OR1C1 Olfactory Receptor
| Gene Symbol | OR1C11 (View this gene in GeneCards) |
| Family | 1 |
| Subfamily | C |
| Pseudogene | No |
| CORP pseudogene probability score | 0.01 (functional) |
| Aliases | HSTPCR27, OR1-42, HsOR1.5.10, ORL3029, ORL211 |
| External Ids | HGNC: 8182 GeneBank: AB065625, AF399560, BK004365, HSTPCR27P, NM_012353 ORDB: ORL3029, ORL211 |
| Build #39 labels | OR1C1 |
| Chromosomal location | 1:247,757,465-247,758,406 (-) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR1F1 | 60% | 305 |
| OR1F12 | 55.41% | 305 |
| OR1J4 | 53.35% | 313 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR1AB2 | 59% | 313 |
| Mouse | Or1ab2 | 57% | 310 |
| Rat | Or1f33 | 59% | 309 |
| Cow | OR1F1BP | 60% | 305 |
| Orang | OR1F1 | 61% | 305 |
| Horse | OR1F1 | 59% | 307 |
| Chimp | OR1F1P | 61% | 303 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB529299 |
| GNF Atlas2 | gnf1h03759_at |
Sequence information
| Nucleotide sequence |
ATGGAAAAAAGAAATCTAACAGTTGTCAGGGAATTCGTCCTTCTGGGACTTCCTAGCTCA GCAGAGCAGCAGCACCTCCTGTCTGTGCTCTTTCTCTGTATGTATTTAGCCACCACCTTG GGGAACATGCTCATCATTGCGACGATTGGCTTTGACTCTCACCTCCATTCCCCTATGTAC TTCTTCCTTAGTAACTTGGCCTTTGTTGACATCTGCTTTACGTCGACTACAGTCCCCCAA ATGGTAGTGAATATCTTGACTGGCACCAAGACTATCTCTTTTGCAGGCTGCCTCACCCAG CTCTTCTTCTTCGTTTCTTTTGTGAATATGGACAGCCTCCTTCTGTGTGTGATGGCGTAT GATAGATATGTGGCGATTTGCCACCCCTTACATTACACCGCCAGAATGAACCTGTGCCTT TGTGTCCAGCTAGTGGCTGGACTGTGGCTTGTTACTTACCTCCACGCCCTCCTGCATACT GTCCTAATAGCACAGCTGTCCTTCTGTGCCTCCAATATCATCCATCATTTCTTCTGTGAT CTCAATCCTCTCCTGCAGCTCTCTTGCTCTGACGTCTCCTTCAATGTAATGATCATTTTT GCAGTAGGAGGTCTATTGGCTCTCACGCCCCTTGTCTGTATCCTCGTATCTTATGGACTT ATCTTCTCCACTGTTCTGAAGATCACCTCTACTCAGGGCAAGCAGAGAGCTGTTTCCACC TGCAGCTGCCACCTGTCAGTGGTGGTGTTGTTTTACGGCACAGCCATCGCCGTCTATTTC AGCCCTTCATCCCCCCATATGCCTGAGAGCGACACTCTGTCAACCATCATGTATTCAATG GTGGCTCCGATGCTGAATCCTTTCATCTATACCCTAAGGAACAGGGATATGAAGAGGGGA CTTCAGAAAATGCTTCTCAAGTGCACAGTCTTTCAGCAGCAA |
| Conceptual translation |
MEKRNLTVVREFVLLGLPSSAEQQHLLSVLFLCMYLATTLGNMLIIATIGFDSHLHSPMY FFLSNLAFVDICFTSTTVPQMVVNILTGTKTISFAGCLTQLFFFVSFVNMDSLLLCVMAY DRYVAICHPLHYTARMNLCLCVQLVAGLWLVTYLHALLHTVLIAQLSFCASNIIHHFFCD LNPLLQLSCSDVSFNVMIIFAVGGLLALTPLVCILVSYGLIFSTVLKITSTQGKQRAVST CSCHLSVVVLFYGTAIAVYFSPSSPHMPESDTLSTIMYSMVAPMLNPFIYTLRNRDMKRG LQKMLLKCTVFQQQ Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 247,921,083 | 247,921,083 | NS | A/G | M/T | rs12068080 (DbSNP) |
| 1 | 247,921,238 | 247,921,238 | SYN | A/G | L/L | rs41304161 (DbSNP) |
| 1 | 247,921,412 | 247,921,412 | SYN | C/G | T/T | rs41304163 (DbSNP) |
| 1 | 247,921,352 | 247,921,352 | SYN | C/T | A/A | rs1552813 (DbSNP) |
| 1 | 247,921,100 | 247,921,100 | SYN | G/T | G/G | rs1552812 (DbSNP) |
| 1 | 247,758,050 | 247,758,050 | SYN | C/T | A/A | 1000GP (CEU, CHBJPT) |
| 1 | 247,757,798 | 247,757,798 | SYN | T/G | G/G | 1000GP (CEU, CHBJPT) |
| 1 | 247,758,110 | 247,758,110 | SYN | G/C | T/T | 1000GP (CEU) |
| 1 | 247,757,956 | 247,757,956 | NS | C/A | V/F | 1000GP (CHBJPT) |
| 1 | 247,757,966 | 247,757,966 | SYN | T/C | G/G | 1000GP (CHBJPT) |
| 1 | 100 | -100 | NS | G/A | T/M | 1000GP (YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | T/G | G/G | 1000GP (YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 247,753,334 | 248,322,316 | CopyNumber | Variation_2358 (DGV) |
| 1 | 247,714,585 | 248,277,146 | CopyNumber | Variation_3339 (DGV) |
| 1 | 247,074,430 | 248,328,835 | CopyNumber | Variation_6816 (DGV) |
| 1 | 247,753,207 | 248,376,070 | CopyNumber | Variation_8353 (DGV) |
| 1 | 247,849,473 | 248,277,638 | CopyNumber | Variation_48302 (DGV) |
| 1 | 247,849,473 | 248,285,441 | CopyNumber | Variation_48303 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| T209M | C179R | A67V | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | T | C | A | 97.00 | 0.019 |
| 2 | T | C | V | 1.61 | 0.001 |
| 3 | M | C | A | 0.77 | 0.019 |
| 4 | T | R | A | 0.61 | 0.076 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR1C1.aApr07-unspliced | main_exon | 3UTR | chr1 | 247,757,462 | 247,757,465 | - |
| CDS | chr1 | 247,757,465 | 247,758,406 | - | ||