OR6K6 Olfactory Receptor
| Gene Symbol | OR6K61 (View this gene in GeneCards) |
| Family | 6 |
| Subfamily | K |
| Pseudogene | No |
| CORP pseudogene probability score | 1 (pseudogene) |
| Aliases | OR1-21, HsOR1.4.16, ORL3010 |
| External Ids | HGNC: 15033 GeneBank: AB065650, BK004198, NM_001005184 ORDB: ORL3010 |
| Build #39 labels | OR6K6 |
| Chromosomal location | 1:158,754,921-158,755,844 (+) |
| Cluster | 1@159a |
| Synteny | CLIC#4 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR6K4P | 70.55% | 292 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR6K8 | 66% | 313 |
| Mouse | Or6k6 | 83% | 319 |
| Rat | Or6k6 | 82% | 319 |
| Cow | OR6K4 | 67% | 309 |
| Orang | OR6K4B | 69% | 305 |
| Horse | OR6K4 | 67% | 304 |
| Chimp | OR6K4 | 70% | 305 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC140743 |
| GNF Atlas2 | gnf1h10921_at |
Sequence information
| Nucleotide sequence |
ATGGTGACTGAGTTCCTCTTCTCTATGTTCCCGCATGCGCACAGAGGTGGCCTCTTATTC TTTATTCCCTTGCTTCTCATCTACGGATTTATCCTAACTGGAAACCTAATAATGTTCATT GTCATCCAGGTGGGCATGGCCCTGCACACCCCTTTGTATTTCTTTATCAGTGTCCTCTCC TTCCTGGAGATCTGCTATACCACAACCACCATCCCCAAGATGCTGTCCTGCCTAATCAGT GAGCAGAAGAGCATTTCCGTGGCTGGCTGCCTCCTGCAGATGTACTTTTTCCACTCACTT GGTATCACAGAAAGCTGTGTCCTGACAGCAATGGCCATTGACAGGTACATAGCTATCTGC AATCCACTCCGTTACCCAACCATCATGATTCCCAAACTTTGTATCCAGCTGACAGTTGGA TCCTGCTTTTGTGGCTTCCTCCTTGTGCTTCCTGAGATTGCATGGATTTCCACCTTGCCT TTCTGTGGCTCCAACCAGATCCACCAGATATTCTGTGATTTCACACCTGTGCTGAGCTTG GCCTGCACAGATACATTCCTAGTGGTCATTGTGGATGCCATCCATGCAGCGGAAATTGTA GCCTCCTTCCTGGTCATTGCTCTATCCTACATCCGGATTATTATAGTGATTCTGGGAATG CACTCAGCTGAAGGTCATCACAAGGCCTTTTCCACCTGTGCTGCTCACCTTGCTGTGTTC TTGCTATTTTTTGGCAGTGTGGCTGTCATGTATTTGAGATTCTCAGCCACCTACTCAGTG TTTTGGGACACAGCAATTGCTGTCACTTTTGTTATCCTTGCTCCCTTTTTCAACCCCATC ATCTATAGCCTGAAAAACAAGGACATGAAAGAGGCTATTGGAAGGCTTTTCCACTATCAG AAGAGGGCTGGTTGGGCTGGGAAA |
| Conceptual translation |
MTQLTASGNQTMVTEFLFSMFPHAHRGGLLFFIPLLLIYGFILTGNLIMFIVIQVGMALH TPLYFFISVLSFLEICYTTTTIPKMLSCLISEQKSISVAGCLLQMYFFHSLGITESCVLT AMAIDRYIAICNPLRYPTIMIPKLCIQLTVGSCFCGFLLVLPEIAWISTLPFCGSNQIHQ IFCDFTPVLSLACTDTFLVVIVDAIHAAEIVASFLVIALSYIRIIIVILGMHSAEGHHKA FSTCAAHLAVFLLFFGSVAVMYLRFSATYSVFWDTAIAVTFVILAPFFNPIIYSLKNKDM KEAIGRLFHYQKRAGWAGK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 158,725,564 | 158,725,564 | NS | A/G | K/R | rs16841045 (DbSNP) |
| 1 | 158,724,844 | 158,724,844 | NS | A/G | D/G | rs16840980 (DbSNP) |
| 1 | 158,725,387 | 158,725,387 | NS | A/G | H/R | rs16841042 (DbSNP) |
| 1 | 158,725,345 | 158,725,345 | NS | A/G | Q/R | rs16841038 (DbSNP) |
| 1 | 158,724,988 | 158,724,988 | NS | A/G | Q/R | rs74122455 (DbSNP) |
| 1 | 158,724,722 | 158,724,722 | NS | C/G | D/E | rs16840974 (DbSNP) |
