OR4C15 Olfactory Receptor
| Gene Symbol | OR4C151 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | C |
| Pseudogene | No |
| CORP pseudogene probability score | 0.01 (functional) |
| Aliases | OR11-134, OR11-127, HsOR11.11.15, ORL3313 |
| External Ids | HGNC: 15171 GeneBank: AB065771, BK004319, BK004320, NM_001001920 ORDB: ORL3313 |
| Build #39 labels | OR4C15 |
| Chromosomal location | 11:55,554,469-55,555,416 (+) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4C10P | 67.66% | 303 |
| OR4C46 | 63.87% | 310 |
| OR4C9P | 65.02% | 303 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4C10 | 66% | 310 |
| Mouse | Or4c15 | 83% | 311 |
| Mouse | Or4c15b | 80% | 311 |
| Rat | Or4c15 | 82% | 311 |
| Cow | OR4C15P | 80% | 311 |
| Orang | OR4C9P | 61% | 311 |
| Horse | OR4C15P | 82% | 311 |
| Horse | OR4C15D | 81% | 311 |
| Chimp | OR4C10P | 68% | 303 |
Sequence information
| Nucleotide sequence |
ATGCAAAACCAAAGCTTTGTAACTGAGTTTGTCCTCCTGGGACTTTCACAGAATCCAAAT GTTCAGGAAATAGTATTTGTTGTATTTTTGTTTGTCTACATTGCAACTGTTGGGGGCAAC ATGCTAATTGTAGTAACCATTCTCAGCAGCCCTGCTCTTCTGGTGTCTCCTATGTACTTC TTCTTGGGCTTCCTGTCCTTCCTGGATGCGTGCTTCTCATCTGTCATCACCCCAAAGATG ATTGTAGACTCCCTCTATGTGACAAAAACCATCTCTTTTGAAGGCTGCATGATGCAGCTC TTTGCTGAACACTTCTTTGCTGGGGTGGAGGTGATTGTCCTCACAGCCATGGCCTATGAT CGTTATGTGGCCATTTGCAAGCCCTTGCATTACTCTTCTATCATGAACAGGAGGCTCTGT GGCATTCTGATGGGGGTAGCCTGGACAGGGGGCCTCTTGCATTCCATGATACAAATTCTT TTTACTTTCCAGCTTCCCTTTTGTGGCCCCAATGTCATCAATCACTTTATGTGTGACTTG TACCCGTTACTGGAGCTTGCCTGCACTGATACTCACATCTTTGGCCTCATGGTGGTCATC AACAGTGGGTTTATCTGCATCATAAACTTCTCCTTGTTGCTTGTCTCCTATGCTGTCATC TTGCTCTCTCTGAGAACACACAGTTCTGAAGGGCGCTGGAAAGCTCTCTCCACCTGTGGA TCTCACATTGCTGTTGTGATTTTGTTCTTTGTCCCATGCATATTTGTATATACACGACCT CCATCTGCTTTTTCCCTTGACAAAATGGCGGCAATATTTTATATCATCTTAAATCCCTTG CTCAATCCTTTGATTTACACTTTCAGGAATAAGGAAGTAAAACAGGCCATGAGGAGAATA TGGAACAGACTGATGGTGGTTTCTGATGAGAAAGAAAATATTAAACTT |
| Conceptual translation |
MQNQSFVTEFVLLGLSQNPNVQEIVFVVFLFVYIATVGGNMLIVVTILSSPALLVSPMYF FLGFLSFLDACFSSVITPKMIVDSLYVTKTISFEGCMMQLFAEHFFAGVEVIVLTAMAYD RYVAICKPLHYSSIMNRRLCGILMGVAWTGGLLHSMIQILFTFQLPFCGPNVINHFMCDL YPLLELACTDTHIFGLMVVINSGFICIINFSLLLVSYAVILLSLRTHSSEGRWKALSTCG SHIAVVILFFVPCIFVYTRPPSAFSLDKMAAIFYIILNPLLNPLIYTFRNKEVKQAMRRI WNRLMVVSDEKENIKL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 55,322,611 | 55,322,635 | Del(25) | -/TCTCTGAGAACACACAGTTCTGAAG | rs72140406 (DbSNP) | |
| 11 | 55,322,818 | 55,322,818 | nonsense SNP | G/T | E/* | rs72908448 (DbSNP) |
| 11 | 55,322,464 | 55,322,464 | NS | A/C | N/H | rs61919569 (DbSNP) |
| 11 | 55,322,099 | 55,322,099 | NS | A/C | D/A | rs17496724 (DbSNP) |
| 11 | 55,322,539 | 55,322,539 | NS | A/G | I/V | rs12790125 (DbSNP) |
| 11 | 55,322,638 | 55,322,638 | NS | C/T | R/C | rs12225462 (DbSNP) |
