OR52A4 Olfactory Receptor
| Gene Symbol | OR52A41 (View this gene in GeneCards) |
| Family | 52 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 1 (pseudogene) |
| Aliases | HsOR11.3.49P |
| External Ids | HGNC: 19579 GeneBank: NM_001005222 |
| Build #39 labels | OR52A4 |
| Chromosomal location | 11:5,120,667-5,121,578 (-) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR52A1 | 69.58% | 263 |
| OR52A5 | 69.96% | 263 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR52A6 | 83% | 263 |
| Mouse | Or52a24 | 71% | 263 |
| Rat | Or52a20 | 70% | 263 |
| Cow | OR52A1DP | 71% | 263 |
| Orang | OR52A4P | 89% | 265 |
| Horse | OR52A31 | 85% | 263 |
| Horse | OR52A32 | 85% | 261 |
| Chimp | OR52A4P | 90% | 281 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | DQ656009 |
Sequence information
| Nucleotide sequence |
ATGGCCCTGCCTATTACAAATGGTACCTTGTTCATGCCTTTTGTGCTGACATTTATTGGG ATCCCCGGTTTTGAATCTGTACAATGCTGGATTGGGATTCCATTCTGTGCTACGTATGTC ATTGCTCTGATTGGAAATTCTCTACTTTTGATCATCATCAAATCTGAGCCAAGCCTCCAT GAACCCATGTATATCTTCCTGGCCACGTTAGGAGCCACAGACATTTCACTTAGCACCAGC ATTGTGCCCAAGATGCTTGATATTTTTTGGTTCCATTTGCCAGAGATATATTTTGATGCT TGCCTCTTTCAGATGTGGCTCATCCACACATTTCAAGGCATTGAATCAGGAGTCCTGCTA GCCATGGCTCTGGACCGCTGTGTAGCGATCTGTTATCCTCTGAGGCGTGCTATAGTATTC ACTCGACAGCTAGTCACTTATATTGTAGTTGGAGTGACATTGCGGCCTGCCATTCTGGTA ATTCCATGCCTATTGCTTATAAAATGCCATCTGAAACTCTACCGAACCAAGTTAATATAC CACACTTACTGTGAACGCGTGGCCCTTGTGAAGCTTGCCACTGAAGATGTTTACATTAAT AAGGTCTATGGTATCCTTGGAGCATTTATTGTTGGTGGGCTTGACTTCATTTTCATCACC CTCTCCTATATTCAGATATTTATCACTGTCTTTCACTTGCCTCTGAAAGAGGCACGACTT AAGGTATTTAATACATGTATTCCCCATATATATGTCTTCTTCCAATTCTATCTCCTTGCT TTTTTTTTCATTTTTTACTCGCAGATTTGGATCTTATATCCCATCATATGTACATATCAC CTTGTCCAGTCTTTACCTACTGGTCCCACCATTCCTCAACCCCTTTATCTATGGGTTAAA GACCAAACACAT |
| Conceptual translation |
MALPITNGTLFMPFVLTFIGIPGFESVQCWIGIPFCATYVIALIGNSLLLIIIKSEPSLH EPMYIFLATLGATDISLSTSIVPKMLDIFWFHLPEIYFDACLFQMWLIHTFQGIESGVLL AMALDRCVAICYPLRRAIVFTRQLVTYIVVGVTLRPAILVIPCLLLIKCHLKLYRTKLIY HTYCERVALVKLATEDVYINKVYGILGAFIVGGLDFIFITLSYIQIFITVFHLPLKEARL KVFNTCIPHIYVFFQFYLLAFFFIFYSQIWILYPIICTYHLVQSLPTGPTIPQPLYLWVK DQTH Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 5,141,980 | 5,141,980 | NS | A/G | C/R | rs4426129 (DbSNP) |
| 11 | 5,142,403 | 5,142,403 | NS | A/G | C/R | rs61880361 (DbSNP) |
| 11 | 5,141,902 | 5,141,902 | NS | C/T | A/T | rs10837374 (DbSNP) |
| 11 | 5,142,549 | 5,142,549 | NS | C/T | G/D | rs7947334 (DbSNP) |
| 11 | 5,142,270 | 5,142,270 | NS | G/T | S/Y | rs10837375 (DbSNP) |
| 11 | 5,142,671 | 5,142,671 | SYN | A/G | N/N | rs7944388 (DbSNP) |
| 11 | 5,142,134 | 5,142,134 | SYN | C/T | Q/Q | rs11035760 (DbSNP) |
| 11 | 5,120,672 | 5,120,672 | NS | T/C | T/A | 1000GP (CEU, CHBJPT) |
| 11 | 5,121,319 | 5,121,319 | NS | T/C | D/G | 1000GP (CEU, CHBJPT) |
| 11 | 5,121,441 | 5,121,441 | SYN | A/G | N/N | 1000GP (CEU, CHBJPT) |
| 11 | 5,120,904 | 5,120,904 | SYN | C/T | Q/Q | 1000GP (CEU, CHBJPT) |
| 11 | 5,120,750 | 5,120,750 | NS | A/G | C/R | 1000GP (CEU, CHBJPT) |
| 11 | 5,121,040 | 5,121,040 | NS | T/G | Y/S | 1000GP (CEU, CHBJPT) |
| 11 | 5,121,300 | 5,121,300 | SYN | C/T | L/L | 1000GP (CHBJPT) |
| 11 | 100 | -100 | NS | T/C | T/A | 1000GP (YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | C/T | Q/Q | 1000GP (YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 5,139,897 | 5,142,908 | Deletion | #198 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| T303A | C277R | T220N | Y180S | D87G | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | A | R | T | S | G | 42.09 | 1.000 |
| 2 | A | R | T | S | D | 30.03 | 1.000 |
| 3 | T | C | T | Y | D | 25.50 | 1.000 |
| 4 | A | C | T | Y | D | 1.54 | 1.000 |
| 5 | A | R | N | S | G | 0.54 | 1.000 |
| 6 | T | R | T | Y | D | 0.15 | 1.000 |
| 7 | T | C | T | S | D | 0.08 | 1.000 |
| 8 | A | C | T | S | G | 0.08 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR52A4.aApr07 | main_exon | 3UTR | chr11 | 5,120,664 | 5,120,667 | - |
| CDS | chr11 | 5,120,667 | 5,121,578 | - | ||
| 5UTR | chr11 | 5,121,578 | 5,121,907 | - | ||
| exon_5UTR | chr11 | 5,122,633 | 5,122,778 | - | ||
| exon_5UTR | chr11 | 5,123,443 | 5,123,511 | - | ||
| exon_5UTR | chr11 | 5,124,468 | 5,124,513 | - | ||
| OR52A4.bApr07 | main_exon | CDS_partial | chr11 | 5,121,155 | 5,121,578 | - |
| 5UTR | chr11 | 5,121,578 | 5,121,907 | - | ||
| exon_5UTR | chr11 | 5,124,468 | 5,124,513 | - | ||