OR2AJ1 Olfactory Receptor
| Gene Symbol | OR2AJ11 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | AJ |
| Pseudogene | No |
| CORP pseudogene probability score | 0.01 (functional) |
| Aliases | OR1-52 |
| External Ids | HGNC: 15001 GeneBank: AB065626, BK004621, NG_004652 |
| Build #39 labels | OR2AJ1P |
| Chromosomal location | 1:247,933,766-247,934,752 (+) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2L1P | 55.02% | 309 |
| OR2L2 | 54.37% | 309 |
| OR2L8 | 55.81% | 301 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2AJ7 | 80% | 312 |
| Mouse | Or2aj4 | 79% | 314 |
| Rat | Or2aj4-ps | 80% | 316 |
| Cow | OR2AJ10P | 78% | 313 |
| Orang | OR2L3 | 56% | 304 |
| Horse | OR2AJ16P | 80% | 318 |
| Horse | OR2AJ1P | 81% | 306 |
| Chimp | OR2L3C | 56% | 304 |
Sequence information
| Nucleotide sequence |
ATGATGGGCCATCAGAATCACACTTTCAGCAGTGATTTCATACTTTTGGGATTGTTCTCT TCTTCCCCAACAAGTGTGGTCTTCTTCTTAGTTTTATTTGTCATTTTCATTATGAGTGTA ACAGAAAATACGCTCATGATCCTCCTCATTCGCAGTGACTCCCGACTCCACACTCCAATG TATTTTCTGCTCAGCCATCTCTCCTTAATGGATATCTTGCATGTTTCCAACATCGTTCCC AAAATGGTCACTAACTTTCTGTCAGGCAGCAGAACTATTTCATTTGCAGGTTGTGGGTTC CAGGTATTTCTGTCCCTCACCCTCCTGGGTGGTGAGTGCCTTCTCCTGGCTGCAATGTCC TGTGATCGCTATGTGGCTATCTGTCACCCGCTGCGCTATCCGATTCTTATGAAGGAGTAT GCCAGCGCTCTCATGGCTGGAGGCTCCTGGCTCATTGGGGTTTTCAACTCCACAGTCCAC ACAGCTTATGCACTGCAGTTTCCCTTCTGTGGCTCTAGGGCAATTGATCACTTCTTCTGT GAAGTCCCTGCCATGTTGAAGTTGTCCTGTGCAGACACAACACGCTATGAACGAGGGGTT TGTGTAAGTGCTGTGATCTTCCTGCTGATCCCTTTCTCCTTGATCTCTGCTTCTTATGGC CAAATTATTCTTACTGTCCTCCAGATGAAATCATCAGAGGCAAGGAAAAAGTCATTTTCC ACTTGTTCCTTCCACATGATTGTGGTCACGATGTACTATGGGCCATTTATTTTTACATAT ATGAGACCTAAATCATACCACACTCCAGGCCAGGATAAGTTCCTGGCAATATTCTATACG ATCCTCACACCCACACTCAACCCTTTCATCTACAGCTTTAGGAATAAAGATGTTCTGGCG GTGATGAAAAATATGCTCAAAAGTAACTTTCTGCACAAAAAAATGAATAGGAAAATTCCT GAATGTGTGTTCTGTCTATTTCTATGT |
| Conceptual translation |
MMGHQNHTFSSDFILLGLFSSSPTSVVFFLVLFVIFIMSVTENTLMILLIRSDSRLHTPM YFLLSHLSLMDILHVSNIVPKMVTNFLSGSRTISFAGCGFQVFLSLTLLGGECLLLAAMS CDRYVAICHPLRYPILMKEYASALMAGGSWLIGVFNSTVHTAYALQFPFCGSRAIDHFFC EVPAMLKLSCADTTRYERGVCVSAVIFLLIPFSLISASYGQIILTVLQMKSSEARKKSFS TCSFHMIVVTMYYGPFIFTYMRPKSYHTPGQDKFLAIFYTILTPTLNPFIYSFRNKDVLA VMKNMLKSNFLHKKMNRKIPECVFCLFLC Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | C/T | T/M | 1000GP (YRI) |
| 1 | 100 | -100 | SYN | T/C | S/S | 1000GP (YRI, YRI) |
| 1 | 247,933,899 | 247,933,899 | NS | T/C | L/P | 1000GP (CHBJPT) |
| 1 | 247,934,159 | 247,934,159 | NS | C/T | R/C | 1000GP (CEU) |
| 1 | 248,097,461 | 248,097,461 | NS | C/T | R/C | rs61750766 (DbSNP) |
| 1 | 248,097,753 | 248,097,753 | NS | A/T | K/M | rs45624439 (DbSNP) |
| 1 | 248,098,035 | 248,098,035 | NS | G/T | G/V | rs41268443 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 247,074,430 | 248,328,835 | CopyNumber | Variation_6816 (DGV) |
| 1 | 247,714,585 | 248,277,146 | CopyNumber | Variation_3339 (DGV) |
| 1 | 247,753,207 | 248,376,070 | CopyNumber | Variation_8353 (DGV) |
| 1 | 247,753,334 | 248,322,316 | CopyNumber | Variation_2358 (DGV) |
| 1 | 247,849,473 | 248,277,638 | CopyNumber | Variation_48302 (DGV) |
| 1 | 247,849,473 | 248,285,441 | CopyNumber | Variation_48303 (DGV) |
| 1 | 248,060,959 | 249,167,690 | CopyNumber | Variation_8354 (DGV) |
| 1 | 248,096,968 | 248,100,054 | Deletion | #185 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| T43M | L44P | R131C | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | T | L | R | 97.77 | 0.997 |
| 2 | T | L | C | 1.00 | 0.997 |
| 3 | M | L | R | 0.84 | 0.997 |
| 4 | T | P | R | 0.38 | 0.997 |