OR5AS1 Olfactory Receptor
| Gene Symbol | OR5AS11 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | AS |
| Pseudogene | No |
| CORP pseudogene probability score | 0.1 (functional) |
| Aliases | OR11-168, HsOR11.11.41, ORL3307 |
| External Ids | HGNC: 15261 GeneBank: AB065452, AB065543, BK004344, NM_001001921 ORDB: ORL3307 |
| Build #39 labels | OR5AS1 |
| Chromosomal location | 11:56,030,419-56,031,390 (+) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5AP2 | 55.48% | 301 |
| OR5AR1 | 55.74% | 305 |
| OR5I1 | 56.44% | 303 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5AR1 | 57% | 307 |
| Mouse | Or5as1 | 82% | 309 |
| Rat | Or5as1 | 81% | 309 |
| Cow | OR5AS1BP | 82% | 281 |
| Orang | OR5AU1 | 53% | 307 |
| Horse | OR5AS3P | 78% | 299 |
| Chimp | OR5AP2 | 56% | 303 |
Expression evidences
| Source | Accession |
|---|---|
| GNF Atlas2 | gnf1h05457_at |
Sequence information
| Nucleotide sequence |
ATGTTGGAGAGTAATTACACCATGCCAACTGAGTTCCTATTTGTTGGATTCACAGATTAT CTACCTCTCAGAGTCACACTGTTCTTGGTATTCCTTCTGGTATATACATTAACTATGGTC GGAAATATACTCTTAATAATTCTAGTTAATATTAATTCAAGCCTTCAAATTCCCATGTAT TATTTTCTTAGCAACTTATCTTTCTTAGACATCAGCTGTTCTACAGCAATCACTCCTAAA ATGCTGGCAAACTTCTTGGCATCCAGGAAAAGCATCTCTCCTTATGGGTGTGCACTACAA ATGTTTTTCTTCGCTTCTTTTGCTGATGCTGAGTGCCTTATCCTGGCAGCAATGGCTTAT GACCGCTATGCAGCCATCTGCAACCCACTGCTCTATACTACACTGATGTCTAGGAGAGTC TGTGTCTGCTTCATTGTGTTGGCATATTTCAGTGGAAGTACAACATCACTGGTCCATGTG TGCCTCACATTCAGGCTGTCATTTTGTGGCTCCAATATCGTCAATCATTTTTTCTGTGAT ATCCCACCTCTTCTGGCTTTATCATGTACAGACACTCAGATCAACCAGCTTCTGCTCTTT GCTTTGTGCAGCTTCATCCAGACCAGCACTTTTGTGGTAATATTTATTTCTTACTTCTGC ATCCTCATCACTGTGTTGAGCATCAAGTCCTCAGGTGGCAGAAGCAAAACATTCTCCACT TGTGCTTCCCACCTCATAGCAGTCACCTTATTCTATGGAGCGCTCCTGTTTATGTACTTA CAGCCCACCACTAGCTATTCCCTAGACACTGATAAGGTGGTGGCAGTGTTTTATACTGTT GTATTTCCCATGTTTAATCCAATAATTTATAGTTTCAGAAACAAGGATGTGAAAAATGCT CTCAAAAAGCTATTAGAAAGAATTGGATATTCAAATGAATGGTATTTAAATCGTTTAAGA ATAGTCAATATC |
| Conceptual translation |
MLESNYTMPTEFLFVGFTDYLPLRVTLFLVFLLVYTLTMVGNILLIILVNINSSLQIPMY YFLSNLSFLDISCSTAITPKMLANFLASRKSISPYGCALQMFFFASFADAECLILAAMAY DRYAAICNPLLYTTLMSRRVCVCFIVLAYFSGSTTSLVHVCLTFRLSFCGSNIVNHFFCD IPPLLALSCTDTQINQLLLFALCSFIQTSTFVVIFISYFCILITVLSIKSSGGRSKTFST CASHLIAVTLFYGALLFMYLQPTTSYSLDTDKVVAVFYTVVFPMFNPIIYSFRNKDVKNA LKKLLERIGYSNEWYLNRLRIVNI Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 55,798,779 | 55,798,778 | Ins(1) | -/G | rs35555163 (DbSNP) | |
| 11 | 55,798,823 | 55,798,823 | NS | A/G | Y/C | rs17600939 (DbSNP) |
| 11 | 55,798,259 | 55,798,259 | NS | G/T | R/L | rs12224086 (DbSNP) |
| 11 | 55,798,112 | 55,798,112 | NS | G/T | C/F | rs61307184 (DbSNP) |
| 11 | 55,798,533 | 55,798,533 | SYN | A/C | V/V | rs17528803 (DbSNP) |
| 11 | 55,798,152 | 55,798,152 | SYN | A/G | L/L | rs1482011 (DbSNP) |
| 11 | 55,798,761 | 55,798,761 | SYN | C/T | I/I | rs61889974 (DbSNP) |
| 11 | 55,798,237 | 55,798,237 | SYN | C/T | L/L | rs17528782 (DbSNP) |
| 11 | 55,798,764 | 55,798,764 | SYN | C/T | Y/Y | rs61889975 (DbSNP) |
| 11 | 56,031,347 | 56,031,347 | NS | A/G | Y/C | 1000GP (CEU) |
| 11 | 56,031,285 | 56,031,285 | SYN | T/C | I/I | 1000GP (CEU) |
| 11 | 56,030,676 | 56,030,676 | SYN | G/A | L/L | 1000GP (CEU, CHBJPT) |
| 11 | 56,030,761 | 56,030,761 | SYN | C/T | L/L | 1000GP (CEU) |
| 11 | 56,030,783 | 56,030,783 | NS | G/T | R/L | 1000GP (CEU, CHBJPT) |
| 11 | 56,031,057 | 56,031,057 | SYN | A/C | V/V | 1000GP (CEU) |
| 11 | 56,031,288 | 56,031,288 | SYN | T/C | Y/Y | 1000GP (CEU) |
| 11 | 100 | -100 | SYN | G/A | L/L | 1000GP (YRI, YRI, YRI) |
| 11 | 100 | -100 | NS | G/T | R/L | 1000GP (YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 55,153,930 | 55,816,828 | CopyNumber | Variation_0308 (DGV) |
| 11 | 55,689,863 | 55,849,156 | CopyNumber | Variation_2927 (DGV) |
| 11 | 54,835,623 | 55,879,426 | CopyNumber | Variation_8690 (DGV) |
| 11 | 55,685,799 | 55,842,512 | CopyNumber | Variation_9189 (DGV) |
| 11 | 55,685,556 | 55,819,544 | CopyNumber | Variation_29912 (DGV), Variation_48846 (DGV) |
| 11 | 55,685,556 | 55,836,620 | CopyNumber | Variation_48847 (DGV) |
| 11 | 55,683,109 | 55,833,490 | CopyNumber | Variation_85786 (DGV) |
| 11 | 55,797,795 | 55,800,866 | Deletion | #219 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| I47M | C73F | R122L | E306G | Y310C | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | I | C | R | E | Y | 83.72 | 0.195 |
| 2 | I | C | L | E | Y | 10.14 | 0.812 |
| 3 | I | C | R | E | C | 4.84 | 0.195 |
| 4 | I | C | R | G | Y | 0.77 | 0.195 |
| 5 | M | C | R | E | Y | 0.31 | 0.195 |
| 6 | I | F | R | E | Y | 0.23 | 0.195 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5AS1.aApr07-unspliced | main_exon | CDS | chr11 | 56,030,419 | 56,031,390 | + |
| 3UTR | chr11 | 56,031,390 | 56,031,393 | + | ||