| 11 | 55,322,606 | 55,322,606 | NS | C/T | S/L | rs17581700 (DbSNP) |
| 11 | 55,322,020 | 55,322,020 | NS | C/T | L/F | rs11828099 (DbSNP) |
| 11 | 55,322,490 | 55,322,490 | SYN | A/G | P/P | rs61919570 (DbSNP) |
| 11 | 55,322,211 | 55,322,211 | SYN | A/G | K/K | rs9804659 (DbSNP) |
| 11 | 55,322,298 | 55,322,298 | SYN | C/T | A/A | rs8181485 (DbSNP) |
| 11 | 55,554,822 | 55,554,822 | SYN | C/T | A/A | 1000GP (CEU, CHBJPT) |
| 11 | 55,555,162 | 55,555,162 | NS | C/T | R/C | 1000GP (CEU, CHBJPT) |
| 11 | 55,554,623 | 55,554,623 | NS | C/A | A/D | 1000GP (CEU) |
| 11 | 55,554,988 | 55,554,988 | NS | A/C | N/H | 1000GP (CEU) |
| 11 | 55,554,946 | 55,554,946 | NS | C/A | L/I | 1000GP (CEU) |
| 11 | 55,555,063 | 55,555,063 | NS | G/A | V/I | 1000GP (CEU, CHBJPT) |
| 11 | 55,554,735 | 55,554,735 | SYN | A/G | K/K | 1000GP (CEU, CHBJPT) |
| 11 | 55,555,014 | 55,555,014 | SYN | G/A | P/P | 1000GP (CEU) |
| 11 | 55,555,130 | 55,555,130 | NS | T/C | L/S | 1000GP (CEU) |
| 11 | 100 | -100 | SYN | A/G | K/K | 1000GP (YRI, YRI, YRI) |
| 11 | 100 | -100 | NS | G/A | V/I | 1000GP (YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 55,153,930 | 55,816,828 | CopyNumber | Variation_0308 (DGV) |
| 11 | 55,222,420 | 55,621,884 | CopyNumber | Variation_3852 (DGV) |
| 11 | 54,835,623 | 55,879,426 | CopyNumber | Variation_8690 (DGV) |
| 11 | 55,121,706 | 55,340,753 | CopyNumber | Variation_9185 (DGV) |
| 11 | 55,276,602 | 55,355,722 | CopyNumber | Variation_9186 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| F80L | A106D | M151L | G204E | L214I | N228H | V253I | N263D | L275S | R286C | R286H | E346* | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | F | A | M | G | L | N | V | N | L | R | R | E | 64.13 | 0.036 |
| 2 | F | A | M | G | L | N | I | N | L | R | R | E | 17.67 | 0.036 |
| 3 | F | A | M | G | L | N | V | N | L | C | R | E | 13.21 | 0.036 |
| 4 | F | D | M | G | I | H | V | N | S | R | R | E | 2.53 | 0.036 |
| 5 | L | A | M | E | L | N | V | N | L | R | R | E | 0.84 | 0.036 |
| 6 | F | A | M | G | L | N | V | N | L | R | H | E | 0.46 | 0.036 |
| 7 | L | A | L | E | L | N | V | N | L | R | R | E | 0.46 | 0.036 |
| 8 | F | D | M | G | I | H | V | N | L | R | R | E | 0.23 | 0.036 |
| 9 | F | D | M | G | L | H | V | N | S | R | R | E | 0.15 | 0.036 |
| 10 | F | A | M | G | L | N | V | N | L | R | R | * | 0.15 | 1.200 |
| 11 | F | A | M | G | L | N | V | D | L | R | R | E | 0.08 | 0.036 |
| 12 | F | A | M | G | I | N | V | N | L | R | R | E | 0.08 | 0.036 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR4C15.aApr07-unspliced | main_exon | 5UTR | chr11 | 55,554,307 | 55,554,469 | + |
| CDS | chr11 | 55,554,469 | 55,555,416 | + | ||
| 3UTR | chr11 | 55,555,416 | 55,555,419 | + | ||