OR6J1 Olfactory Receptor

Gene Symbol	OR6J1¹ (View this gene in GeneCards)
Family	6
Subfamily	J
Pseudogene	No
CORP pseudogene probability score
Aliases	HsOR14.3.1
External Ids	HGNC: 14707 GeneBank: AB065892
Build #39 labels	OR6J2, OR6J1P
Chromosomal location	14:22,633,771-22,634,811 (-)
Cluster	14@23
Synteny	CLIC#36
Remarks	Segregating Pseudo Gene, a nonsynonymous SNP in a highly conserved amino-acid (rs3751484)

Most Similar ORs in Humans (Paralogs)

Symbol	Percent	Length
OR6M1	54.78%	314
OR6M2P	52.44%	307
OR6R1P	52.49%	301

Most Similar ORs in other species (Orthologs)

Specie	Symbol	Percent	Length
Dog	OR6M1	57%	314
Mouse	Or6s1	51%	307
Rat	Or6s1	51%	316
Cow	OR6J1P	83%	292
Orang	OR6M1P	53%	312
Horse	OR6J1P	82%	311
Chimp	OR6M1	55%	314

Expression evidences

Source	Accession
ESTs	BF363816
GNF Atlas2	gnf1h02814_at

Sequence information

Nucleotide sequence

ATGGGTAACTGGACTGCAGCGGTGACTGAGTTTGTTCTGCTGGGGTTTTCCCTGAGCAGG
GAGGTGGAGCTGCTGCTCCTGGTGCTCCTGCTGCCCACGTTCCTGCTGACTCTTCTGGGG
AACCTGCTCATCATCTCCACTGTGCTGTCCTGCTCCCGCCTCCACACCCCCATGTACTTC
TTCTTGTGCAACCTCTCTATCCTGGACATCCTCTTCACCTCAGTCATCTCTCCAAAAGTG
TTGGCCAACTTAGGATCTAGGGATAAAACCATCTCCTTTGCCGGATGTATCACCCAGTGC
TATTTCTACTTTTTCTTGGGCACAGTTGAGTTCCTCCTGCTGACGGTCATGTCCTATGAC
CGTTATGCCACCATCTGCTGCCCCCTGCGGTACACCACCATCATGAGACCTTCTGTCTGC
ATTGGGACCGTTGTATTCTCTTGGGTGGGAGGCTTCCTGTCTGTGCTCTTTCCAACCATC
CTCATCTCCCAGCTGCCCTTCTGTGGCTCCAATATCATTAACCACTTCTTCTGTGACAGT
GGACCCTTGCTGGCCCTGGCCTGTGCAGACACCACTGCCATCGAGCTGATGGATTTTATG
CTTTCTTCCATGGTCATCCTCTGCTGCATAGTCCTCGTGGCCTATTCCTATACGTACATC
ATCTTGACCATAGTGCGCATTCCTTCTGCAAGTGGAAGGAAGAAGGCCTTTAATACCTGT
GCTTCCCACCTGACCATAGTCATCATTCCTAGTGGCATCACTGTGTTTATCTATGTGACT
CCCTCCCAGAAAGAATATCTGGAGATCAACAAGATCCCTTTGGTTCTGAGCAGTGTGGTG
ACTCCATTCCTCAACCCCTTTATATATACTCTGAGGAATGACACAGTGCAGGGAGTCCTC
AGGGATGTGTGGGTCAGGGTTCGAGGAGTTTTTGAAAAGAGGATGAGGGCAGTGCTGAGA
AGCAGATTATCCTCCAACAAAGACCACCAAGGAAGGGCTTGCTCTTCTCCACCATGTGTC
TATTCTGTAAAGCTCCAGTGT

