OR7D4 Olfactory Receptor
| Gene Symbol | OR7D41 (View this gene in GeneCards) |
| Family | 7 |
| Subfamily | D |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | hg105, OR19-B, OR19-7, HsOR19.2.11 |
| External Ids | HGNC: 8380 GeneBank: AB065929, AF399429, BK004226, NM_001005191 |
| Build #39 labels | OR7D4P |
| Chromosomal location | 19:9,213,902-9,214,837 (-) |
| Cluster | 19@9b |
| Synteny | CLIC#42 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR7D1P | 90.03% | 311 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR7D7 | 78% | 311 |
| Mouse | Or7d9 | 78% | 312 |
| Rat | Or7d9 | 76% | 312 |
| Cow | OR7D2 | 70% | 311 |
| Orang | OR4D4CP | 95% | 289 |
| Horse | OR7D4H | 82% | 311 |
| Horse | OR7D4E | 81% | 310 |
| Horse | OR7D4G | 80% | 310 |
| Chimp | OR7D4B | 94% | 311 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | CR747147 |
| mRNA | BC137162 |
| GNF Atlas2 | gnf1h09749_x_at |
Sequence information
| Nucleotide sequence |
ATGGAAGCAGAAAACCTTACAGAATTATCAAAATTTCTCCTCCTGGGACTCTCAGATGAT CCTGAACTGCAGCCCGTCCTCTTTGGGCTGTTCCTGTCCATGTACCTGGTCACGGTGCTG GGGAACCTGCTCATCATTCTGGCCGTCAGCTCTGACTCCCACCTCCACACCCCCATGTAC TTCTTCCTCTCCAACCTGTCCTTTGTTGACATCTGTTTCATCTCCACCACAGTCCCCAAG ATGCTAGTGAGCATCCAGGCACGGAGCAAAGACATCTCCTACATGGGGTGCCTCACTCAG GTGTATTTTTTAATGATGTTTGCTGGAATGGATACTTTCCTACTGGCCGTGATGGCCTAT GACCGGTTTGTGGCCATCTGCCACCCACTGCACTACACGGTCATCATGAACCCCTGCCTC TGTGGCCTCCTGGTTCTGGCATCTTGGTTCATCATTTTCTGGTTCTCCCTGGTTCATATT CTACTGATGAAGAGGTTGACCTTCTCCACAGGCACTGAGATTCCGCATTTCTTCTGTGAA CCGGCTCAGGTCCTCAAGGTGGCCTGCTCTAACACCCTCCTCAATAACATTGTCTTGTAT GTGGCCACGGCACTGCTGGGTGTGTTTCCTGTAGCTGGGATCCTCTTCTCCTACTCTCAG ATTGTCTCCTCCTTAATGGGAATGTCCTCCACCAAGGGCAAGTACAAAGCCTTTTCCACC TGTGGATCTCACCTCTGTGTGGTCTCCTTGTTCTATGGAACAGGACTTGGGGTCTATCTG AGTTCTGCTGTGACCCATTCTTCCCAGAGCAGCTCCACCGCCTCAGTGATGTACGCCATG GTCACCCCCATGCTGAACCCCTTCATCTACAGCCTGAGGAACAAGGATGTGAAGGGGGCC CTGGAAAGACTCCTCAGCAGGGCCGACTCTTGTCCA |
| Conceptual translation |
MEAENLTELSKFLLLGLSDDPELQPVLFGLFLSMYLVTVLGNLLIILAVSSDSHLHTPMY FFLSNLSFVDICFISTTVPKMLVSIQARSKDISYMGCLTQVYFLMMFAGMDTFLLAVMAY DRFVAICHPLHYTVIMNPCLCGLLVLASWFIIFWFSLVHILLMKRLTFSTGTEIPHFFCE PAQVLKVACSNTLLNNIVLYVATALLGVFPVAGILFSYSQIVSSLMGMSSTKGKYKAFST CGSHLCVVSLFYGTGLGVYLSSAVTHSSQSSSTASVMYAMVTPMLNPFIYSLRNKDVKGA LERLLSRADSCP Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 19 | 100 | -100 | NS | G/A | T/M | 1000GP (YRI, YRI) |
| 19 | 100 | -100 | SYN | G/A | A/A | 1000GP (YRI, YRI) |
| 19 | 9,214,440 | 9,214,440 | NS | G/A | T/M | 1000GP (CEU, CHBJPT) |
| 19 | 9,214,576 | 9,214,576 | NS | G/A | R/W | 1000GP (CHBJPT) |
| 19 | 9,324,590 | 9,324,590 | SYN | A/G | A/A | rs10419202 (DbSNP) |
| 19 | 9,324,640 | 9,324,640 | NS | G/T | L/M | rs4564704 (DbSNP) |
| 19 | 9,324,758 | 9,324,758 | SYN | G/A | Y/Y | rs61732676 (DbSNP) |
| 19 | 9,324,863 | 9,324,863 | SYN | A/G | S/S | rs8109935 (DbSNP) |
| 19 | 9,325,097 | 9,325,097 | SYN | A/G | C/C | rs5020274 (DbSNP) |
| 19 | 9,325,098 | 9,325,098 | NS | C/T | C/Y | rs5020275 (DbSNP) |
| 19 | 9,325,099 | 9,325,099 | NS | A/G | C/R | rs5020276 (DbSNP) |
| 19 | 9,325,106 | 9,325,106 | NS | C/T | M/I | rs5020277 (DbSNP) |
| 19 | 9,325,116 | 9,325,116 | NS | A/G | M/T | rs5020278 (DbSNP) |
| 19 | 9,325,121 | 9,325,121 | NS | C/G | Q/H | rs5020279 (DbSNP) |
| 19 | 9,325,252 | 9,325,252 | NS | G/A | R/W | rs61729907 (DbSNP) |
| 19 | 9,325,263 | 9,325,263 | NS | C/T | S/N | rs5020280 (DbSNP) |
| 19 | 9,325,278 | 9,325,278 | NS | G/A | P/L | rs61732668 (DbSNP) |
| 19 | 9,325,290 | 9,325,290 | NS | C/G | C/S | rs5020281 (DbSNP) |
| 19 | 9,325,465 | 9,325,465 | NS | A/G | F/L | rs57568862 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 115 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| K232E | G227R | T133M | R88W | S84N | P79L | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | K | G | T | R | S | P | 79.19 | 0.080 |
| 2 | K | G | M | W | S | P | 16.44 | 0.080 |
| 3 | K | G | T | R | S | L | 2.84 | 0.192 |
| 4 | K | G | T | R | N | P | 1.15 | 0.080 |
| 5 | K | R | T | R | S | P | 0.15 | 0.080 |
| 6 | E | G | T | R | S | P | 0.08 | 0.080 |
| 7 | K | G | T | W | S | L | 0.08 | 0.192 |
| 8 | K | G | M | R | S | P | 0.08 | 0.080 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR7D4.aApr07-unspliced | main_exon | 3UTR | chr19 | 9,213,899 | 9,213,902 | - |
| CDS | chr19 | 9,213,902 | 9,214,837 | - | ||