OR2T10 Olfactory Receptor
| Gene Symbol | OR2T101 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | T |
| Pseudogene | No |
| CORP pseudogene probability score | 0.02 (functional) |
| Aliases | OR1-64, HsOR1.5.46 |
| External Ids | HGNC: 19573 GeneBank: AB065616, BK004478, NM_001004693 |
| Build #39 labels | OR2T10 |
| Chromosomal location | 1:248,592,833-248,593,768 (-) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2T29 | 71.57% | 306 |
| OR2T4 | 72.22% | 306 |
| OR2T5 | 71.24% | 306 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2T4D | 71% | 314 |
| Mouse | Or2t29 | 66% | 310 |
| Rat | Or2t47 | 69% | 298 |
| Cow | OR2T29 | 73% | 305 |
| Orang | OR2T4 | 71% | 305 |
| Horse | OR2T4 | 71% | 309 |
| Chimp | OR2T29 | 73% | 306 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136940 |
| GNF Atlas2 | gnf1h10653_at |
Sequence information
| Nucleotide sequence |
ATGCGGCTGGCCAACCAGACCCTGGGTGGTGACTTTTTCCTGTTGGGAATCTTCAGCCAG ATCTCACACCCTGGCCGCCTCTGCTTGCTTATCTTCAGTATATTTTTGATGGCTGTGTCT TGGAATATTACATTGATACTTCTGATCCACATTGACTCCTCTCTGCATACTCCCATGTAC TTCTTTATAAACCAGCTCTCACTCATAGACTTGACATATATTTCTGTCACTGTCCCCAAA ATGCTGGTGAACCAGCTGGCCAAAGACAAGACCATCTCGGTCCTTGGGTGTGGCACCCAG ATGTACTTCTACCTGCAGTTGGGAGGTGCAGAGTGCTGCCTTCTAGCCGCCATGGCCTAT GACCGCTATGTGGCTATCTGCCATCCTCTCCGTTACTCTGTGCTCATGAGCCATAGGGTA TGTCTCCTCCTGGCATCAGGCTGCTGGTTTGTGGGCTCAGTGGATGGCTTCATGCTCACT CCCATCGCCATGAGCTTCCCCTTCTGCAGATCCCATGAGATTCAGCACTTCTTCTGTGAG GTCCCTGCTGTTTTGAAGCTCTCTTGCTCAGACACCTCACTTTACAAGATTTTCATGTAC TTGTGCTGTGTCATCATGCTCCTGATACCTGTGACGGTCATTTCAGTGTCTTACTACTAT ATCATCCTCACCATCCATAAGATGAACTCAGTTGAGGGTCGGAAAAAGGCCTTCACCACC TGCTCCTCCCACATTACAGTGGTCAGCCTCTTCTATGGAGCTGCTATTTACAACTACATG CTCCCCAGCTCCTACCAAACTCCTGAGAAAGATATGATGTCATCCTTTTTCTACACTATC CTTACACCTGTCTTGAATCCTATCATTTACAGTTTCAGGAATAAGGATGTCACAAGGGCT TTGAAAAAAATGCTGAGCGTGCAGAAACCTCCATAT |
| Conceptual translation |
MRLANQTLGGDFFLLGIFSQISHPGRLCLLIFSIFLMAVSWNITLILLIHIDSSLHTPMY FFINQLSLIDLTYISVTVPKMLVNQLAKDKTISVLGCGTQMYFYLQLGGAECCLLAAMAY DRYVAICHPLRYSVLMSHRVCLLLASGCWFVGSVDGFMLTPIAMSFPFCRSHEIQHFFCE VPAVLKLSCSDTSLYKIFMYLCCVIMLLIPVTVISVSYYYIILTIHKMNSVEGRKKAFTT CSSHITVVSLFYGAAIYNYMLPSSYQTPEKDMMSSFFYTILTPVLNPIIYSFRNKDVTRA LKKMLSVQKPPY Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 248,756,502 | 248,756,502 | NS | A/C | S/A | rs41269353 (DbSNP) |
| 1 | 248,756,994 | 248,756,994 | NS | A/G | C/R | rs28405936 (DbSNP) |
| 1 | 248,756,474 | 248,756,474 | NS | A/G | M/T | rs28664620 (DbSNP) |
| 1 | 248,756,411 | 248,756,411 | NS | A/T | F/Y | rs28733753 (DbSNP) |
| 1 | 248,756,167 | 248,756,167 | NS | C/G | L/F | rs61732484 (DbSNP) |
| 1 | 248,756,835 | 248,756,835 | NS | G/A | P/S | rs61730924 (DbSNP) |
| 1 | 248,756,272 | 248,756,272 | NS | T/G | Q/H | rs61998193 (DbSNP) |
| 1 | 248,756,434 | 248,756,434 | SYN | C/A | T/T | rs61997185 (DbSNP) |
