OR5K3 Olfactory Receptor
| Gene Symbol | OR5K31 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | K |
| Pseudogene | No |
| CORP pseudogene probability score | 0.01 (functional) |
| Aliases | HsOR3.3.15 |
| External Ids | HGNC: 31290 GeneBank: NM_001005516 |
| Build #39 labels | OR5K3 |
| Chromosomal location | 3:98,390,666-98,391,628 (+) |
| Cluster | 3@98 |
| Synteny | CLIC#9 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5K1 | 74.35% | 308 |
| OR5K2 | 72.17% | 309 |
| OR5K4 | 75.24% | 319 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5K1 | 77% | 322 |
| Mouse | Or5k3 | 81% | 308 |
| Rat | Or5k3 | 81% | 308 |
| Cow | OR5K8 | 80% | 307 |
| Orang | OR5K3P | 91% | 321 |
| Horse | OR5K24 | 80% | 306 |
| Chimp | OR5K4 | 78% | 307 |
Sequence information
| Nucleotide sequence |
ATGAATAAGGAGAATCACTCCTTGATAGCTGAGTTCATCCTCACAGGATTTACATATCAT CCAAAGCTGAAGACTGTTCTGTTTGTGGTGTTCTTTGCCATCTATCTGATCACCATGGTG GGGAACATTGGTTTGGTGGCATTGATTTATATAGAGCAACGTCTTCACACACCAATGTAC ATATTTTTAGGCAACCTAGTTCTGATGGATTCCTGCTGTTCCTCTGCTATTACTCCCAAG ATGTTAGAGAACTTCTTTTCTGAGGACAAAAGGATTACCCTGTATGAATGTATGGCACAA TTTTATTTTCTCTGTCTTGCTGAAACTACAGACTGCTTTCTTCTGGCGGCAATGGCCTAT GACTGCTATGTGGCCATATGCAACCCACTGCAGTACCACACCATGATGTCCAAGACACTC TGCATTCAGATGACTGCAGGAGCCTACCTAGCTGGCAACCTGCATCCCATGATTGAAGTA GAGTTTCTGTTGAGGTTAACTTTCTGTGGGTCTCATCAAATCAATCATTTTTTCTGTGAT GTTCTTCCATTATATAGACTTTCTTGTATTAACCCTTATATCAATGAATTGGTGTTATTT ATCTTGGCAGGATCAATTCAAATCTTTACTATAGTCTTAGTTTCTTATTTCTACATCCTT TTCACAATATTTACAATGAAATCCAAGGAGGGAAGAGGCAAAGCTTTATCTACTTGTGCA TCTCACTTTCTCTCTGTGTCAATATTCTGTGATTCCCTTCTCTTCATGTATGCTCGACCA GGTGCAGTTAATGAAGGGGATAAAGATATACCTGTTGCTATATTTTATACTTTAGTTATT CCTTTATTAAATCCTTTTATTTATAGCCTAAGAAATAAGGAAGTAATAAATATTATGAAA AAAATTATGAAGAAGAGAAAATTTTGTCACATTCTGAAACAAATGTCATCCCCTCTGGCA ACT |
| Conceptual translation |
MNKENHSLIAEFILTGFTYHPKLKTVLFVVFFAIYLITMVGNIGLVALIYIEQRLHTPMY IFLGNLVLMDSCCSSAITPKMLENFFSEDKRITLYECMAQFYFLCLAETTDCFLLAAMAY DCYVAICNPLQYHTMMSKTLCIQMTAGAYLAGNLHPMIEVEFLLRLTFCGSHQINHFFCD VLPLYRLSCINPYINELVLFILAGSIQIFTIVLVSYFYILFTIFTMKSKEGRGKALSTCA SHFLSVSIFCDSLLFMYARPGAVNEGDKDIPVAIFYTLVIPLLNPFIYSLRNKEVINIMK KIMKKRKFCHILKQMSSPLAT Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 3 | 98,110,075 | 98,110,075 | NS | A/G | Y/C | rs62268325 (DbSNP) |
| 3 | 98,109,640 | 98,109,640 | NS | A/G | D/G | rs13068323 (DbSNP) |
| 3 | 98,110,306 | 98,110,306 | NS | C/G | A/G | rs73854831 (DbSNP) |
| 3 | 98,110,038 | 98,110,038 | NS | C/T | L/F | rs73854830 (DbSNP) |
| 3 | 98,109,709 | 98,109,709 | NS | C/T | A/V | rs58422508 (DbSNP) |
| 3 | 98,109,873 | 98,109,873 | NS | C/T | R/C | rs57067643 (DbSNP) |
| 3 | 98,390,796 | 98,390,796 | NS | G/A | G/D | 1000GP (CEU, CHBJPT) |
| 3 | 100 | -100 | NS | C/T | S/F | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 3 | 100 | -100 | SYN | C/T | S/S | 1000GP (YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| S7F | L36P | G44D | V67A | C122R | F177L | P260S | G266A | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | S | L | G | V | C | F | P | G | 74.73 | 0.026 |
| 2 | S | L | D | V | C | F | P | G | 17.28 | 0.026 |
| 3 | S | L | G | A | R | L | P | G | 4.76 | 0.019 |
| 4 | S | L | G | A | R | L | P | A | 1.54 | 0.019 |
| 5 | F | P | G | V | C | F | S | G | 1.31 | 0.026 |
| 6 | S | P | G | V | R | L | P | G | 0.08 | 0.002 |
| 7 | S | L | G | V | R | L | P | G | 0.08 | 0.002 |
| 8 | S | L | D | A | C | L | P | G | 0.08 | 0.260 |
| 9 | F | P | G | V | C | L | S | G | 0.08 | 0.026 |
| 10 | F | P | G | V | C | F | P | G | 0.08 | 0.026 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5K3.aApr07-unspliced | main_exon | CDS | chr3 | 98,390,666 | 98,391,628 | + |
| 3UTR | chr3 | 98,391,628 | 98,391,631 | + | ||