| 1 | 158,725,006 | 158,725,006 | NS | C/T | S/L | rs16840991 (DbSNP) |
| 1 | 158,725,080 | 158,725,080 | NS | C/T | R/C | rs16841001 (DbSNP) |
| 1 | 158,725,194 | 158,725,194 | NS | C/T | R/C | rs16841009 (DbSNP) |
| 1 | 158,724,750 | 158,724,750 | NS | C/T | H/Y | rs16840976 (DbSNP) |
| 1 | 158,725,237 | 158,725,237 | NS | C/T | P/L | rs16841017 (DbSNP) |
| 1 | 158,725,301 | 158,725,301 | SYN | A/G | A/A | rs16841025 (DbSNP) |
| 1 | 158,725,310 | 158,725,310 | SYN | A/T | V/V | rs16841033 (DbSNP) |
| 1 | 158,724,794 | 158,724,794 | SYN | C/T | Y/Y | rs57046052 (DbSNP) |
| 1 | 158,725,100 | 158,725,100 | SYN | C/T | I/I | rs7540544 (DbSNP) |
| 1 | 158,724,965 | 158,724,965 | SYN | C/T | I/I | rs16840986 (DbSNP) |
| 1 | 158,725,269 | 158,725,269 | SYN | C/T | L/L | rs74122456 (DbSNP) |
| 1 | 158,755,290 | 158,755,290 | NS | C/T | R/C | 1000GP (CEU, CHBJPT) |
| 1 | 158,755,021 | 158,755,021 | NS | G/A | G/E | 1000GP (CEU) |
| 1 | 158,755,359 | 158,755,359 | NS | C/T | L/F | 1000GP (CEU) |
| 1 | 100 | -100 | NS | G/C | E/D | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | T/C | I/I | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 158,725,318 | 158,726,269 | InDel | Variation_97523 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| E15D | H25Y | G45E | G56D | Q104R | S110L | R135C | C173R | P187L | R223Q | I224N | H237R | A276V | K296R | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | E | H | G | G | Q | S | R | C | P | R | I | H | A | K | 80.95 | 0.558 |
| 2 | E | H | G | G | Q | S | C | C | P | R | I | H | A | K | 10.91 | 0.558 |
| 3 | E | Y | G | D | R | L | R | R | L | Q | I | R | A | R | 3.76 | 0.914 |
| 4 | D | Y | G | D | R | L | R | R | L | Q | I | H | A | R | 3.46 | 0.898 |
| 5 | E | H | E | G | Q | S | C | C | P | R | I | H | A | K | 0.31 | 0.558 |
| 6 | E | Y | G | D | R | L | R | C | P | R | I | H | A | K | 0.08 | 0.898 |
| 7 | D | Y | G | D | R | L | R | R | L | Q | I | R | A | R | 0.08 | 0.914 |
| 8 | E | Y | G | D | R | L | R | R | L | Q | I | H | A | R | 0.08 | 0.898 |
| 9 | D | Y | G | D | Q | S | R | C | P | R | I | H | A | K | 0.08 | 0.558 |
| 10 | D | Y | G | G | Q | S | R | C | P | R | I | H | A | K | 0.08 | 0.558 |
| 11 | E | H | G | G | Q | S | R | C | P | R | N | H | A | K | 0.08 | 0.558 |
| 12 | D | H | G | D | Q | S | R | R | P | R | I | H | A | K | 0.08 | 0.558 |
| 13 | E | H | G | G | Q | S | R | C | P | R | I | H | V | K | 0.08 | 0.558 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR6K6.aApr07-unspliced | main_exon | 5UTR | chr1 | 158,754,816 | 158,754,921 | + |
| CDS | chr1 | 158,754,921 | 158,755,844 | + | ||
| 3UTR | chr1 | 158,755,844 | 158,755,847 | + | ||