OR6P1 Olfactory Receptor
| Gene Symbol | OR6P11 (View this gene in GeneCards) |
| Family | 6 |
| Subfamily | P |
| Pseudogene | No |
| CORP pseudogene probability score | 0.05 (functional) |
| Aliases | OR1-12, HsOR1.4.8, ORL3014 |
| External Ids | HGNC: 15036 GeneBank: AB065637, AF399473, BK004193, NG_004287 ORDB: ORL3014 |
| Build #39 labels | OR6P1 |
| Chromosomal location | 1:158,562,654-158,563,604 (-) |
| Cluster | 1@159a |
| Synteny | CLIC#4 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR6A2 | 58.72% | 298 |
| OR6B1 | 57.63% | 295 |
| OR6Y1 | 59.6% | 302 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR6A2 | 58% | 303 |
| Mouse | Or6p1 | 90% | 317 |
| Rat | Or6p1 | 88% | 317 |
| Cow | OR6A2 | 59% | 308 |
| Orang | OR6P2 | 99% | 200 |
| Horse | OR6B13 | 61% | 297 |
| Chimp | OR6Y1 | 59% | 303 |
Expression evidences
| Source | Accession |
|---|---|
| GNF Atlas2 | gnf1h01973_at |
| GNF Atlas2 | gnf1h01974_s_at |
Sequence information
| Nucleotide sequence |
ATGAGAAATTTGAGTGGAGGCCATGTCGAGGAGTTTGTCTTGGTGGGTTTCCCTACCACG CCTCCCCTCCAGCTGCTCCTCTTTGTCCTTTTTTTTGCAATTTACCTTCTGACATTGTTG GAGAATGCACTTATTGTCTTCACAATATGGCTTGCTCCAAGCCTTCATCGTCCCATGTAC TTTTTCCTTGGCCATCTCTCTTTCCTGGAGCTATGGTACATCAATGTCACCATTCCTCGG CTCTTGGCAGCCTTTCTTACCCAGGATGGTAGAGTCTCCTACGTAGGTTGCATGACCCAA CTGTACTTCTTTATTGCCTTAGCCTGTACTGAATGTGTGCTGTTGGCAGTTATGGCCTAT GATCGCTACCTGGCCATCTGTGGACCCCTCCTTTACCCTAGTCTCATGCCTTCCAGTCTG GCCACTCGCCTTGCTGCTGCCTCTTGGGGCAGTGGCTTCTTCAGCTCCATGATGAAGCTT CTTTTTATTTCCCAATTGTCCTACTGTGGACCCAACATTATCAACCACTTTTTCTGTGAT ATTTCCCCACTACTCAACCTCACCTGCTCTGACAAGGAGCAAGCAGAGCTAGTAGACTTC CTTCTGGCCCTGGTGATGATTCTACTCCCTCTATTGGCTGTGGTTTCATCATACACTGCC ATCATTGCAGCCATCCTGAGGATCCCTACGTCCAGGGGACGCCACAAAGCCTTTTCCACT TGTGCCGCTCATCTGGCAGTGGTTGTTATCTACTACTCCTCCACTCTCTTCACCTATGCA CGGCCCCGGGCCATGTACACCTTCAACCACAACAAGATTATCTCTGTGCTCTACACTATC ATTGTACCATTCTTCAACCCAGCCATCTACTGCCTGAGGAACAAGGAGGTGAAGGAGGCC TTCAGGAAGACAGTGATGGGCAGATGTCACTATCCTAGGGATGTTCAGGAC |
| Conceptual translation |
MRNLSGGHVEEFVLVGFPTTPPLQLLLFVLFFAIYLLTLLENALIVFTIWLAPSLHRPMY FFLGHLSFLELWYINVTIPRLLAAFLTQDGRVSYVGCMTQLYFFIALACTECVLLAVMAY DRYLAICGPLLYPSLMPSSLATRLAAASWGSGFFSSMMKLLFISQLSYCGPNIINHFFCD ISPLLNLTCSDKEQAELVDFLLALVMILLPLLAVVSSYTAIIAAILRIPTSRGRHKAFST CAAHLAVVVIYYSSTLFTYARPRAMYTFNHNKIISVLYTIIVPFFNPAIYCLRNKEVKEA FRKTVMGRCHYPRDVQD Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | C/A | A/S | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | G/A | I/I | 1000GP (YRI, YRI, YRI, YRI) |
| 1 | 158,532,460 | 158,532,460 | NS | A/G | L/P | rs41273495 (DbSNP) |
| 1 | 158,532,607 | 158,532,607 | NS | C/T | R/Q | rs41273497 (DbSNP) |
| 1 | 158,532,614 | 158,532,614 | NS | A/G | W/R | rs41273499 (DbSNP) |
| 1 | 158,533,006 | 158,533,005 | Ins(1) | -/G | rs34323808 (DbSNP) | |
| 1 | 158,533,017 | 158,533,017 | SYN | A/G | I/I | rs10489837 (DbSNP) |
| 1 | 158,533,095 | 158,533,095 | SYN | C/T | Q/Q | rs73014246 (DbSNP) |
| 1 | 158,533,140 | 158,533,140 | SYN | A/G | F/F | rs12080815 (DbSNP) |
| 1 | 158,533,171 | 158,533,171 | NS | C/T | S/N | rs41273501 (DbSNP) |
| 1 | 158,533,224 | 158,533,224 | SYN | A/G | R/R | rs12081915 (DbSNP) |
| 1 | 158,562,657 | 158,562,657 | NS | C/A | Q/H | 1000GP (CEU) |
| 1 | 158,562,670 | 158,562,670 | NS | G/A | P/L | 1000GP (CEU) |
| 1 | 158,562,824 | 158,562,824 | NS | G/A | R/W | 1000GP (CEU) |
| 1 | 158,563,350 | 158,563,350 | SYN | A/G | F/F | 1000GP (CEU, CHBJPT) |
| 1 | 158,563,381 | 158,563,381 | NS | T/C | N/S | 1000GP (CEU) |
| 1 | 158,563,434 | 158,563,434 | SYN | A/G | R/R | 1000GP (CEU, CHBJPT) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 158,530,444 | 158,533,494 | Deletion | #178 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| R313K | P312L | A264S | R261W | R234H | A223V | L185F | I163V | M157K | N75S | M59R | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | R | P | A | R | R | A | L | I | M | N | M | 92.24 | 0.179 |
| 2 | R | P | A | W | R | A | L | I | M | N | M | 3.46 | 0.179 |
| 3 | R | P | A | R | H | A | L | I | M | N | M | 1.61 | 0.153 |
| 4 | R | P | S | R | R | A | L | V | M | N | R | 0.69 | 0.646 |
| 5 | R | P | A | R | R | V | L | I | M | N | M | 0.54 | 0.179 |
| 6 | R | L | A | R | R | A | L | I | M | N | M | 0.46 | 0.179 |
| 7 | R | P | A | R | R | A | F | I | M | N | M | 0.46 | 0.179 |
| 8 | R | P | S | R | R | A | L | V | K | N | R | 0.31 | 0.646 |
| 9 | K | P | A | R | R | A | L | I | M | N | M | 0.15 | 0.179 |
| 10 | R | P | A | R | R | A | L | I | M | S | M | 0.08 | 0.179 |