OR1D2 Olfactory Receptor
| Gene Symbol | OR1D21 (View this gene in GeneCards) |
| Family | 1 |
| Subfamily | D |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | OR17-4, OR17-6, HsOR17.1.2, ORL521, ORL19 |
| External Ids | HGNC: 8183 GeneBank: AF087917, AF399535, BC069552, BK004244, HSU04678, NM_002548 ORDB: ORL521, ORL19 |
| Build #39 labels | OR1D2 |
| Chromosomal location | 17:3,092,061-3,092,996 (-) |
| Cluster | 17@3b |
| Synteny | CLIC#39 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR1D3P | 84.98% | 313 |
| OR1D4 | 82.26% | 310 |
| OR1D5 | 82.58% | 310 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR1D10P | 81% | 335 |
| Dog | OR1D3BP | 80% | 313 |
| Mouse | Or1d2 | 87% | 312 |
| Rat | Or1d2 | 85% | 312 |
| Cow | OR1D3 | 86% | 310 |
| Orang | OR1D3C | 94% | 312 |
| Horse | OR1D3 | 87% | 313 |
| Chimp | OR1D4B | 85% | 310 |
| Chimp | OR1D3P | 83% | 313 |
| Chimp | OR1D4 | 84% | 310 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | CO247635 |
| mRNA | AB529300 |
| GNF Atlas2 | 221464_at |
Sequence information
| Nucleotide sequence |
ATGGATGGAGGCAACCAGAGTGAAGGTTCAGAGTTCCTTCTCCTGGGGATGTCAGAGAGT CCTGAGCAGCAGCGGATCCTGTTTTGGATGTTCCTGTCCATGTACCTGGTCACGGTGGTG GGAAATGTGCTCATCATCCTGGCCATCAGCTCTGATTCCCGCCTGCACACCCCCGTGTAC TTCTTCCTGGCCAACCTCTCCTTCACTGACCTCTTCTTTGTCACCAACACAATCCCCAAG ATGCTGGTGAACCTCCAGTCCCATAACAAAGCCATCTCCTATGCAGGGTGTCTGACACAG CTCTACTTCCTGGTCTCCTTGGTGGCCCTGGACAACCTCATCCTGGCTGTGATGGCATAT GACCGCTATGTGGCCATCTGCTGCCCCCTCCACTACACCACAGCCATGAGCCCTAAGCTC TGTATCTTACTCCTTTCCTTGTGTTGGGTCCTATCCGTCCTCTATGGCCTCATACACACC CTCCTCATGACCAGAGTGACCTTCTGTGGGTCACGAAAAATCCACTACATCTTCTGTGAG ATGTATGTATTGCTGAGGATGGCATGTTCCAACATTCAGATTAATCACACAGTGCTGATT GCCACAGGCTGCTTCATCTTCCTCATTCCCTTTGGATTCGTGATCATTTCCTATGTGCTG ATTATCAGAGCCATCCTCAGAATACCCTCAGTCTCTAAGAAATACAAAGCCTTCTCCACC TGTGCCTCCCATTTGGGTGCAGTCTCCCTCTTCTATGGGACACTTTGTATGGTATACCTA AAGCCCCTCCATACCTACTCTGTGAAGGACTCAGTAGCCACAGTGATGTATGCTGTGGTG ACACCCATGATGAATCCCTTCATCTACAGCCTGAGGAACAAGGACATGCATGGGGCTCTG GGAAGACTCCTAGATAAACACTTTAAGAGGCTGACA |
| Conceptual translation |
MDGGNQSEGSEFLLLGMSESPEQQRILFWMFLSMYLVTVVGNVLIILAISSDSRLHTPVY FFLANLSFTDLFFVTNTIPKMLVNLQSHNKAISYAGCLTQLYFLVSLVALDNLILAVMAY DRYVAICCPLHYTTAMSPKLCILLLSLCWVLSVLYGLIHTLLMTRVTFCGSRKIHYIFCE MYVLLRMACSNIQINHTVLIATGCFIFLIPFGFVIISYVLIIRAILRIPSVSKKYKAFST CASHLGAVSLFYGTLCMVYLKPLHTYSVKDSVATVMYAVVTPMMNPFIYSLRNKDMHGAL GRLLDKHFKRLT Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 17 | 100 | -100 | NS | G/A | T/I | 1000GP (YRI, YRI, YRI, YRI) |
| 17 | 2,995,572 | 2,995,572 | NS | A/G | I/T | rs4300683 (DbSNP) |
| 17 | 2,995,651 | 2,995,651 | NS | C/T | V/M | rs55803944 (DbSNP) |
| 17 | 2,995,658 | 2,995,658 | NS | A/T | F/L | rs61736110 (DbSNP) |
| 17 | 2,995,662 | 2,995,662 | NS | C/G | R/P | rs61736104 (DbSNP) |
| 17 | 2,995,698 | 2,995,698 | NS | G/A | A/V | rs61736106 (DbSNP) |
| 17 | 2,995,707 | 2,995,707 | NS | A/T | I/N | rs61736111 (DbSNP) |
| 17 | 2,995,716 | 2,995,716 | NS | G/A | T/I | rs61736112 (DbSNP) |
| 17 | 2,995,876 | 2,995,876 | NS | T/C | K/E | rs61736107 (DbSNP) |
| 17 | 2,995,927 | 2,995,927 | NS | A/G | C/R | rs73300984 (DbSNP) |
| 17 | 2,995,994 | 2,995,994 | SYN | T/C | T/T | rs769424 (DbSNP) |
| 17 | 2,996,199 | 2,996,199 | NS | A/T | F/Y | rs9916628 (DbSNP) |
| 17 | 2,996,217 | 2,996,217 | NS | T/C | Q/R | rs769423 (DbSNP) |
| 17 | 3,092,278 | 3,092,278 | NS | G/A | T/I | 1000GP (CEU) |
| 17 | 3,092,302 | 3,092,302 | NS | G/A | S/F | 1000GP (CEU) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 114 (Hasin) | |||
| 17 | 2,993,355 | 2,996,390 | CopyNumber | #96 (Waszak) |
| 17 | 2,995,650 | 2,995,872 | Del(-15) | #26(modil) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| I288V | T240I | S232F | V214M | P210R | H175Y | R122C | F31Y | R25Q | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | I | T | S | V | P | H | R | F | R | 73.12 | 0.478 |
| 2 | I | I | S | V | P | H | R | F | R | 13.67 | 0.772 |
| 3 | I | T | S | V | P | H | R | F | Q | 8.53 | 0.478 |
| 4 | I | T | S | V | P | H | R | Y | R | 1.54 | 0.512 |
| 5 | I | I | S | M | P | H | R | F | R | 1.38 | 0.772 |
| 6 | I | I | S | V | R | H | R | F | R | 1.15 | 0.600 |
| 7 | I | T | S | V | P | Y | R | F | R | 0.23 | 0.478 |
| 8 | V | I | S | V | P | H | R | F | R | 0.15 | 0.772 |
| 9 | I | I | F | M | P | H | R | F | R | 0.08 | 0.772 |
| 10 | I | T | F | V | P | H | R | F | R | 0.08 | 0.478 |
| 11 | V | I | S | V | P | H | C | F | R | 0.08 | 0.984 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR1D2.aApr07-unspliced | main_exon | 3UTR | chr17 | 3,092,058 | 3,092,061 | - |
| CDS | chr17 | 3,092,061 | 3,092,996 | - | ||
| 5UTR | chr17 | 3,092,996 | 3,093,004 | - | ||