OR6C75 Olfactory Receptor
| Gene Symbol | OR6C751 (View this gene in GeneCards) |
| Family | 6 |
| Subfamily | C |
| Pseudogene | No |
| CORP pseudogene probability score | 0.07 (functional) |
| Aliases | HsOR12.5.14 |
| External Ids | HGNC: 31304 GeneBank: NM_001005497 |
| Build #39 labels | |
| Chromosomal location | 12:55,365,111-55,366,046 (+) |
| Cluster | 12@56 |
| Synteny | CLIC#31 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR6C3 | 71.94% | 310 |
| OR6C66P | 73.77% | 305 |
| OR6C74 | 72.99% | 311 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR6C75C | 83% | 312 |
| Dog | OR6C75D | 83% | 312 |
| Mouse | Or6c75 | 88% | 309 |
| Rat | Or6c75-ps | 85% | 312 |
| Cow | OR6C1 | 74% | 309 |
| Orang | OR6C74 | 74% | 312 |
| Horse | OR6C333P | 75% | 312 |
| Chimp | OR6C74 | 73% | 312 |
Sequence information
| Nucleotide sequence |
ATGAGAAATTCCACAGCAGTAACAGACTTTATTCTTCTTGGATTGACAAGTGACCCACAG TGGCAGGTTGTACTTTTCATATTTCTTCTTGTTACCTACATGTTAAGTGTGACTGGGAAC CTGATCATTATCACCCTCACCCTTTCAGATCCCCATCTGCAGACTCCCATGTATTTCTTC CTTCGGAACTTCTCATTCCTGGAAATTTCATTCACGTCTGTCTGCATTCCCAGATTCCTT GTCACTGTTGTGACAGGAAACAGAACCATTTCTTATAATGGGTGTGTGGCTCAGCTATTT TTTTTCATCTTCTTGGGGGTGACAGAATTTTACCTTCTGGCTGCCATGTCCTATGACCGC TGCATGGCCATCTGCAAACCTCTTCATTACACAATCATCATGAGCACCAGAGTGTGTACC CTTCTTGTCTTTAGCTCCTGGCTTGCAGGGTTTCTGATCATCTTTCCACCAGTAATGCTT CTGCTGCAGTTGGATTTCTGTGCCTCCAATGTAATTGATCATTTTATCTGTGACTCTTCT CCAATGCTGCAGCTCTCTTGCACAAACACTCACTTTCTAGAACTCATGGCATTTTTTTTA GCTGTGGTAACACTGATGGTCACCTTGACATTAGTTATTCTCTCCTACACAAACATCATC CGGACAATTCTGAAAATTCCTTCTATGAGTCAAAGGAAAAAAGCCTTTTCCACTTGCTCC TCCCATATGATAGTTGTCTCCATCTCTTACAGTAGCTGTATCTTCATGTACATTAAGACT TCTGCCAGAGAAAGGGTGACTTTAAGCAAAGGAGTAGCTGTGCTCAATACCTCAGTGGCT CCTCTCTTGAATCCCTTCATATACACACTGAGAAATAAGCAAGTGAAGCAAGCCTTCAAG AGCATGGTCCAGAAGATGATTTTTTCTTTAAATAAA |
| Conceptual translation |
MRNSTAVTDFILLGLTSDPQWQVVLFIFLLVTYMLSVTGNLIIITLTLSDPHLQTPMYFF LRNFSFLEISFTSVCIPRFLVTVVTGNRTISYNGCVAQLFFFIFLGVTEFYLLAAMSYDR CMAICKPLHYTIIMSTRVCTLLVFSSWLAGFLIIFPPVMLLLQLDFCASNVIDHFICDSS PMLQLSCTNTHFLELMAFFLAVVTLMVTLTLVILSYTNIIRTILKIPSMSQRKKAFSTCS SHMIVVSISYSSCIFMYIKTSARERVTLSKGVAVLNTSVAPLLNPFIYTLRNKQVKQAFK SMVQKMIFSLNK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 12 | 55,759,000 | 55,759,000 | NS | A/C | S/R | rs72482251 (DbSNP) |
| 12 | 55,759,315 | 55,759,315 | NS | C/T | L/F | rs7976023 (DbSNP) |
| 12 | 55,759,598 | 55,759,598 | NS | A/C | D/A | rs7976416 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 108 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| L141F | I176V | A235D | C253S | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | L | I | A | C | 98.80 | 0.087 |
| 2 | F | I | D | C | 0.55 | 0.215 |
| 3 | F | I | A | C | 0.33 | 0.087 |
| 4 | L | V | A | C | 0.22 | 0.087 |
| 5 | L | I | A | S | 0.11 | 0.087 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR6C75.aApr07-unspliced | main_exon | CDS | chr12 | 55,365,111 | 55,366,046 | + |
| 3UTR | chr12 | 55,366,046 | 55,366,049 | + | ||