OR2T33 Olfactory Receptor
| Gene Symbol | OR2T331 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | T |
| Pseudogene | No |
| CORP pseudogene probability score | 0.13 (functional) |
| Aliases | OR1-56, HsOR1.5.33 |
| External Ids | HGNC: 31255 GeneBank: AB065961, BK004484, NM_001004695 |
| Build #39 labels | |
| Chromosomal location | 1:248,272,855-248,273,814 (-) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2T12 | 95.31% | 320 |
| OR2T32P | 96.56% | 320 |
| OR2T8 | 93.59% | 312 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2T22 | 78% | 312 |
| Mouse | Or2t44 | 73% | 316 |
| Rat | Or2t44 | 71% | 314 |
| Cow | OR2T13 | 74% | 312 |
| Orang | OR2T32 | 94% | 320 |
| Orang | OR2T32C | 92% | 320 |
| Horse | OR2T69 | 79% | 314 |
| Chimp | OR2T32B | 94% | 320 |
| Chimp | OR2T32 | 94% | 320 |
| Chimp | OR2T8 | 93% | 314 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136995 |
Sequence information
| Nucleotide sequence |
ATGGAGATGAGAAATACTACCCCAGATTTTATTCTCCTAGGACTCTTTAACCACACCAGA GCCCACCAAGTCCTCTTCATGATGGTTCTGAGTATCGTTTTGACCTCCCTGTTTGGCAAT TCCCTCATGATTCTCCTGATTCACTGGGACCACCGGCTCCACACGCCCATGTACTTCCTC CTGAGCCAACTTTCCCTCATGGACATGATGCTGGTTTCCACCACTGTGCCCAAAATGGCG GCTGACTACTTGACCGGAAGTAAGGCCATCTCCCGCGCTGGCTGTGGTGTGCAGATCTTC TTCCTCCCCACACTGGGTGGTGGAGAGTGCTTCCTCTTAGCAGCCATGGCCTATGACCGC TATGCGGCTGTCTGCCACCCACTCCGATATCCCACTCTCATGAGCTGGCAGCTGTGCCTG AGGATGACCATGTCGTGTTGGCTCCTGGGTGCAGCTGACGGGCTCCTGCAGGCTGTTGTT ACCCTGAGCTTCCCATATTGTGGTGCACACGAGATCGATCACTTCTTCTGCGAGACCCCC GTGCTGGTGCGTTTGGCTTGTGCTGACACTTCAGTCTTCGAAAACGCCATGTACATCTGC TGTGTGTTAATGCTCCTGGTCCCCTTTTCCCTCATCCTGTCCTCCTATGGTCTCATCCTC GCTGCTGTTCTGCACATGCGCTCTACAGAAGCCCGCAAGAAGGCCTTTGCCACCTGCTCT TCACATGTGGCTGTGGTGGGACTCTTTTATGGAGCTGCCATTTTTACCTATATGAGACCC AAATCCCATAGGTCCACTAACCATGACAAGGTTGTGTCAGCCTTCTATACTATGTTCACC CCTTTACTAAACCCCCTCATCTACAGTGTGAAGAACAGTGAGGTGAAGGGAGCCCTGAAA CGGTGGCTGGGGACGTGTGTAAACATAAAACACCAGCAAAATGAGGCCCACAGGTCAAGA |
| Conceptual translation |
MEMRNTTPDFILLGLFNHTRAHQVLFMMVLSIVLTSLFGNSLMILLIHWDHRLHTPMYFL LSQLSLMDMMLVSTTVPKMAADYLTGSKAISRAGCGVQIFFLPTLGGGECFLLAAMAYDR YAAVCHPLRYPTLMSWQLCLRMTMSCWLLGAADGLLQAVVTLSFPYCGAHEIDHFFCETP VLVRLACADTSVFENAMYICCVLMLLVPFSLILSSYGLILAAVLHMRSTEARKKAFATCS SHVAVVGLFYGAAIFTYMRPKSHRSTNHDKVVSAFYTMFTPLLNPLIYSVKNSEVKGALK RWLGTCVNIKHQQNEAHRSR Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | NS | C/G | G/A | 1000GP (YRI) |
| 1 | 248,273,336 | 248,273,336 | NS | A/G | V/A | 1000GP (CEU) |
| 1 | 248,436,312 | 248,436,312 | NS | T/C | N/D | rs72475088 (DbSNP) |
| 1 | 248,436,506 | 248,436,506 | NS | A/G | M/T | rs56404069 (DbSNP) |
| 1 | 248,436,611 | 248,436,611 | NS | A/G | V/A | rs10888338 (DbSNP) |
| 1 | 248,436,616 | 248,436,616 | SYN | A/G | C/C | rs71538179 (DbSNP) |
| 1 | 248,436,695 | 248,436,695 | NS | C/T | R/K | rs71642437 (DbSNP) |
| 1 | 248,436,805 | 248,436,805 | SYN | G/T | T/T | rs28399248 (DbSNP) |
| 1 | 248,436,809 | 248,436,809 | NS | A/G | L/P | rs61832700 (DbSNP) |
| 1 | 248,436,811 | 248,436,811 | SYN | C/G | L/L | rs61832701 (DbSNP) |
| 1 | 248,437,028 | 248,437,028 | NS | A/G | L/P | rs74155265 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 248,060,959 | 249,167,690 | CopyNumber | Variation_8354 (DGV) |
| 1 | 248,242,528 | 248,817,382 | CopyNumber | Variation_8935 (DGV) |
| 1 | 248,319,780 | 248,490,372 | CopyNumber | Variation_31702 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| I309L | G297A | A169V | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | I | G | V | 66.05 | 0.285 |
| 2 | I | G | A | 32.41 | 0.285 |
| 3 | L | G | V | 0.77 | 0.285 |
| 4 | L | G | A | 0.46 | 0.285 |
| 5 | I | A | V | 0.23 | 0.285 |
| 6 | I | A | A | 0.08 | 0.285 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2T33.aApr07-unspliced | main_exon | 3UTR | chr1 | 248,272,852 | 248,272,855 | - |
| CDS | chr1 | 248,272,855 | 248,273,814 | - | ||