OR4K17 Olfactory Receptor
| Gene Symbol | OR4K171 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | K |
| Pseudogene | No |
| CORP pseudogene probability score | 0.19 (functional) |
| Aliases | OR14-29, HsOR14.1.22, ORL3691 |
| External Ids | HGNC: 15355 GeneBank: AB065891, BK004450, NM_001004715 ORDB: ORL3691 |
| Build #39 labels | OR4K17 |
| Chromosomal location | 14:20,117,500-20,118,435 (+) |
| Cluster | 14@20b |
| Synteny | CLIC#32 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4K15 | 63.79% | 301 |
| OR4K3P | 61.44% | 306 |
| OR4K5 | 60.33% | 305 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4K14 | 62% | 310 |
| Mouse | Or4k15 | 64% | 301 |
| Rat | Or4k15 | 63% | 307 |
| Cow | OR4K14 | 64% | 302 |
| Orang | OR4K15 | 63% | 310 |
| Horse | OR4K17C | 87% | 312 |
| Horse | OR4K17B | 84% | 312 |
| Chimp | OR4K15 | 62% | 310 |
Expression evidences
| Source | Accession |
|---|---|
| GNF Atlas2 | gnf1h02179_at |
| GNF Atlas2 | gnf1h11365_s_at |
Sequence information
| Nucleotide sequence |
ATGAAACTATTAAATCAATCTCAAGTGTCAGAATTCATTTTGCTGGGACTGACCAGCTCC CAGGATGTAGAGTTTCTTCTCTTTGCCCTCTTCTCGGTTATCTATGTGGTCACAGTTTTG GGTAACCTTCTTATTATAGTCACAGTGTTTAACACCCCTAACCTGAATACTCCCATGTAT TTTCTCCTTGGTAATCTCTCTTTTGTAGATATGACCCTTGCTTCTTTTGCCACCCCTAAG GTGATTCTGAACTTGTTAAAAAAGCAGAAGGTAATTTCTTTTGCTGGGTGCTTCACTCAG ATATTTCTCCTTCACTTACTGGGTGGGGTTGAAATGGTACTGTTGGTCTCCATGGCTTTT GACAGATATGTGGCCATTTGTAAGCCCCTACACTACATGACCATCATGAACAAGAAGGTA TGTGTTTTGCTTGTAGTGACCTCATGGCTCTTGGGTCTCCTTCACTCAGGGTTTCAGATA CCATTTGCTGTGAACTTGCCCTTTTGTGGTCCCAATGTGGTAGACAGCATTTTTTGTGAC CTCCCTTTGGTTACTAAGCTTGCCTGTATAGACATATATTTTGTACAGGTAGTCATTGTT GCCAACAGTGGCATAATCTCCCTGAGCTGTTTCATTATTTTGCTTATCTCCTACAGTCTG ATCCTCATAACCATTAAGAACCACTCTCCTACTGGGCAATCTAAAGCCCGTTCCACTTTG ACTGCTCACATCACAGTGGTGATTCTCTTCTTTGGCCCATGCATCTTTATCTACATTTGG CCCTTCGGCAACCACTCTGTAGATAAGTTCCTTGCTGTGTTTTATACCATCATCACTCCT ATCTTGAATCCAATTATCTATACTCTGAGAAACAAAGAAATGAAGATATCCATGAAAAAA CTCTGGAGAGCTTTTGTGAATTCTAGAGAAGATACT |
| Conceptual translation |
MKLLNQSQVSEFILLGLTSSQDVEFLLFALFSVIYVVTVLGNLLIIVTVFNTPNLNTPMY FLLGNLSFVDMTLASFATPKVILNLLKKQKVISFAGCFTQIFLLHLLGGVEMVLLVSMAF DRYVAICKPLHYMTIMNKKVCVLLVVTSWLLGLLHSGFQIPFAVNLPFCGPNVVDSIFCD LPLVTKLACIDIYFVQVVIVANSGIISLSCFIILLISYSLILITIKNHSPTGQSKARSTL TAHITVVILFFGPCIFIYIWPFGNHSVDKFLAVFYTIITPILNPIIYTLRNKEMKISMKK LWRAFVNSREDT Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 14 | 20,586,532 | 20,586,532 | NS | A/C | K/Q | rs61751876 (DbSNP) |
| 14 | 20,585,924 | 20,585,924 | NS | A/G | Q/R | rs61733476 (DbSNP) |
| 14 | 20,586,042 | 20,586,042 | NS | C/G | N/K | rs8005245 (DbSNP) |
| 14 | 20,586,432 | 20,586,432 | SYN | C/T | Y/Y | rs9323534 (DbSNP) |
| 14 | 20,586,519 | 20,586,519 | SYN | C/T | Y/Y | rs12101112 (DbSNP) |
| 14 | 20,117,883 | 20,117,883 | NS | G/C | K/N | 1000GP (CEU, CHBJPT) |
| 14 | 20,117,765 | 20,117,765 | NS | A/G | Q/R | 1000GP (CEU) |
| 14 | 20,118,273 | 20,118,273 | SYN | C/T | Y/Y | 1000GP (CEU, CHBJPT) |
| 14 | 100 | -100 | NS | G/C | K/N | 1000GP (YRI) |
| 14 | 100 | -100 | SYN | C/T | Y/Y | 1000GP (YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 14 | 20,203,125 | 20,626,160 | CopyNumber | Variation_8763 (DGV) |
| 14 | 20,203,125 | 20,716,841 | CopyNumber | Variation_8765 (DGV) |
| 14 | 20,203,125 | 20,655,466 | CopyNumber | Variation_34656 (DGV) |
| 14 | 20,540,298 | 20,587,047 | CopyNumber | Variation_35235 (DGV) |
| 14 | 20,585,559 | 20,588,594 | Deletion | #279 (Waszak) |
| 14 | 20,585,466 | 20,585,692 | Del(-15) | #22(modil) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| Q120R | K159N | R268H | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | Q | K | R | 56.84 | 0.434 |
| 2 | Q | N | R | 42.09 | 0.434 |
| 3 | R | N | R | 0.92 | 0.434 |
| 4 | Q | K | H | 0.08 | 0.434 |
| 5 | Q | N | H | 0.08 | 0.434 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR4K17.aApr07-unspliced | main_exon | 5UTR | chr14 | 20,117,407 | 20,117,500 | + |
| CDS | chr14 | 20,117,500 | 20,118,435 | + | ||
| 3UTR | chr14 | 20,118,435 | 20,118,438 | + | ||