OR4D5 Olfactory Receptor
| Gene Symbol | OR4D51 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | D |
| Pseudogene | No |
| CORP pseudogene probability score | 0.16 (functional) |
| Aliases | OR11-276, HsOR11.18.6, ORL3292 |
| External Ids | HGNC: 14852 GeneBank: AB065760, BK004316, NM_001001965 ORDB: ORL3292 |
| Build #39 labels | OR4D5 |
| Chromosomal location | 11:123,939,617-123,940,570 (+) |
| Cluster | 11@124 |
| Synteny | CLIC#29 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4D1 | 61.79% | 301 |
| OR4D6 | 59.68% | 315 |
| OR4D9 | 62.5% | 304 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4D9D | 61% | 311 |
| Mouse | Or4d5 | 90% | 314 |
| Rat | Or4d5 | 90% | 314 |
| Cow | OR4D9D | 61% | 315 |
| Orang | OR4D5P | 97% | 309 |
| Horse | OR4D5B | 80% | 318 |
| Chimp | OR4D9 | 63% | 304 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136945 |
| GNF Atlas2 | gnf1h05563_s_at |
Sequence information
| Nucleotide sequence |
ATGAATCCAGCAAATCATTCCCAGGTGGCAGGATTTGTTCTACTGGGGCTCTCTCAGGTT TGGGAGCTTCGGTTTGTTTTCTTCACTGTTTTCTCTGCTGTGTATTTTATGACTGTAGTG GGAAACCTTCTTATTGTGGTCATAGTGACCTCCGACCCACACCTGCACACAACCATGTAT TTTCTCTTGGGCAATCTTTCTTTCCTGGACTTTTGCTACTCTTCCATCACAGCACCTAGG ATGCTGGTTGACTTGCTCTCAGGCAACCCTACCATTTCCTTTGGTGGATGCCTGACTCAA CTCTTCTTCTTCCACTTCATTGGAGGCATCAAGATCTTCCTGCTGACTGTCATGGCGTAT GACCGCTACATTGCCATTTCCCAGCCCCTGCACTACACGCTCATTATGAATCAGACTGTC TGTGCACTCCTTATGGCAGCCTCCTGGGTGGGGGGCTTCATCCACTCCATAGTACAGATT GCATTGACTATCCAGCTGCCATTCTGTGGGCCTGACAAGCTGGACAACTTTTATTGTGAT GTGCCTCAGCTGATCAAATTGGCCTGCACAGATACCTTTGTCTTAGAGCTTTTAATGGTG TCTAACAATGGCCTGGTGACCCTGATGTGTTTTCTGGTGCTTCTGGGATCGTACACAGCA CTGCTAGTCATGCTCCGAAGCCACTCACGGGAGGGCCGCAGCAAGGCCCTGTCTACCTGT GCCTCTCACATTGCTGTGGTGACCTTAATCTTTGTGCCTTGCATCTACGTCTATACAAGG CCTTTTCGGACATTCCCCATGGACAAGGCCGTCTCTGTGCTATACACAATTGTCACCCCC ATGCTGAATCCTGCCATCTATACCCTGAGAAACAAGGAAGTGATCATGGCCATGAAGAAG CTGTGGAGGAGGAAAAAGGACCCTATTGGTCCCCTGGAGCACAGACCCTTACAT |
| Conceptual translation |
MNPANHSQVAGFVLLGLSQVWELRFVFFTVFSAVYFMTVVGNLLIVVIVTSDPHLHTTMY FLLGNLSFLDFCYSSITAPRMLVDLLSGNPTISFGGCLTQLFFFHFIGGIKIFLLTVMAY DRYIAISQPLHYTLIMNQTVCALLMAASWVGGFIHSIVQIALTIQLPFCGPDKLDNFYCD VPQLIKLACTDTFVLELLMVSNNGLVTLMCFLVLLGSYTALLVMLRSHSREGRSKALSTC ASHIAVVTLIFVPCIYVYTRPFRTFPMDKAVSVLYTIVTPMLNPAIYTLRNKEVIMAMKK LWRRKKDPIGPLEHRPLH Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 123,811,013 | 123,811,013 | SYN | A/G | R/R | rs17127996 (DbSNP) |
| 11 | 123,939,785 | 123,939,785 | NS | A/C | T/P | 1000GP (CEU) |
| 11 | 123,940,306 | 123,940,306 | SYN | G/A | R/R | 1000GP (CHBJPT) |
| 11 | 100 | -100 | NS | G/T | C/F | 1000GP (YRI, YRI) |
| 11 | 100 | -100 | SYN | G/T | L/L | 1000GP (YRI, YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| T57P | C141F | D175V | R233C | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | T | C | D | R | 96.54 | 0.323 |
| 2 | T | C | D | C | 1.46 | 0.282 |
| 3 | P | C | D | R | 0.84 | 0.323 |
| 4 | T | C | V | R | 0.69 | 0.323 |
| 5 | T | F | D | R | 0.46 | 0.323 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR4D5.aApr07-unspliced | main_exon | CDS | chr11 | 123,939,617 | 123,940,570 | + |
| 3UTR | chr11 | 123,940,570 | 123,940,573 | + | ||