OR6Y1 Olfactory Receptor
| Gene Symbol | OR6Y11 (View this gene in GeneCards) |
| Family | 6 |
| Subfamily | Y |
| Pseudogene | No |
| CORP pseudogene probability score | 0.05 (functional) |
| Aliases | OR1-11, HsOR1.4.7, ORL3002 |
| External Ids | HGNC: 14823 GeneBank: AB065638, BK004192, NM_001005189 ORDB: ORL3002 |
| Build #39 labels | OR6Y1, OR6Y2 |
| Chromosomal location | 1:158,547,131-158,548,105 (-) |
| Cluster | 1@159a |
| Synteny | CLIC#4 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR6A2 | 57.56% | 311 |
| OR6B1 | 54.52% | 310 |
| OR6P1 | 59.6% | 302 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR6Y1P | 90% | 301 |
| Mouse | Or6y1 | 87% | 320 |
| Rat | Or6y1 | 87% | 325 |
| Cow | OR6P1 | 60% | 304 |
| Orang | OR6P1 | 58% | 303 |
| Horse | OR6Y1P | 88% | 302 |
| Chimp | OR6A2 | 58% | 311 |
Sequence information
| Nucleotide sequence |
ATGACCACCATAATTCTGGAAGTAGATAATCATACAGTGACAACACGTTTCATTCTTCTG GGGTTTCCAACACGACCAGCCTTCCAGCTTCTCTTTTTCTCCATTTTCCTGGCAACCTAT CTGCTGACACTGCTGGAGAATCTTCTTATCATCTTAGCTATCCACAGTGATGGGCAGCTG CATAAGCCCATGTACTTCTTCTTGAGCCACCTCTCCTTCCTGGAGATGTGGTATGTCACA GTCATCAGCCCCAAGATGCTTGTTGACTTCCTCAGTCATGACAAGAGTATTTCCTTCAAT GGCTGCATGACTCAACTTTACTTTTTTGTGACCTTTGTCTGCACTGAGTACATCCTTCTT GCTATCATGGCCTTTGACCGCTATGTAGCCATTTGTAATCCACTACGCTACCCAGTCATC ATGACCAACCAGCTCTGTGGCACACTGGCTGGAGGATGCTGGTTCTGTGGACTCATGACT GCCATGATTAAGATGGTTTTTATAGCACAACTTCACTACTGTGGCATGCCTCAGATCAAT CACTACTTTTGTGATATCTCTCCACTCCTTAACGTCTCCTGTGAGGATGCCTCACAGGCT GAGATGGTGGACTTCTTCTTGGCCCTCATGGTCATTGCTATTCCTCTTTGTGTTGTGGTG GCATCCTACGCTGCTATCCTTGCCACCATCCTCAGGATCCCTTCTGCTCAGGGCCGCCAA AAGGCATTCTCCACCTGTGCCTCCCACCTGACCGTCGTAATTCTCTTCTATTCCATGACA CTTTTCACCTATGCCCGTCCCAAACTCATGTATGCCTACAATTCCAACAAAGTGGTATCT GTTCTCTACACTGTCATTGTTCCACTCCTCAACCCCATCATTTACTGTCTGAGGAACCAT GAAGTAAAGGCAGCCCTCAGAAAGACCATACATTGCAGAGGAAGTGGGCCCCAGGGAAAT GGGGCTTTCAGTAGT |
| Conceptual translation |
MTTIILEVDNHTVTTRFILLGFPTRPAFQLLFFSIFLATYLLTLLENLLIILAIHSDGQL HKPMYFFLSHLSFLEMWYVTVISPKMLVDFLSHDKSISFNGCMTQLYFFVTFVCTEYILL AIMAFDRYVAICNPLRYPVIMTNQLCGTLAGGCWFCGLMTAMIKMVFIAQLHYCGMPQIN HYFCDISPLLNVSCEDASQAEMVDFFLALMVIAIPLCVVVASYAAILATILRIPSAQGRQ KAFSTCASHLTVVILFYSMTLFTYARPKLMYAYNSNKVVSVLYTVIVPLLNPIIYCLRNH EVKAALRKTIHCRGSGPQGNGAFSS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | C/A | R/L | 1000GP (YRI, YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | G/A | V/V | 1000GP (YRI, YRI, YRI, YRI) |
| 1 | 158,517,041 | 158,517,041 | SYN | A/G | V/V | rs73014208 (DbSNP) |
| 1 | 158,517,142 | 158,517,142 | NS | C/T | V/I | rs41273491 (DbSNP) |
| 1 | 158,517,353 | 158,517,353 | SYN | A/G | H/H | rs16840314 (DbSNP) |
| 1 | 158,517,489 | 158,517,489 | NS | C/T | R/H | rs41273493 (DbSNP) |
| 1 | 158,517,585 | 158,517,585 | NS | A/G | I/T | rs55665765 (DbSNP) |
| 1 | 158,517,816 | 158,517,816 | NS | C/G | G/A | rs61820493 (DbSNP) |
| 1 | 158,517,879 | 158,517,878 | Ins(1) | -/C | rs35572510 (DbSNP) | |
| 1 | 158,547,352 | 158,547,352 | NS | C/T | V/I | 1000GP (CEU, CHBJPT) |
| 1 | 158,547,563 | 158,547,563 | SYN | G/A | H/H | 1000GP (CEU, CHBJPT) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 158,514,921 | 158,517,995 | Deletion | #263 (Waszak) |
| 1 | 158,516,200 | 158,521,770 | CopyNumber | Variation_84604 (DGV) |
| 1 | 158,516,996 | 158,520,417 | CopyNumber | Variation_38148 (DGV) |
| 1 | 158,517,353 | 158,521,392 | CopyNumber | Variation_48145 (DGV), Variation_53317 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| R266L | V252I | C174R | T142I | I118N | F109L | T104I | F90C | V13M | T2I | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | R | V | C | T | I | F | T | F | V | T | 71.35 | 0.140 |
| 2 | R | I | C | T | I | F | T | F | V | T | 20.97 | 0.172 |
| 3 | R | V | C | T | I | F | I | F | V | T | 2.38 | 0.140 |
| 4 | R | V | C | T | I | F | T | F | V | I | 2.23 | 0.140 |
| 5 | L | V | C | T | I | F | T | F | V | T | 1.69 | 0.140 |
| 6 | R | V | C | I | I | F | T | F | V | T | 0.77 | 0.140 |
| 7 | R | I | C | T | N | F | T | F | V | T | 0.23 | 0.172 |
| 8 | R | V | R | T | I | F | T | F | V | T | 0.15 | 0.140 |
| 9 | R | V | C | T | I | L | T | F | V | T | 0.08 | 0.140 |
| 10 | R | V | C | T | I | F | T | C | V | T | 0.08 | 0.140 |
| 11 | R | V | C | T | I | F | T | F | M | T | 0.08 | 0.140 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR6Y1.aApr07-unspliced | main_exon | 3UTR | chr1 | 158,547,128 | 158,547,131 | - |
| CDS | chr1 | 158,547,131 | 158,548,105 | - | ||