 0.08 | 0.250 |
| 15 | L | R | T | P | L | N | C | Q | S | G | V | A | 0.08 | 0.250 |
| 16 | L | K | S | P | L | N | C | Q | S | G | V | A | 0.08 | 0.250 |
| 17 | L | R | T | P | L | N | C | K | S | G | V | V | 0.08 | 0.250 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5M9.aApr07-unspliced | main_exon | 3UTR | chr11 | 56,462,469 | 56,462,472 | - |
| CDS | chr11 | 56,462,472 | 56,463,401 | - | ||