OR6C68 Olfactory Receptor
| Gene Symbol | OR6C681 (View this gene in GeneCards) |
| Family | 6 |
| Subfamily | C |
| Pseudogene | No |
| CORP pseudogene probability score | 1 (pseudogene) |
| Aliases | HsOR12.5.21 |
| External Ids | HGNC: 31297 GeneBank: NM_001005519 |
| Build #39 labels | |
| Chromosomal location | 12:55,492,363-55,493,313 (+) |
| Cluster | 12@56 |
| Synteny | CLIC#31 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR6C2 | 74.68% | 312 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR6C35 | 78% | 311 |
| Mouse | Or6c68 | 84% | 312 |
| Rat | Or6c68 | 82% | 312 |
| Cow | OR6C268 | 81% | 311 |
| Orang | OR6C68P | 94% | 295 |
| Horse | OR6C268 | 83% | 305 |
| Chimp | OR6C74 | 64% | 306 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | EB388040 |
Sequence information
| Nucleotide sequence |
ATGCAGAAGTCAGTAATGAGAAAACACACAGCAATAACAACATTCATCCTTCTGGGACTG ACAGAAGATCCTCAGCTGCAGGTTCTGCTTTTCATGTTTCTATTTATCACCTACATGTTG AGTGTAACAGGGAAACTGACCATTATCGCCCTCACCATGTTGGATCCCCACCTGAAAACA CCCATGTATTTTTTTCTCCAAAATTTATCTTTCTTAGAAATCTCATTTACAGCTACCTGT GTTCCAAGATTCTTATACAGTATCTCAACTGGGAACAAAATAATAACGTATAATGCATGT GTCATTCAGCTATTTTTTGCAGACCTCTTTGGGGTAACTGAATTTTTTCTTTTGGCTACC ATGTCATATGATCGCTATGTGGCCATCTGCAAACCCTTGCATTATATGGCAATCATGAGC AACAAAGTGTGCAAAACAATGGTTATTTGTTGTTGGATGGCAGCACTTATGATTATCCTC CCACCACTTAGCTTAGGTTTTCATCTAGAATTCTGTGACTCTAATGTCATCAATCATTTT GGCTGTGATGCATTGCCTATTCTGAAAATACCATGCTCAGACACATCATTAATTGAGCAG ATGGTTGTAGCCTCTGCTGTATTAACCTTTATTATCACTCTTGTATGTGTAGTTCTGTCC TACACATATATCATAAGAACAATTCTAAAATTCCCTTCTGTTCAACAAAAGAAAAAAGCC TTTTCTACCTGTTCTTCACATATTACTGTGGTTTCCATCACTTATGGCAGCTGCATCTTC ATCTATATCAAGCCATCTGCAAAAGAAGAGGTAAACATTAATAAAGGTGTGTCAGTGCTT ATTTCATCCATATCACCTATGTTGAATTCTTTCATATATACTCTTAGGAATGAGCAAGTT AAACAAGCCTTTCATGACTCACTCAAAAAAATTGCATTTCGTTTAAAAAAG |
| Conceptual translation |
MRKHTAITTFILLGLTEDPQLQVLLFMFLFITYMLSVTGKLTIIALTMLDPHLKTPMYFF LQNLSFLEISFTATCVPRFLYSISTGNKIITYNACVIQLFFADLFGVTEFFLLATMSYDR YVAICKPLHYMAIMSNKVCKTMVICCWMAALMIILPPLSLGFHLEFCDSNVINHFGCDAL PILKIPCSDTSLIEQMVVASAVLTFIITLVCVVLSYTYIIRTILKFPSVQQKKKAFSTCS SHITVVSITYGSCIFIYIKPSAKEEVNINKGVSVLISSISPMLNSFIYTLRNEQVKQAFH DSLKKIAFRLKK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 12 | 55,886,276 | 55,886,275 | Ins(1) | -/G | rs36002641 (DbSNP) | |
| 12 | 55,886,294 | 55,886,294 | NS | A/G | T/A | rs7133698 (DbSNP) |
| 12 | 55,886,489 | 55,886,489 | NS | A/T | I/F | rs7304753 (DbSNP) |
| 12 | 55,887,054 | 55,887,054 | NS | C/G | A/G | rs56760228 (DbSNP) |
| 12 | 55,886,652 | 55,886,652 | NS | C/T | P/L | rs61747528 (DbSNP) |
| 12 | 55,887,087 | 55,887,087 | NS | G/T | R/L | rs12579181 (DbSNP) |
| 12 | 55,492,705 | 55,492,705 | NS | T/A | F/I | 1000GP (CEU, CHBJPT) |
| 12 | 55,493,303 | 55,493,303 | NS | G/T | R/L | 1000GP (CEU, CHBJPT) |
| 12 | 55,492,412 | 55,492,412 | NS | T/C | L/P | 1000GP (CEU) |
| 12 | 55,492,510 | 55,492,510 | NS | G/A | A/T | 1000GP (CEU, CHBJPT) |
| 12 | 55,492,595 | 55,492,595 | NS | C/T | A/V | 1000GP (CHBJPT) |
| 12 | 100 | -100 | NS | G/A | A/T | 1000GP (YRI, YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 12 | 55,832,210 | 56,001,052 | CopyNumber | Variation_4780 (DGV) |
| CopyNumber | 17 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| L17P | A50T | A78V | F115I | C192R | A303G | A312P | R314L | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | L | A | A | F | C | A | A | R | 34.87 | 1.000 |
| 2 | L | T | A | F | C | A | A | R | 27.19 | 1.000 |
| 3 | L | T | A | I | C | A | A | L | 24.81 | 1.000 |
| 4 | L | T | A | F | C | G | A | L | 5.61 | 1.000 |
| 5 | L | T | A | F | C | A | A | L | 2.92 | 1.000 |
| 6 | L | A | V | F | C | A | A | L | 2.15 | 1.000 |
| 7 | L | A | A | F | C | A | A | L | 1.08 | 1.000 |
| 8 | P | T | A | F | C | A | A | R | 0.61 | 1.000 |
| 9 | L | A | A | F | R | A | A | R | 0.31 | 1.000 |
| 10 | L | A | A | F | C | A | P | L | 0.23 | 1.000 |
| 11 | L | A | A | F | C | G | A | L | 0.15 | 1.000 |
| 12 | L | T | A | I | C | A | A | R | 0.08 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR6C68.aApr07-unspliced | main_exon | 5UTR | chr12 | 55,491,967 | 55,492,363 | + |
| CDS | chr12 | 55,492,363 | 55,493,313 | + | ||
| 3UTR | chr12 | 55,493,313 | 55,493,316 | + | ||