Search Olfactory receptors

(e.g. OR1G1, AF087928, Segregating Pseudo)

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OR52A5 Olfactory Receptor

Gene Symbol OR52A51 (View this gene in GeneCards)
Family 52
Subfamily A
Pseudogene No
CORP pseudogene probability score 0.18 (functional)
Aliases OR11-33, HsOR11.3.50
External Ids HGNC: 19580   GeneBank: AY726590, BK004433, NM_001005160   
Build #39 labels OR52A5
Chromosomal location 11:5,131,695-5,132,642 (-)
Cluster 11@5
Synteny CLIC#23
Remarks

Most Similar ORs in Humans (Paralogs)

Symbol Percent Length
OR52A1 74.84% 310
OR52A4 69.96% 263

Most Similar ORs in other species (Orthologs)

Specie Symbol Percent Length
Dog OR52A24 79% 316
Dog OR52A5C 81% 313
Dog OR52A5 80% 316
Chimp CONTIG*********** 98% 316
Mouse Or52a5 82% 314
Mouse Or52a5b 81% 314
Rat Or52a5 82% 314
Rat Or52a5b 81% 314
Cow OR52A5 85% 310
Cow OR52A5D 84% 310
Cow OR52A5EP 82% 318

Expression evidences

Source Accession
mRNA AB463976
GNF Atlas2 gnf1h10900_at

Sequence information

Nucleotide sequence ATGCCGACATTCAATGGCTCAGTCTTCATGCCCTCTGCGTTTATACTAATTGGGATTCCT
GGTCTGGAGTCAGTGCAGTGTTGGATTGGGATTCCTTTCTCTGCCATGTATCTTATTGGT
GTGATTGGAAATTCCCTAATTTTAGTTATAATCAAATATGAAAACAGCCTCCATATACCC
ATGTACATTTTTTTGGCCATGTTGGCAGCCACAGACATTGCACTTAACACCTGCATTCTT
CCCAAAATGTTAGGCATCTTCTGGTTTCATTTGCCAGAGATTTCTTTTGATGCCTGTCTT
TTTCAAATGTGGCTTATTCACTCATTCCAGGCAATTGAATCGGGTATCCTTCTGGCAATG
GCCCTGGATCGCTATGTGGCCATCTGTATCCCCTTGAGACATGCCACCATCTTTTCCCAG
CAGTTCTTAACTCATATTGGACTTGGGGTGACACTCAGGGCTGCCATTCTTATAATACCT
TCCTTAGGGCTCATCAAATGCTGTCTGAAACACTATCGAACTACAGTCATCTCTCACTCT
TACTGTGAGCACATGGCCATCGTGAAGCTGGCTACTGAAGATATCCGAGTCAACAAGATA
TATGGCCTATTTGTTGCCTTTGCAATCCTAGGGTTTGACATAATATTTATAACCTTGTCC
TATGTCCAAATTTTTATCACTGTCTTTCAGCTGCCCCAGAAGGAGGCACGATTCAAGGCC
TTTAATACATGCATTGCCCACATTTGTGTCTTCCTACAGTTCTACCTTCTTGCCTTCTTC
TCTTTCTTCACACACAGGTTTGGTTCACACATACCACCATATATTCATATCCTCTTGTCA
AATCTTTACCTGTTAGTCCCACCTTTTCTCAACCCTATTGTCTATGGAGTGAAGACCAAG
CAAATTCGTGACCATATTGTGAAAGTGTTTTTCTTCAAAAAAGTAACT
Conceptual translation MPTFNGSVFMPSAFILIGIPGLESVQCWIGIPFSAMYLIGVIGNSLILVIIKYENSLHIP
MYIFLAMLAATDIALNTCILPKMLGIFWFHLPEISFDACLFQMWLIHSFQAIESGILLAM
ALDRYVAICIPLRHATIFSQQFLTHIGLGVTLRAAILIIPSLGLIKCCLKHYRTTVISHS
YCEHMAIVKLATEDIRVNKIYGLFVAFAILGFDIIFITLSYVQIFITVFQLPQKEARFKA
FNTCIAHICVFLQFYLLAFFSFFTHRFGSHIPPYIHILLSNLYLLVPPFLNPIVYGVKTK
QIRDHIVKVFFFKKVT

Protein domains and features

Variations - SNPs

Chr Start End Type Variation AA Change SNP IDs
11 5,152,966 5,152,966 NS A/G C/R rs74051330 (DbSNP)
11 5,153,400 5,153,400 NS A/G I/T rs73396832 (DbSNP)
11 5,152,957 5,152,957 NS C/T V/I rs74051326 (DbSNP)
11 5,153,261 5,153,261 SYN G/A F/F rs2472530 (DbSNP)
11 5,132,031 5,132,031 SYN A/G F/F 1000GP (CEU, CHBJPT)
11 5,131,823 5,131,823 NS A/G Y/H 1000GP (CEU)
11 100 -100 NS T/C I/V 1000GP (YRI, YRI, YRI, YRI, YRI)

Variations - CNVs

Chr Start End Type Sources
11 5,150,925 5,153,972 CopyNumber #58 (Waszak)

Haplotypes

Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.

I306V R303C Y274H K239E I187V I158T V25L P2L % Freq CORP
1 I R Y K I I V P 94.39 0.401
2 V R Y K I I V P 3.00 0.401
3 I R Y K I I V L 0.77 0.401
4 V C Y K I I V P 0.61 0.401
5 I R Y E I I V P 0.38 0.401
6 I R H K I I V P 0.31 0.401
7 V R Y K V I V P 0.23 0.401
8 I R Y K I T V P 0.23 0.401
9 I R Y K I I L P 0.08 0.401

AceView Gene Models

The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.

Accession Type Chr Start End Strand
OR52A5.aApr07-unspliced main_exon 3UTR chr11 5,131,692 5,131,695 -
CDS chr11 5,131,695 5,132,642 -