OR8B3 Olfactory Receptor
Gene Symbol | OR8B31 (View this gene in GeneCards) |
Family | 8 |
Subfamily | B |
Pseudogene | No |
CORP pseudogene probability score | |
Aliases | AC002556-B, OR11-311, HsOR11.18.34, ORL345 |
External Ids | HGNC: 8472 GeneBank: AB065827, AB065830, BK004204, NM_001005467 ORDB: ORL345 |
Build #39 labels | OR8B3 |
Chromosomal location | 11:124,396,413-124,397,351 (-) |
Cluster | 11@124 |
Synteny | CLIC#29 |
Remarks |
Most Similar ORs in Humans (Paralogs)
Symbol | Percent | Length |
---|---|---|
OR8B2 | 97.76% | 313 |
Most Similar ORs in other species (Orthologs)
Specie | Symbol | Percent | Length |
---|---|---|---|
Dog | OR8B3FP | 85% | 294 |
Mouse | Or8b3 | 83% | 313 |
Mouse | Or8b3b | 81% | 310 |
Rat | Or8b3 | 84% | 313 |
Rat | Or8b3c | 84% | 313 |
Cow | OR8B3G | 86% | 310 |
Orang | OR8B2 | 95% | 313 |
Horse | OR8B3H | 89% | 314 |
Chimp | OR8B2 | 96% | 313 |
Expression evidences
Source | Accession |
---|---|
ESTs | DN914774 |
Sequence information
Nucleotide sequence |
ATGCTGGCTAGAAACAACTCCTTAGTGACTGAATTTATTCTTGCTGGATTAACAGATCAT CCAGAGTTCCAGCAACCCCTCTTTTTCCTGTTTCTAGTGGTCTACATTGTCACCATGGTA GGCAACCTTGGCTTGATCATTCTTTTCGGTCTAAATTCTCACCTCCACACACCAATGTAC TATTTCCTCTTCAATCTCTCCTTCATTGATCTCTGTTACTCCTCTGTTTTCACTCCCAAA ATGCTAATGAACTTTGTATCAAAAAAGAATATTATCTCCTATGTTGGGTGCATGACTCAG CTGTTTTTCTTTCTCTTTTTTGTCATCTCTGAATGTTACATGTTGACCTCAATGGCATAT GATCGCTATGTGGCCATCTGTAATCCATTGCTGTATAAGGTCACCATGTCCCATCAGGTC TGTTCTATGCTCACTTTTGCTGCTTACATAATGGGATTGGCTGGAGCCACGGCCCACACC GGGTGCATGCTTAGACTCACCTTCTGCAGTGCTAATATCATCAACCATTACTTGTGTGAC ATACTCCCCCTCCTCCAGCTTTCCTGCACCAGCACCTATGTCAACGAGGTGGTTGTTCTC ATTGTTGTGGGTATTAATATCATGGTACCCAGTTGTACCATCCTCATTTCTTATGTTTTC ATTGTCACTAGCATTCTTCATATCAAATCCACTCAAGGAAGATCAAAAGCCTTCAGTACT TGTAGCTCTCATGTCATTGCTCTGTCTCTGTTTTTTGGGTCAGCGGCATTCATGTATATT AAATATTCTTCTGGATCTATGGAGCAGGGAAAAGTTTCTTCTGTTTTCTACACTAATGTG GTGCCCATGCTCAATCCTCTCATCTACAGTTTGAGGAACAAGGATGTCAAAGTTGCACTG AGGAAAGCTCTGATTAAAATTCAGAGAAGAAATATATTC |
Conceptual translation |
MLARNNSLVTEFILAGLTDHPEFQQPLFFLFLVVYIVTMVGNLGLIILFGLNSHLHTPMY YFLFNLSFIDLCYSSVFTPKMLMNFVSKKNIISYVGCMTQLFFFLFFVISECYMLTSMAY DRYVAICNPLLYKVTMSHQVCSMLTFAAYIMGLAGATAHTGCMLRLTFCSANIINHYLCD ILPLLQLSCTSTYVNEVVVLIVVGINIMVPSCTILISYVFIVTSILHIKSTQGRSKAFST CSSHVIALSLFFGSAAFMYIKYSSGSMEQGKVSSVFYTNVVPMLNPLIYSLRNKDVKVAL RKALIKIQRRNIF Protein domains and features |
Variations - SNPs
Chr | Start | End | Type | Variation | AA Change | SNP IDs |
---|---|---|---|---|---|---|
11 | 100 | -100 | NS | C/T | M/I | 1000GP (YRI) |
11 | 100 | -100 | SYN | A/G | C/C | 1000GP (YRI) |
11 | 124,266,390 | 124,266,390 | SYN | A/G | P/P | rs28496031 (DbSNP) |
11 | 124,266,906 | 124,266,906 | NS | T/C | I/M | rs530992 (DbSNP) |
11 | 124,266,912 | 124,266,912 | SYN | A/G | C/C | rs28398895 (DbSNP) |
11 | 124,266,990 | 124,266,990 | SYN | C/T | V/V | rs4287348 (DbSNP) |
11 | 124,267,177 | 124,267,177 | NS | C/T | R/Q | rs61910862 (DbSNP) |
11 | 124,267,189 | 124,267,189 | NS | T/C | H/R | rs507335 (DbSNP) |
11 | 124,397,010 | 124,397,010 | NS | C/T | M/I | 1000GP (CEU, CHBJPT) |
11 | 124,397,016 | 124,397,016 | SYN | A/G | C/C | 1000GP (CEU, CHBJPT) |
Variations - CNVs
Chr | Start | End | Type | Sources |
---|---|---|---|---|
CopyNumber | 54 (Hasin) | |||
11 | 124,253,480 | 124,270,036 | CopyNumber | Variation_22874 (DGV) |
11 | 124,253,880 | 124,269,631 | CopyNumber | Variation_101365 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
C212F | V34I | Q24R | H20R | % Freq | CORP | |
---|---|---|---|---|---|---|
1 | C | V | R | R | 59.45 | 0.441 |
2 | C | I | R | R | 23.96 | 0.441 |
3 | C | V | Q | H | 14.21 | 0.441 |
4 | F | I | R | R | 1.77 | 0.441 |
5 | C | V | Q | R | 0.23 | 0.441 |
6 | C | I | Q | H | 0.23 | 0.441 |
7 | C | V | R | H | 0.15 | 0.441 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
Accession | Type | Chr | Start | End | Strand | |
---|---|---|---|---|---|---|
OR8B3andOR8B2.bApr07-unspliced | main_exon | 3UTR | chr11 | 124,396,410 | 124,396,413 | - |
CDS | chr11 | 124,396,413 | 124,397,351 | - |