OR4E1P Olfactory Receptor
| Gene Symbol | OR4E1P1 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | E |
| Pseudogene | Yes |
| CORP pseudogene probability score | |
| Aliases | OR14-43, AE000658, HsOR14.2.6P, ORL3717 |
| External Ids | HGNC: 8296 GeneBank: AB065562, AF399450, BK004671, NG_004135 ORDB: ORL3717 |
| Build #39 labels | OR4E1P |
| Chromosomal location | 14:21,669,991-21,670,935 (-) |
| Cluster | 14@22b |
| Synteny | CLIC#35 |
| Remarks | Segregating Pseudo Gene, a polymorphism of 2 bp insertion (AC) at positions 584-585 |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4E2 | 63.16% | 304 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4E1 | 85% | 316 |
| Mouse | Or4e1 | 86% | 312 |
| Rat | Or4e1 | 87% | 312 |
| Cow | OR4E1 | 88% | 316 |
| Orang | OR4E1 | 96% | 316 |
| Horse | OR4E1 | 89% | 316 |
| Chimp | OR4E1 | 97% | 316 |
Sequence information
| Nucleotide sequence |
ATGGAAGAGGCCATCCTACTCAATCAAACTTCTTTAGTGACATATTTTCGGCTTAGAGGT TTATCTGTAAATCATAAGGCACGGATAGCTATGTTTTCCATGTTCCTCATTTTTTATGTC CTGACACTGATTGGGAATGTTCTCATTGTCATAACTATTATCTATGACCACCGGCTCCAT ACTCCCATGTATTTCTTCCTCAGCAACCTGTCCTTTATTGATGTCTGCCACTCCACTGTC ACTGTCCCCAAGATGCTGAGAGACGTGTGGTCAGAGGAAAAGCTCATCTCTTTTGATGCC TGTGTGACCCAGATGTTCTTCCTGCACCTCTTTGCCTGCACAGAGATCTTCCTCCTCACC GTCATGGCCTATGATCGGTATGTGGCCATCTGTAAACCCCTGCAGTACATGATAGTGATG AACTGGAAGGTATGTGTGCTGCTGGCTGTGGCCCTCTGGACAGGAGGGACCATCCACTCC ATAGCCCTCACCTCCCTTACCATCAAGCTGCCCTACTGTGGTCCTGATGAGATTGACAAC TTCTTCTGTGATGTACCTCAGGTGATCAAGCTGGCCTGCATTGACACACCCACGTCCTTG AGATCCTCATTGTCTCCAACAGTGGATTGATCTCCGTGGTCTGTTTTGTGGTCCTGGTGG TGTCCTACGCAGTCATCCTGGTGAGTCTGAGGCAGCAGATCTCCAAGGGCAAGTGGAAGG CCCTGTCCACCTGTGCAGCCCATCTCACTGTAGTTACACTGTTCCTGGGACACTGCATCT TCATCTATTCCCGCCCATCCACCAGCCTCCCAGAGGACAAGGCAGTATCTGTGTTTTTCA CTGCAGTCACCCCCCTGCTGAACCCCATTATCTATACCCTTAGGAATGAAGAAATGAAGA GTGCCTTAAACAAGTTAGTGGGGAGAAAAGAGAGAAAAGAAGAAAAA |
| Conceptual translation |
MEEAILLNQTSLVTYFRLRGLSVNHKARIAMFSMFLIFYVLTLIGNVLIVITIIYDHRLH TPMYFFLSNLSFIDVCHSTVTVPKMLRDVWSEEKLISFDACVTQMFFLHLFACTEIFLLT VMAYDRYVAICKPLQYMIVMNWKVCVLLAVALWTGGTIHSIALTSLTIKLPYCGPDEIDN FFCDVPQVIKLACIDTP/VLEILIVSNSGLISVVCFVVLVVSYAVILVSLRQQISKGKW KALSTCAAHLTVVTLFLGHCIFIYSRPSTSLPEDKAVSVFFTAVTPLLNPIIYTLRNEEM KSALNKLVGRKERKEEK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 14 | 100 | -100 | SNP | C/T | 1000GP (YRI, YRI, YRI, YRI, YRI) | |
| 14 | 21,670,115 | 21,670,115 | SNP | G/A | 1000GP (CEU, CHBJPT) | |
| 14 | 21,670,224 | 21,670,224 | SNP | A/G | 1000GP (CEU, CHBJPT) | |
| 14 | 21,670,234 | 21,670,334 | SNP | A/C | 1000GP (YRI) | |
| 14 | 21,670,262 | 21,670,262 | SNP | A/T | 1000GP (YRI) | |
| 14 | 21,670,334 | 21,670,334 | SNP | A/C | 1000GP (CEU) | |
| 14 | 21,670,341 | 21,670,341 | SNP | G/T | 1000GP (CEU, CHBJPT, YRI) | |
| 14 | 21,670,852 | 21,670,852 | SNP | C/G | 1000GP (CHBJPT) | |
| 14 | 21,670,854 | 21,670,854 | SNP | G/A | 1000GP (CEU, CHBJPT) | |
| 14 | 22,138,228 | 22,138,228 | SNP | C/T | rs73588741 (DbSNP) | |
| 14 | 22,138,269 | 22,138,269 | SNP | G/T | rs17109034 (DbSNP) | |
| 14 | 22,138,328 | 22,138,328 | SNP | A/G | rs7144135 (DbSNP) | |
| 14 | 22,138,352 | 22,138,352 | SNP | G/T | rs61974769 (DbSNP) | |
| 14 | 22,138,437 | 22,138,437 | SNP | A/G | rs970025 (DbSNP) | |
| 14 | 22,138,475 | 22,138,475 | SNP | A/T | rs17109038 (DbSNP) | |
| 14 | 22,138,547 | 22,138,547 | SNP | A/C | rs12883831 (DbSNP) | |
| 14 | 22,138,554 | 22,138,554 | SNP | G/T | rs10143044 (DbSNP) | |
| 14 | 22,138,562 | 22,138,563 | Del(2) | -/GT | rs5807088 (DbSNP) | |
| 14 | 22,138,565 | 22,138,566 | Del(2) | -/TG | rs3035516 (DbSNP) | |
| 14 | 22,138,566 | 22,138,567 | Del(2) | -/GT | rs34586214 (DbSNP) | |
| 14 | 22,138,886 | 22,138,886 | SNP | C/T | rs60080686 (DbSNP) | |
| 14 | 22,139,067 | 22,139,067 | SNP | C/G | rs72686097 (DbSNP) | |
| 14 | 22,139,069 | 22,139,069 | SNP | A/G | rs72686098 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 14 | 21,931,624 | 22,169,502 | CopyNumber | Variation_5318 (DGV) |
| 14 | 22,136,204 | 22,139,250 | CopyNumber | #149 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.