Conceptual translation

MGNWTAAVTEFVLLGFSLSREVELLLLVLLLPTFLLTLLGNLLIISTVLSCSRLHTPMYF
FLCNLSILDILFTSVISPKVLANLGSRDKTISFAGCITQCYFYFFLGTVEFLLLTVMSYD
RYATICCPLRYTTIMRPSVCIGTVVFSWVGGFLSVLFPTILISQLPFCGSNIINHFFCDS
GPLLALACADTTAIELMDFMLSSMVILCCIVLVAYSYTYIILTIVRIPSASGRKKAFNTC
ASHLTIVIIPSGITVFIYVTPSQKEYLEINKIPLVLSSVVTPFLNPFIYTLRNDTVQGVL
RDVWVRVRGVFEKRMRAVLRSRLSSNKDHQGRACSSPPCVYSVKLQC

Protein domains and features

Variations - SNPs

Chr	Start	End	Type	Variation	AA Change	SNP IDs
14	100	-100	NS	G/A	S/F	1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI)
14	100	-100	SYN	A/G	F/F	1000GP (YRI, YRI, YRI, YRI)
14	22,633,879	22,633,879	SYN	A/G	F/F	1000GP (CEU, CHBJPT)
14	22,633,977	22,633,977	NS	C/A	V/L	1000GP (CEU, CHBJPT)
14	22,633,991	22,633,991	NS	A/G	L/S	1000GP (CEU, CHBJPT)
14	22,634,064	22,634,064	NS	G/A	P/S	1000GP (CEU, CHBJPT)
14	22,634,135	22,634,135	NS	C/T	R/H	1000GP (CEU, CHBJPT)
14	22,634,139	22,634,139	NS	C/T	V/M	1000GP (CEU)
14	22,634,318	22,634,318	NS	A/G	L/P	1000GP (CEU)
14	22,634,377	22,634,377	SYN	T/C	V/V	1000GP (CEU, CHBJPT)
14	22,634,399	22,634,399	NS	G/T	S/Y	1000GP (CEU)
14	22,634,442	22,634,442	NS	T/C	T/A	1000GP (CEU, CHBJPT)
14	22,634,449	22,634,449	SYN	A/G	R/R	1000GP (CEU, CHBJPT)
14	22,634,450	22,634,450	NS	C/T	R/H	1000GP (CEU, CHBJPT)
14	22,634,451	22,634,451	NS	G/A	R/C	1000GP (CEU)
14	22,634,639	22,634,639	NS	A/G	M/T	1000GP (CEU)
14	23,102,784	23,102,784	SYN	A/G	F/F	rs1753429 (DbSNP)
14	23,102,882	23,102,882	NS	A/C	L/V	rs1681596 (DbSNP)
14	23,102,896	23,102,896	NS	A/G	L/S	rs1681597 (DbSNP)
14	23,102,969	23,102,969	NS	A/G	S/P	rs1753430 (DbSNP)
14	23,103,040	23,103,040	NS	C/T	R/H	rs3829405 (DbSNP)
14	23,103,044	23,103,044	NS	C/T	V/M	rs1681598 (DbSNP)
14	23,103,282	23,103,282	SYN	C/T	V/V	rs3751481 (DbSNP)
14	23,103,304	23,103,304	NS	G/T	S/Y	rs45470397 (DbSNP)
14	23,103,347	23,103,347	NS	C/T	A/T	rs3751482 (DbSNP)
14	23,103,354	23,103,354	SYN	A/G	R/R	rs3751483 (DbSNP)
14	23,103,355	23,103,355	NS	C/T	R/H	rs3751484 (DbSNP)
14	23,103,356	23,103,356	NS	A/G	C/R	rs45494902 (DbSNP)
14	23,103,373	23,103,373	NS	G/T	T/K	rs45479894 (DbSNP)

Variations - CNVs

Chr	Start	End	Type	Sources
14	23,090,983	23,111,555	CopyNumber	Variation_35239 (DGV)

Haplotypes

Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.

