OR11H4 Olfactory Receptor
| Gene Symbol | OR11H41 (View this gene in GeneCards) |
| Family | 11 |
| Subfamily | H |
| Pseudogene | No |
| CORP pseudogene probability score | 0.1 (functional) |
| Aliases | OR14-36, HsOR14.1.29, ORL3686 |
| External Ids | HGNC: 15347 GeneBank: AB065887, BK004455, NM_001004479 ORDB: ORL3686 |
| Build #39 labels | OR11H4 |
| Chromosomal location | 14:20,242,822-20,243,763 (+) |
| Cluster | 14@20b |
| Synteny | CLIC#32 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR11H5P | 68.01% | 297 |
| OR11H6 | 68.4% | 307 |
| OR11H7P | 68.15% | 314 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR11H7 | 70% | 314 |
| Mouse | Or11h4 | 89% | 313 |
| Mouse | Or11h4b | 87% | 313 |
| Rat | Or11h4 | 87% | 313 |
| Rat | Or11h4d | 84% | 313 |
| Cow | OR11H7 | 70% | 314 |
| Orang | OR11H5P | 69% | 303 |
| Horse | OR11H7 | 71% | 314 |
| Chimp | OR11H7 | 69% | 314 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB529289 |
Sequence information
| Nucleotide sequence |
ATGAACAGGTCAGCAACACACATCGTGACAGAGTTTATTCTCCTGGGATTCCCTGGTTGC TGGAAGATTCAGATTTTCCTCTTCTCATTGTTTTTGGTGATTTATGTCTTGACCTTGCTG GGAAATGGAGCCATCATCTATGCAGTGAGATGCAACCCACTACTACACACCCCCATGTAC TTTCTGCTGGGAAATTTTGCCTTCCTTGAGATCTGGTATGTGTCCTCCACTATTCCTAAC ATGCTAGTCAACATTCTCTCCAAGACCAAGGCCATCTCATTTTCTGGGTGCTTCCTCCAG TTCTATTTCTTCTTTTCACTGGGAACAACTGAATGTCTCTTTCTGGCAGTAATGGCTTAT GATCGATACCTGGCCATCTGCCACCCACTGCAGTACCCTGCCATCATGACTGTAAGGTTC TGTGGTAAGCTGGTGTCTTTCTGTTGGCTTATTGGATTCCTTGGATACCCAATTCCCATT TTCTACATCTCCCAACTCCCCTTCTGTGGTCCTAATATCATTGATCACTTCCTGTGTGAC ATGGACCCATTGATGGCTCTATCCTGTGCCCCAGCTCCCATAACTGAATGTATTTTCTAT ACTCAGAGCTCCCTTGTCCTCTTTTTCACTAGTATGTACATTCTTCGATCCTATATCCTG TTACTAACAGCTGTTTTTCAGGTCCCTTCTGCAGCTGGTCGGAGAAAAGCCTTCTCTACC TGTGGTTCTCATTTGGTTGTGGTATCTCTTTTCTATGGGACAGTCATGGTAATGTATGTA AGTCCTACATATGGGATCCCAACTTTATTGCAGAAGATCCTCACACTGGTATATTCAGTA ACGACTCCTCTTTTTAATCCTCTGATCTATACTCTTCGTAATAAGGACATGAAACTCGCT CTGAGAAATGTCCTGTTTGGAATGAGAATTCGTCAAAATTCG |
| Conceptual translation |
MNRSATHIVTEFILLGFPGCWKIQIFLFSLFLVIYVLTLLGNGAIIYAVRCNPLLHTPMY FLLGNFAFLEIWYVSSTIPNMLVNILSKTKAISFSGCFLQFYFFFSLGTTECLFLAVMAY DRYLAICHPLQYPAIMTVRFCGKLVSFCWLIGFLGYPIPIFYISQLPFCGPNIIDHFLCD MDPLMALSCAPAPITECIFYTQSSLVLFFTSMYILRSYILLLTAVFQVPSAAGRRKAFST CGSHLVVVSLFYGTVMVMYVSPTYGIPTLLQKILTLVYSVTTPLFNPLIYTLRNKDMKLA LRNVLFGMRIRQNS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 14 | 20,711,344 | 20,711,344 | NS | C/G | R/G | rs45438498 (DbSNP) |
| 14 | 20,711,852 | 20,711,852 | NS | C/G | T/S | rs17277270 (DbSNP) |
| 14 | 20,711,811 | 20,711,811 | SYN | A/G | V/V | rs17277263 (DbSNP) |
| 14 | 20,243,522 | 20,243,522 | NS | G/A | R/Q | 1000GP (CEU) |
| 14 | 20,243,693 | 20,243,693 | NS | C/G | T/S | 1000GP (CEU) |
| 14 | 20,243,310 | 20,243,310 | SYN | C/T | I/I | 1000GP (CHBJPT) |
| 14 | 100 | -100 | nonsense SNP | T/A | Y/* | 1000GP (YRI) |
| 14 | 100 | -100 | NS | G/A | R/Q | 1000GP (YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 14 | 20,203,125 | 20,716,841 | CopyNumber | Variation_8765 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| Y57* | V59A | F108L | D192H | R244Q | T301S | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | Y | V | F | D | R | T | 90.94 | 0.964 |
| 2 | Y | V | F | D | R | S | 7.91 | 0.964 |
| 3 | * | V | F | D | R | T | 0.46 | 1.200 |
| 4 | Y | A | F | D | R | T | 0.23 | 0.964 |
| 5 | Y | V | F | D | Q | T | 0.23 | 0.964 |
| 6 | Y | V | L | D | R | T | 0.15 | 0.964 |
| 7 | Y | V | F | H | R | T | 0.08 | 0.964 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR11H4.aApr07-unspliced | main_exon | 5UTR | chr14 | 20,242,792 | 20,242,822 | + |
| CDS | chr14 | 20,242,822 | 20,243,763 | + | ||
| 3UTR | chr14 | 20,243,763 | 20,243,766 | + | ||