| 1 | 248,756,152 | 248,756,152 | SYN | G/A | S/S | rs61732538 (DbSNP) |
| 1 | 248,756,791 | 248,756,791 | SYN | T/C | S/S | rs61743160 (DbSNP) |
| 1 | 248,593,201 | 248,593,201 | NS | A/C | S/A | 1000GP (CEU) |
| 1 | 100 | -100 | NS | C/G | L/F | 1000GP (YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | C/A | T/T | 1000GP (YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 248,687,510 | 248,865,377 | CopyNumber | Variation_0017 (DGV) |
| 1 | 248,644,944 | 248,790,408 | CopyNumber | Variation_0263 (DGV) |
| 1 | 248,701,948 | 248,877,423 | CopyNumber | Variation_2056 (DGV) |
| 1 | 248,595,681 | 248,817,382 | CopyNumber | Variation_2359 (DGV) |
| 1 | 248,500,109 | 248,865,374 | CopyNumber | Variation_3340 (DGV) |
| 1 | 248,727,928 | 248,796,682 | CopyNumber | Variation_6818 (DGV) |
| 1 | 248,060,959 | 249,167,690 | CopyNumber | Variation_8354 (DGV) |
| 1 | 248,522,680 | 249,158,239 | CopyNumber | Variation_8355 (DGV) |
| 1 | 248,242,528 | 248,817,382 | CopyNumber | Variation_8935 (DGV) |
| 1 | 248,738,074 | 248,795,564 | CopyNumber | Variation_31705 (DGV) |
| 1 | 248,626,918 | 248,830,541 | Inversion | Variation_37092 (DGV) |
| 1 | 248,749,194 | 248,797,213 | CopyNumber | Variation_38068 (DGV) |
| 1 | 248,727,899 | 248,808,428 | CopyNumber | Variation_38963 (DGV) |
| 1 | 248,738,015 | 248,795,518 | CopyNumber | Variation_66540 (DGV) |
| 1 | 248,729,106 | 248,795,518 | CopyNumber | Variation_66541 (DGV) |
| 1 | 248,749,930 | 248,795,305 | CopyNumber | Variation_74998 (DGV) |
| 1 | 248,732,055 | 248,795,305 | CopyNumber | Variation_74999 (DGV) |
| 1 | 248,703,193 | 248,795,305 | CopyNumber | Variation_75000 (DGV) |
| 1 | 248,752,680 | 248,776,055 | CopyNumber | Variation_75001 (DGV) |
| 1 | 248,751,305 | 248,795,305 | CopyNumber | Variation_84995 (DGV) |
| 1 | 248,752,680 | 248,765,055 | CopyNumber | Variation_84996 (DGV) |
| 1 | 248,752,680 | 248,777,430 | CopyNumber | Variation_84997 (DGV) |
| CopyNumber, Deletion | 156 (Hasin) | |||
| 1 | 248,754,134 | 248,757,169 | Deletion, CopyNumber | #23 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| L301F | Y220F | M199T | S190A | A117V | M59V | R26C | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | L | Y | M | S | A | M | R | 91.86 | 0.061 |
| 2 | F | F | T | S | A | M | C | 6.22 | 0.061 |
| 3 | L | Y | M | A | A | M | R | 0.61 | 0.061 |
| 4 | L | Y | T | S | A | M | R | 0.31 | 0.061 |
| 5 | L | Y | M | S | V | M | R | 0.23 | 0.061 |
| 6 | F | Y | T | S | A | M | C | 0.23 | 0.061 |
| 7 | F | F | T | S | A | V | C | 0.23 | 0.352 |
| 8 | L | Y | M | S | A | M | C | 0.15 | 0.061 |
| 9 | F | F | T | S | A | M | R | 0.15 | 0.061 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2T10.aApr07-unspliced | main_exon | 3UTR | chr1 | 248,592,830 | 248,592,833 | - |
| CDS | chr1 | 248,592,833 | 248,593,768 | - | ||