	S335F	R314W	V279L	L274S	P250S	R226H	V225M	T218M	G169R	L165P	S138Y	R130W	T124A	R121H	R121C	T115K	M58T	R53H	S17P	A7V	% Freq	CORP
1	S	R	V	L	P	R	V	T	G	L	S	R	T	R	R	T	M	R	S	A	42.47	1.000
2	S	R	V	L	S	R	V	T	G	L	S	R	T	R	R	T	M	R	S	A	31.57	1.000
3	S	R	L	S	S	H	V	T	G	L	S	R	A	H	R	T	M	R	S	A	14.44	0.088
4	S	R	V	L	S	R	V	T	G	L	S	R	T	R	R	T	T	R	S	A	2.15	1.000
5	S	R	L	S	S	H	V	T	G	L	S	R	T	R	R	T	M	R	S	A	2.07	1.000
6	S	R	L	S	S	R	M	T	G	L	Y	R	A	R	C	T	M	R	S	A	1.92	0.632
7	S	R	L	S	S	H	V	T	G	L	S	R	A	H	R	T	M	R	P	A	1.08	0.088
8	S	R	L	S	S	H	V	T	G	L	S	R	A	R	R	T	M	R	S	A	0.84	0.088
9	S	R	V	L	P	R	V	T	G	L	S	R	T	R	R	K	M	R	S	A	0.69	1.000
10	S	R	L	S	S	H	V	T	G	P	S	R	A	H	R	T	M	R	S	A	0.38	0.088
11	S	R	V	L	S	R	V	T	G	L	S	R	T	R	R	T	M	H	S	A	0.23	1.000
12	S	R	L	S	S	R	M	T	G	L	Y	R	A	H	R	T	M	R	S	A	0.23	0.088
13	S	R	V	L	P	R	V	T	G	L	S	R	T	R	R	T	M	R	S	V	0.23	1.000
14	S	R	V	L	S	H	V	T	G	L	S	R	A	H	R	T	M	R	S	A	0.15	0.088
15	F	R	V	L	P	R	V	T	G	L	S	R	T	R	R	T	M	R	S	A	0.15	1.000
16	S	R	V	L	S	H	V	T	G	L	S	R	T	R	R	T	M	R	S	A	0.15	1.000
17	S	R	L	S	S	H	V	T	G	P	S	R	A	R	R	T	M	R	S	A	0.15	0.088
18	S	R	L	S	S	H	V	T	G	P	S	R	T	R	R	T	M	R	S	A	0.15	1.000
19	S	R	V	L	S	H	V	T	G	P	S	R	A	H	R	T	M	R	S	A	0.08	0.088
20	S	R	V	L	S	R	V	M	G	L	S	R	T	R	R	T	M	R	S	A	0.08	1.000
21	S	R	L	S	S	R	M	T	G	L	S	R	T	R	R	T	M	R	S	A	0.08	1.000
22	S	W	V	L	S	R	V	T	G	L	S	R	T	R	R	T	M	R	S	A	0.08	1.000
23	S	R	V	S	S	H	V	T	G	P	S	R	A	H	R	T	M	R	S	A	0.08	0.088
24	S	R	L	S	S	R	V	T	G	L	S	R	A	H	R	T	M	R	S	A	0.08	0.088
25	S	R	V	L	P	R	V	T	R	L	S	R	T	R	R	T	M	R	S	A	0.08	1.000
26	S	R	L	L	S	H	V	T	G	L	S	R	A	H	R	T	M	R	S	A	0.08	0.088
27	S	R	V	L	P	R	V	T	G	L	S	R	T	R	R	T	M	H	S	A	0.08	1.000
28	S	R	L	S	S	H	V	T	G	L	S	R	A	R	R	T	M	R	P	A	0.08	0.088
29	S	R	V	L	P	H	V	T	G	L	S	R	T	R	R	T	M	R	S	A	0.08	1.000
30	S	R	V	L	S	R	V	T	G	L	S	W	T	R	R	T	M	R	S	A	0.08	1.000

HORDE

Search Olfactory receptors

Select ORs from