OR4A15 Olfactory Receptor
| Gene Symbol | OR4A151 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 1 (pseudogene) |
| Aliases | OR11-118, HsOR11.11.4, ORL3411 |
| External Ids | HGNC: 15152 GeneBank: AB065776, AF399578, BK004248, NM_001005275 ORDB: ORL3411 |
| Build #39 labels | OR4A15 |
| Chromosomal location | 11:55,367,974-55,368,915 (+) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4A21P | 90.58% | 308 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4A2 | 69% | 303 |
| Mouse | Or4a15 | 83% | 314 |
| Rat | Or4a15 | 85% | 301 |
| Rat | Or4a15b | 82% | 307 |
| Cow | OR4A15P | 81% | 309 |
| Orang | OR4A47P | 63% | 304 |
| Horse | OR4A148P | 67% | 313 |
| Chimp | OR4A21P | 90% | 309 |
Sequence information
| Nucleotide sequence |
ATGAAAAATAAGAACAATGTGACTGAATTTATCCTCTTAGGGCTCACACAGAACCCTGAG GGGCAAAAGGTTTTATTTGTCACATTCTTACTAATCTACATGGTGACGATAATGGGCAAC CTGCTTATCATAGTGACCATCATGGCCAGCCAGTCCCTGGGTTCCCCCATGTACTTTTTT CTGGCTTCTTTATCATTCATAGATACCGTCTATTCTACTGCATTTGCTCCCAAAATGATT GTTGACTTGCTCTCTGAGAAAAAGACCATTTCCTTTCAGGGTTGTATGGCTCAACTTTTT ATGGATCATTTATTTGCTGGTGCTGAAGTCATTCTTCTGGTGGTAATGGCCTATGATCGA TACATGGCCATCTGTAAGCCTCTTCATGAATTGATCACCATGAATCGTCGAGTCTGTGTT CTTATGCTGTTGGCGGCCTGGATTGGAGGCTTTCTTCACTCATTGGTTCAATTTCTCTTT ATTTATCAGCTCCCTTTCTGTGGACCCAATGTCATTGACAACTTCCTGTGTGATTTGTAT CCCTTATTGAAACTTGCTTGCACCAATACCTATGTCACTGGGCTTTCTATGATAGCTAAT GGAGGAGCGATTTGTGCTGTCACCTTCTTCACTATCCTGCTTTCCTATGGGGTCATATTA CACTCTCTTAAGACTCAGAGTTTGGAAGGGAAACGAAAAGCTTTCTACACCTGTGCATCC CACGTCACTGTGGTCATTTTATTCTTTGTCCCCTGTATCTTCTTGTATGCAAGGCCCAAT TCTACTTTTCCCATTGATAAATCCATGACTGTAGTTCTAACTTTTATAACTCCCATGCTG AACCCACTAATCTATACCCTGAAGAATGCAGAAATGAAAAGTGCCATGAGGAAACTTTGG AGTAAAAAAGTAAGCTTAGCTGGGAAATGGCTGTATCACTCA |
| Conceptual translation |
MKNKNNVTEFILLGLTQNPEGQKVLFVTFLLIYMVTIMGNLLIIVTIMASQSLGSPMYFF LASLSFIDTVYSTAFAPKMIVDLLSEKKTISFQGCMAQLFMDHLFAGAEVILLVVMAYDR YMAICKPLHELITMNRRVCVLMLLAAWIGGFLHSLVQFLFIYQLPFCGPNVIDNFLCDLY PLLKLACTNTYVTGLSMIANGGAICAVTFFTILLSYGVILHSLKTQSLEGKRKAFYTCAS HVTVVILFFVPCIFLYARPNSTFPIDKSMTVVLTFITPMLNPLIYTLKNAEMKSAMRKLW SKKVSLAGKWLYHS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 55,136,345 | 55,136,345 | NS | A/T | H/L | rs61753616 (DbSNP) |
| 11 | 55,136,279 | 55,136,279 | NS | C/T | T/I | rs61753622 (DbSNP) |
| 11 | 55,136,219 | 55,136,219 | NS | C/T | A/V | rs7927370 (DbSNP) |
| 11 | 55,135,689 | 55,135,689 | SYN | A/T | I/I | rs61916184 (DbSNP) |
| 11 | 55,136,019 | 55,136,019 | SYN | C/G | T/T | rs61748701 (DbSNP) |
| 11 | 55,368,213 | 55,368,213 | SYN | T/A | I/I | 1000GP (CEU) |
| 11 | 55,368,400 | 55,368,400 | SYN | C/T | L/L | 1000GP (CEU) |
| 11 | 55,368,743 | 55,368,743 | NS | C/T | A/V | 1000GP (CEU) |
| 11 | 55,368,649 | 55,368,649 | nonsense SNP | C/T | Q/* | 1000GP (CHBJPT) |
| 11 | 100 | -100 | NS | C/G | T/S | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 54,835,623 | 55,879,426 | CopyNumber | Variation_8690 (DGV) |
| 11 | 55,121,706 | 55,340,753 | CopyNumber | Variation_9185 (DGV) |
| 11 | 55,083,434 | 55,156,434 | CopyNumber | Variation_48825 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| Q256* | V272I | A287V | T304S | T307I | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | Q | V | A | T | T | 93.39 | 1.000 |
| 2 | Q | V | V | T | T | 2.76 | 1.000 |
| 3 | Q | V | A | S | T | 2.23 | 1.000 |
| 4 | * | V | A | T | T | 1.31 | 1.200 |
| 5 | Q | V | A | T | I | 0.15 | 1.000 |
| 6 | Q | I | A | T | T | 0.15 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR4A15.aApr07-unspliced | main_exon | 5UTR | chr11 | 55,367,884 | 55,367,974 | + |
| CDS | chr11 | 55,367,974 | 55,368,915 | + | ||
| 3UTR | chr11 | 55,368,915 | 55,368,918 | + | ||