OR6C65 Olfactory Receptor
| Gene Symbol | OR6C651 (View this gene in GeneCards) |
| Family | 6 |
| Subfamily | C |
| Pseudogene | No |
| CORP pseudogene probability score | 0.92 (pseudogene) |
| Aliases | HsOR12.5.17 |
| External Ids | HGNC: 31295 GeneBank: NM_001005518 |
| Build #39 labels | |
| Chromosomal location | 12:55,400,529-55,401,464 (+) |
| Cluster | 12@56 |
| Synteny | CLIC#31 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR6C66P | 76.62% | 308 |
| OR6C75 | 72.76% | 312 |
| OR6C76 | 74.36% | 312 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR6C75C | 71% | 306 |
| Mouse | Or6c65 | 83% | 312 |
| Rat | Or6c65-ps | 76% | 312 |
| Cow | OR6C76 | 75% | 308 |
| Orang | OR6C65P | 93% | 295 |
| Orang | OR6C65BP | 90% | 272 |
| Horse | OR6C66 | 78% | 311 |
| Chimp | OR6C74 | 69% | 306 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136899 |
Sequence information
| Nucleotide sequence |
ATGCCAAATATGACATCAATTAGAGAATTCATTCTTCTGGGATTTACAGATAACCCAGAG TTACAAGTTGTGATATTCTTCTTTATGTTGATCACATACTTATTGAGTGTAAGTGGAAAC ATGATCATCATTATGTTAACATTGTCAAATATTCATTTGAAAACTCCTATGTATTTCTTC CTCAGGAATTTCTCTTTCTTAGAAATTTCATTTACGACAGTCTTCATTCCTAGATTTCTG ATCAACATTGCTACAGGAGACACAACCATTTCCTATAATGCTTCCATGGCCCAAGTATTT TTTTTAATTCTTTTGGGATCAACAGAATTTTTTCTTCTGGCTGTCATGTCTTATGATCGC TATGTGGCTATCTGCAAACCTCTACATTATACAACCATCATGAGTAACAAAGTCTGTAAT TGGCTTGTAATCAGCTCCTGGCTGGCTGGTTTTCTCATTATTTTTCCCCCCGTGATTATG GGCCTCCAACTGGATTTTTGTGACTCCAGCACTATTGACCATTTCATCTGTGATTCTTCC CCTATGCTGCTGATTGCTTGCACAGACACACAGTTTCTAGAGCTTATGGCATTTTTGCTA GCAGTATTCACACTCATGGTAACTTTGGCCTTGGTGGTTCTCTCCTACACACTCATCCTT AAAACAATTCTGAAGATTCCCTCTGCCCAGCAAAGGAAAAAGGCTTTTTCAACTTGTTCC TCCCATATGATTGTGGTTTCTGTTTCTTATGGGAGTTGCATTTTTATGTGTGTAAAAACA TCTGCAAAAGAAGGTATGGCTTTGAGCAAAGGTGTAGCAGTGCTTAATACCTCTGTTGCT CCTATGTTGAATCCCTTTATTTATACCTTAAGAAACCAGCAGGTGAAACAGGCCCTTAGG GAATTCACCAAAAAAATATTATCATTGAACAAGCAA |
| Conceptual translation |
MPNMTSIREFILLGFTDNPELQVVIFFFMLITYLLSVSGNMIIIMLTLSNIHLKTPMYFF LRNFSFLEISFTTVFIPRFLINIATGDTTISYNASMAQVFFLILLGSTEFFLLAVMSYDR YVAICKPLHYTTIMSNKVCNWLVISSWLAGFLIIFPPVIMGLQLDFCDSSTIDHFICDSS PMLLIACTDTQFLELMAFLLAVFTLMVTLALVVLSYTLILKTILKIPSAQQRKKAFSTCS SHMIVVSVSYGSCIFMCVKTSAKEGMALSKGVAVLNTSVAPMLNPFIYTLRNQQVKQALR EFTKKILSLNKQ Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 12 | 100 | -100 | NS | A/G | T/A | 1000GP (YRI) |
| 12 | 100 | -100 | SYN | A/G | Q/Q | 1000GP (YRI, YRI, YRI) |
| 12 | 55,401,192 | 55,401,192 | NS | A/G | T/A | 1000GP (CEU, CHBJPT) |
| 12 | 55,794,343 | 55,794,343 | NS | A/C | I/L | rs61741338 (DbSNP) |
| 12 | 55,794,350 | 55,794,350 | NS | A/T | Q/L | rs12424958 (DbSNP) |
| 12 | 55,794,976 | 55,794,976 | NS | A/G | T/A | rs7971073 (DbSNP) |
| 12 | 55,795,231 | 55,795,231 | SYN | C/T | L/L | rs61744496 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 16 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| T222A | % Freq | CORP | |
|---|---|---|---|
| 1 | A | 75.50 | 0.934 |
| 2 | T | 24.50 | 0.934 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR6C65.aApr07-unspliced | main_exon | CDS | chr12 | 55,400,529 | 55,401,464 | + |
| 3UTR | chr12 | 55,401,464 | 55,401,467 | + | ||