OR9K2 Olfactory Receptor
| Gene Symbol | OR9K21 (View this gene in GeneCards) |
| Family | 9 |
| Subfamily | K |
| Pseudogene | No |
| CORP pseudogene probability score | 0.02 (functional) |
| Aliases | OR12-2, HsOR12.5.2, ORL3656 |
| External Ids | HGNC: 15339 GeneBank: AB065862, BK004326, NM_001005243 ORDB: ORL3656 |
| Build #39 labels | OR9K2 |
| Chromosomal location | 12:55,129,835-55,130,773 (+) |
| Cluster | 12@56 |
| Synteny | CLIC#31 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR9K1P | 72.76% | 312 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR9K2D | 86% | 309 |
| Dog | OR9K2C | 86% | 309 |
| Mouse | Or9k2 | 90% | 310 |
| Mouse | Or9k2b | 88% | 313 |
| Rat | Or9k2b | 89% | 313 |
| Rat | Or9k2 | 89% | 311 |
| Cow | OR9K2FP | 83% | 317 |
| Cow | OR9K2G | 84% | 313 |
| Cow | OR9K2DP | 83% | 309 |
| Orang | OR9K1 | 75% | 310 |
| Horse | OR9K2L | 88% | 313 |
| Horse | OR9K2Q | 87% | 313 |
| Horse | OR9K2R | 85% | 311 |
| Chimp | OR9K1P | 74% | 310 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136988 |
| GNF Atlas2 | gnf1h10486_at |
Sequence information
| Nucleotide sequence |
ATGGGTGACAGGGGAACAAGCAATCACTCAGAAATGACTGACTTCATTCTTGCAGGCTTC AGGGTACGCCCAGAGCTCCACATTCTCCTCTTCCTGCTATTTTTGTTTGTTTATGCCATG ATCCTTCTAGGGAATGTTGGGATGATGACCATTATTATGACTGATCCTCGGCTGAACACA CCAATGTATTTTTTCCTAGGCAATCTCTCCTTCATTGATCTTTTCTATTCATCTGTTATT GAACCCAAGGCTATGATCAACTTCTGGTCTGAAAACAAGTCTATCTCCTTTGCAGGCTGT GTGGCCCAGCTCTTTCTCTTTGCCCTCCTCATTGTGACTGAGGGATTTCTCCTGGCGGCC ATGGCTTATGACCGCTTTATTGCCATCTGCAACCCTCTGCTCTACTCTGTTCAAATGTCC ACACGTCTGTGTACTCAGTTGGTGGCTGGTTCCTATTTTTGTGGCTGCATTAGCTCAGTT ATTCAGACTAGCATGACATTTACTTTATCTTTTTGCGCTTCTCGGGCTGTTGACCACTTT TACTGTGATTCTCGCCCACTTCAGAGACTGTCTTGTTCTGATCTCTTTATCCATAGAATG ATATCTTTTTCCTTATCATGTATTATTATCTTGCCTACTATCATAGTCATTATAGTATCT TACATGTATATTGTGTCCACAGTTCTAAAGATACATTCTACTGAGGGACATAAGAAGGCC TTCTCCACCTGCAGCTCTCACCTGGGAGTTGTGAGTGTGCTGTATGGTGCTGTCTTTTTT ATGTATCTCACTCCTGACAGATTTCCTGAGCTGAGTAAAGTGGCATCCTTATGTTACTCC CTAGTCACTCCCATGTTGAATCCTTTGATTTACTCTCTGAGGAACAAAGATGTCCAAGAG GCTCTAAAAAAATTTCTAGAGAAGAAAAATATTATTCTT |
| Conceptual translation |
MGDRGTSNHSEMTDFILAGFRVRPELHILLFLLFLFVYAMILLGNVGMMTIIMTDPRLNT PMYFFLGNLSFIDLFYSSVIEPKAMINFWSENKSISFAGCVAQLFLFALLIVTEGFLLAA MAYDRFIAICNPLLYSVQMSTRLCTQLVAGSYFCGCISSVIQTSMTFTLSFCASRAVDHF YCDSRPLQRLSCSDLFIHRMISFSLSCIIILPTIIVIIVSYMYIVSTVLKIHSTEGHKKA FSTCSSHLGVVSVLYGAVFFMYLTPDRFPELSKVASLCYSLVTPMLNPLIYSLRNKDVQE ALKKFLEKKNIIL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 12 | 100 | -100 | NS | C/T | R/C | 1000GP (YRI, YRI, YRI) |
| 12 | 100 | -100 | SYN | T/C | H/H | 1000GP (YRI) |
| 12 | 55,129,901 | 55,129,901 | NS | C/T | R/C | 1000GP (CEU, CHBJPT) |
| 12 | 55,130,011 | 55,130,011 | SYN | C/T | N/N | 1000GP (CEU) |
| 12 | 55,130,076 | 55,130,076 | NS | A/C | E/A | 1000GP (CEU, CHBJPT) |
| 12 | 55,130,351 | 55,130,351 | NS | G/A | A/T | 1000GP (CHBJPT) |
| 12 | 55,130,388 | 55,130,388 | NS | G/A | R/H | 1000GP (CEU, CHBJPT) |
| 12 | 55,130,530 | 55,130,530 | SYN | T/C | H/H | 1000GP (CEU, CHBJPT) |
| 12 | 55,523,645 | 55,523,645 | SYN | C/T | H/H | rs57538856 (DbSNP) |
| 12 | 55,523,685 | 55,523,685 | NS | C/T | R/C | rs12303066 (DbSNP) |
| 12 | 55,523,860 | 55,523,860 | NS | A/C | E/A | rs7305779 (DbSNP) |
| 12 | 55,524,172 | 55,524,172 | NS | A/G | H/R | rs7306491 (DbSNP) |
| 12 | 55,524,314 | 55,524,314 | SYN | C/T | H/H | rs7137261 (DbSNP) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| R45C | M84T | E103A | R147C | A195T | R207H | G258V | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | R | M | E | R | A | R | G | 69.59 | 1.000 |
| 2 | C | M | A | R | A | H | G | 29.03 | 1.000 |
| 3 | R | M | A | R | A | H | G | 0.31 | 1.000 |
| 4 | C | M | A | R | A | H | V | 0.31 | 1.000 |
| 5 | R | T | E | R | A | R | G | 0.15 | 1.000 |
| 6 | C | M | A | R | T | H | G | 0.15 | 1.000 |
| 7 | R | M | E | C | A | R | G | 0.15 | 1.000 |
| 8 | C | M | A | R | A | R | G | 0.15 | 1.000 |
| 9 | R | M | E | R | T | R | G | 0.08 | 1.000 |
| 10 | C | M | E | R | A | H | G | 0.08 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR9K2.aApr07-unspliced | main_exon | 5UTR | chr12 | 55,129,769 | 55,129,835 | + |
| CDS | chr12 | 55,129,835 | 55,130,773 | + | ||
| 3UTR | chr12 | 55,130,773 | 55,130,776 | + | ||