OR6V1 Olfactory Receptor
| Gene Symbol | OR6V11 (View this gene in GeneCards) |
| Family | 6 |
| Subfamily | V |
| Pseudogene | No |
| CORP pseudogene probability score | 0.07 (functional) |
| Aliases | OR7-3, HsOR7.6.2, ORL3172 |
| External Ids | HGNC: 15090 GeneBank: AB065697, AB065873, BK004392, NM_001001667 ORDB: ORL3172 |
| Build #39 labels | OR6V1 |
| Chromosomal location | 7:143,052,341-143,053,279 (+) |
| Cluster | 7@143a |
| Synteny | CLIC#15 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR6W1P | 52.88% | 295 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR6W1 | 54% | 307 |
| Mouse | Or6s1 | 47% | 300 |
| Rat | Or6e1 | 47% | 304 |
| Cow | OR6V1P | 84% | 312 |
| Orang | OR6V1P | 95% | 305 |
| Horse | OR6V1P | 85% | 312 |
| Chimp | OR6W1P | 53% | 306 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC137044 |
| GNF Atlas2 | gnf1h10925_at |
Sequence information
| Nucleotide sequence |
ATGGCAAATCTGAGCCAGCCCTCCGAATTTGTCCTCTTGGGCTTCTCCTCCTTTGGTGAG CTGCAGGCCCTTCTGTATGGCCCCTTCCTCATGCTTTATCTTCTCGCCTTCATGGGAAAC ACCATCATCATAGTTATGGTCATAGCTGACACCCACCTACATACACCCATGTACTTCTTC CTGGGCAATTTTTCCCTGCTGGAGATCTTGGTAACCATGACTGCAGTGCCCAGGATGCTC TCAGACCTGTTGGTCCCCCACAAAGTCATTACCTTCACTGGCTGCATGGTCCAGTTCTAC TTCCACTTTTCCCTGGGGTCCACCTCCTTCCTCATCCTGACAGACATGGCCCTTGATCGC TTTGTGGCCATCTGCCACCCACTGCGCTATGGCACTCTGATGAGCCGGGCTATGTGTGTC CAGCTGGCTGGGGCTGCCTGGGCAGCTCCTTTCCTAGCCATGGTACCCACTGTCCTCTCC CGAGCTCATCTTGATTACTGCCATGGCGACGTCATCAACCACTTCTTCTGTGACAATGAA CCTCTCCTGCAGTTGTCATGCTCTGACACTCGCCTGTTGGAATTCTGGGACTTTCTGATG GCCTTGACCTTTGTCCTCAGCTCCTTCCTGGTGACCCTCATCTCCTATGGCTACATAGTG ACCACTGTGCTGCGGATCCCCTCTGCCAGCAGCTGCCAGAAGGCTTTCTCCACTTGCGGG TCTCACCTCACACTGGTCTTCATCGGCTACAGTAGTACCATCTTTCTGTATGTCAGGCCT GGCAAAGCTCACTCTGTGCAAGTCAGGAAGGTCGTGGCCTTGGTGACTTCAGTTCTCACC CCCTTTCTCAATCCCTTTATCCTTACCTTCTGCAATCAGACAGTTAAAACAGTGCTACAG GGGCAGATGCAGAGGCTGAAAGGCCTTTGCAAGGCACAA |
| Conceptual translation |
MANLSQPSEFVLLGFSSFGELQALLYGPFLMLYLLAFMGNTIIIVMVIADTHLHTPMYFF LGNFSLLEILVTMTAVPRMLSDLLVPHKVITFTGCMVQFYFHFSLGSTSFLILTDMALDR FVAICHPLRYGTLMSRAMCVQLAGAAWAAPFLAMVPTVLSRAHLDYCHGDVINHFFCDNE PLLQLSCSDTRLLEFWDFLMALTFVLSSFLVTLISYGYIVTTVLRIPSASSCQKAFSTCG SHLTLVFIGYSSTIFLYVRPGKAHSVQVRKVVALVTSVLTPFLNPFILTFCNQTVKTVLQ GQMQRLKGLCKAQ Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 7 | 100 | -100 | NS | T/C | M/T | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 7 | 100 | -100 | SYN | C/T | P/P | 1000GP (YRI, YRI, YRI, YRI) |
| 7 | 142,749,695 | 142,749,695 | SYN | C/T | P/P | rs61997195 (DbSNP) |
| 7 | 142,749,723 | 142,749,723 | NS | A/G | M/V | rs60614398 (DbSNP) |
| 7 | 142,749,737 | 142,749,737 | SYN | C/T | Y/Y | rs17164103 (DbSNP) |
| 7 | 142,749,748 | 142,749,747 | Ins(1) | -/C | rs34389632 (DbSNP) | |
| 7 | 142,749,919 | 142,749,919 | NS | A/G | Q/R | rs28563993 (DbSNP) |
| 7 | 142,749,928 | 142,749,928 | NS | C/T | P/L | rs61736210 (DbSNP) |
| 7 | 142,749,953 | 142,749,953 | SYN | C/T | I/I | rs11975892 (DbSNP) |
| 7 | 142,750,147 | 142,750,147 | NS | C/T | S/F | rs10245778 (DbSNP) |
| 7 | 142,750,243 | 142,750,243 | NS | A/G | K/R | rs7791886 (DbSNP) |
| 7 | 142,750,304 | 142,750,304 | SYN | C/T | T/T | rs4725609 (DbSNP) |
| 7 | 142,750,321 | 142,750,321 | NS | C/T | A/V | rs7779316 (DbSNP) |
| 7 | 142,750,355 | 142,750,355 | SYN | A/G | L/L | rs7792047 (DbSNP) |
| 7 | 143,052,640 | 143,052,640 | SYN | C/T | Y/Y | 1000GP (CEU, CHBJPT) |
| 7 | 143,052,822 | 143,052,822 | NS | G/A | R/Q | 1000GP (CEU) |
| 7 | 143,052,856 | 143,052,856 | SYN | C/T | I/I | 1000GP (CEU, CHBJPT) |
| 7 | 143,053,050 | 143,053,050 | NS | C/T | S/F | 1000GP (CEU) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| M1T | R129C | R161Q | L164P | S237F | R269K | V295A | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | M | R | R | L | S | R | V | 78.96 | 0.160 |
| 2 | M | R | R | L | F | R | V | 8.29 | 0.230 |
| 3 | M | R | Q | L | S | R | V | 7.22 | 0.160 |
| 4 | M | R | R | P | S | K | V | 2.23 | 0.160 |
| 5 | M | R | R | P | S | K | A | 1.84 | 0.160 |
| 6 | T | R | R | P | S | K | V | 0.84 | 1.200 |
| 7 | M | C | R | L | S | R | V | 0.15 | 0.160 |
| 8 | M | R | R | P | S | R | V | 0.15 | 0.160 |
| 9 | M | R | R | L | S | K | V | 0.15 | 0.160 |
| 10 | M | C | Q | L | S | R | V | 0.08 | 0.160 |
| 11 | T | R | R | L | S | K | V | 0.08 | 1.200 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR6V1.aApr07-unspliced | main_exon | CDS | chr7 | 143,052,341 | 143,053,279 | + |
| 3UTR | chr7 | 143,053,279 | 143,053,282 | + | ||