OR8B3 Olfactory Receptor
| Gene Symbol | OR8B31 (View this gene in GeneCards) |
| Family | 8 |
| Subfamily | B |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | AC002556-B, OR11-311, HsOR11.18.34, ORL345 |
| External Ids | HGNC: 8472 GeneBank: AB065827, AB065830, BK004204, NM_001005467 ORDB: ORL345 |
| Build #39 labels | OR8B3 |
| Chromosomal location | 11:124,396,413-124,397,351 (-) |
| Cluster | 11@124 |
| Synteny | CLIC#29 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR8B2 | 97.76% | 313 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR8B3FP | 85% | 294 |
| Mouse | Or8b3 | 83% | 313 |
| Mouse | Or8b3b | 81% | 310 |
| Rat | Or8b3 | 84% | 313 |
| Rat | Or8b3c | 84% | 313 |
| Cow | OR8B3G | 86% | 310 |
| Orang | OR8B2 | 95% | 313 |
| Horse | OR8B3H | 89% | 314 |
| Chimp | OR8B2 | 96% | 313 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | DN914774 |
Sequence information
| Nucleotide sequence |
ATGCTGGCTAGAAACAACTCCTTAGTGACTGAATTTATTCTTGCTGGATTAACAGATCAT CCAGAGTTCCAGCAACCCCTCTTTTTCCTGTTTCTAGTGGTCTACATTGTCACCATGGTA GGCAACCTTGGCTTGATCATTCTTTTCGGTCTAAATTCTCACCTCCACACACCAATGTAC TATTTCCTCTTCAATCTCTCCTTCATTGATCTCTGTTACTCCTCTGTTTTCACTCCCAAA ATGCTAATGAACTTTGTATCAAAAAAGAATATTATCTCCTATGTTGGGTGCATGACTCAG CTGTTTTTCTTTCTCTTTTTTGTCATCTCTGAATGTTACATGTTGACCTCAATGGCATAT GATCGCTATGTGGCCATCTGTAATCCATTGCTGTATAAGGTCACCATGTCCCATCAGGTC TGTTCTATGCTCACTTTTGCTGCTTACATAATGGGATTGGCTGGAGCCACGGCCCACACC GGGTGCATGCTTAGACTCACCTTCTGCAGTGCTAATATCATCAACCATTACTTGTGTGAC ATACTCCCCCTCCTCCAGCTTTCCTGCACCAGCACCTATGTCAACGAGGTGGTTGTTCTC ATTGTTGTGGGTATTAATATCATGGTACCCAGTTGTACCATCCTCATTTCTTATGTTTTC ATTGTCACTAGCATTCTTCATATCAAATCCACTCAAGGAAGATCAAAAGCCTTCAGTACT TGTAGCTCTCATGTCATTGCTCTGTCTCTGTTTTTTGGGTCAGCGGCATTCATGTATATT AAATATTCTTCTGGATCTATGGAGCAGGGAAAAGTTTCTTCTGTTTTCTACACTAATGTG GTGCCCATGCTCAATCCTCTCATCTACAGTTTGAGGAACAAGGATGTCAAAGTTGCACTG AGGAAAGCTCTGATTAAAATTCAGAGAAGAAATATATTC |
| Conceptual translation |
MLARNNSLVTEFILAGLTDHPEFQQPLFFLFLVVYIVTMVGNLGLIILFGLNSHLHTPMY YFLFNLSFIDLCYSSVFTPKMLMNFVSKKNIISYVGCMTQLFFFLFFVISECYMLTSMAY DRYVAICNPLLYKVTMSHQVCSMLTFAAYIMGLAGATAHTGCMLRLTFCSANIINHYLCD ILPLLQLSCTSTYVNEVVVLIVVGINIMVPSCTILISYVFIVTSILHIKSTQGRSKAFST CSSHVIALSLFFGSAAFMYIKYSSGSMEQGKVSSVFYTNVVPMLNPLIYSLRNKDVKVAL RKALIKIQRRNIF Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | C/T | M/I | 1000GP (YRI) |
| 11 | 100 | -100 | SYN | A/G | C/C | 1000GP (YRI) |
| 11 | 124,266,390 | 124,266,390 | SYN | A/G | P/P | rs28496031 (DbSNP) |
| 11 | 124,266,906 | 124,266,906 | NS | T/C | I/M | rs530992 (DbSNP) |
| 11 | 124,266,912 | 124,266,912 | SYN | A/G | C/C | rs28398895 (DbSNP) |
| 11 | 124,266,990 | 124,266,990 | SYN | C/T | V/V | rs4287348 (DbSNP) |
| 11 | 124,267,177 | 124,267,177 | NS | C/T | R/Q | rs61910862 (DbSNP) |
| 11 | 124,267,189 | 124,267,189 | NS | T/C | H/R | rs507335 (DbSNP) |
| 11 | 124,397,010 | 124,397,010 | NS | C/T | M/I | 1000GP (CEU, CHBJPT) |
| 11 | 124,397,016 | 124,397,016 | SYN | A/G | C/C | 1000GP (CEU, CHBJPT) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 54 (Hasin) | |||
| 11 | 124,253,480 | 124,270,036 | CopyNumber | Variation_22874 (DGV) |
| 11 | 124,253,880 | 124,269,631 | CopyNumber | Variation_101365 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| C212F | V34I | Q24R | H20R | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | C | V | R | R | 59.45 | 0.441 |
| 2 | C | I | R | R | 23.96 | 0.441 |
| 3 | C | V | Q | H | 14.21 | 0.441 |
| 4 | F | I | R | R | 1.77 | 0.441 |
| 5 | C | V | Q | R | 0.23 | 0.441 |
| 6 | C | I | Q | H | 0.23 | 0.441 |
| 7 | C | V | R | H | 0.15 | 0.441 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR8B3andOR8B2.bApr07-unspliced | main_exon | 3UTR | chr11 | 124,396,410 | 124,396,413 | - |
| CDS | chr11 | 124,396,413 | 124,397,351 | - | ||